6RXZ: Periodic tryptophan protein 2-like protein
Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum, state b. Determined by electron microscopy at 4.4 Å resolution. Released 14 Aug 2019.
- Method
- Electron microscopy
- Resolution
- 4.4 Å
- Organism
- Chaetomium thermophilum
- Chains
- 68
- Atoms
- 218,474
- Mol. weight
- 4828.8 kDa
- Ligands
- ZN
- Released
- 14 Aug 2019
Explore 6RXZ in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
6RXZ contains 943 α-helices and 998 β-strands across 66 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain CA: 7 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 67 | 1 | 233 |
| β-strand | 70-75 | 6 | 234 |
| β-strand | 82-85 | 4 | 234 |
| β-strand | 90 | 1 | 28 |
| β-strand | 91-95 | 5 | 234 |
| β-strand | 108-110 | 3 | 234 |
| β-strand | 126-129 | 4 | 234 |
| α-helix | 136-143 | 8 | |
| β-strand | 155-157 | 3 | 30 |
| α-helix | 165-174 | 10 | |
| β-strand | 179-184 | 6 | 30 |
| α-helix | 188-199 | 12 | |
| β-strand | 203-207 | 5 | 30 |
| α-helix | 213-218 | 6 | |
| β-strand | 225-228 | 4 | 30 |
| α-helix | 235-245 | 11 | |
| β-strand | 251-258 | 8 | 30 |
| α-helix | 259-262 | 4 | |
| α-helix | 268-281 | 14 | |
| β-strand | 284-290 | 7 | 30 |
| β-strand | 299-306 | 8 | 30 |
Chain Cb: 6 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 10 | 1 | 166 |
| β-strand | 27 | 1 | 166 |
| α-helix | 29-33 | 5 | |
| β-strand | 42-43 | 2 | 167 |
| α-helix | 44-45 | 2 | |
| α-helix | 46-51 | 6 | |
| α-helix | 58-66 | 9 | |
| β-strand | 70-72 | 3 | 168 |
| β-strand | 75-76 | 2 | 168 |
| β-strand | 83-84 | 2 | 167 |
| β-strand | 90-92 | 3 | 168 |
| β-strand | 97-103 | 7 | 168 |
| β-strand | 109-114 | 6 | 168 |
| α-helix | 116-119 | 4 | |
| β-strand | 122-125 | 4 | 169 |
| β-strand | 126-131 | 6 | 170 |
| α-helix | 133-135 | 3 | |
| β-strand | 137-141 | 5 | 170 |
| β-strand | 146-148 | 3 | 170 |
| β-strand | 159-162 | 4 | 169 |
| β-strand | 169-173 | 5 | 169 |
| β-strand | 180-183 | 4 | 171 |
| β-strand | 193-199 | 7 | 171 |
| β-strand | 207-212 | 6 | 171 |
| β-strand | 217-221 | 5 | 171 |
| β-strand | 225-229 | 5 | 171 |
Chain CB: 8 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 73-75 | 3 | 235 |
| β-strand | 82-85 | 4 | 235 |
| β-strand | 90-95 | 6 | 235 |
| β-strand | 108-111 | 4 | 235 |
| β-strand | 125-129 | 5 | 235 |
| α-helix | 136-143 | 8 | |
| β-strand | 155-159 | 5 | 110 |
| α-helix | 162-164 | 3 | |
| α-helix | 166-174 | 9 | |
| β-strand | 179-184 | 6 | 110 |
| α-helix | 187-199 | 13 | |
| β-strand | 203-207 | 5 | 110 |
| α-helix | 213-215 | 3 | |
| β-strand | 223-228 | 6 | 110 |
| α-helix | 235-246 | 12 | |
| β-strand | 247-258 | 12 | 110 |
| α-helix | 259-262 | 4 | |
| α-helix | 268-281 | 14 | |
| β-strand | 284-291 | 8 | 110 |
| β-strand | 299-306 | 8 | 110 |
Chain Cc: 9 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 18-22 | 5 | |
| β-strand | 28-29 | 2 | 193 |
| β-strand | 33-34 | 2 | 193 |
| α-helix | 70-73 | 4 | |
| α-helix | 76-84 | 9 | |
| α-helix | 88-90 | 3 | |
| α-helix | 94-112 | 19 | |
| α-helix | 116-127 | 12 | |
| β-strand | 131-134 | 4 | 194 |
| β-strand | 145-148 | 4 | 194 |
| α-helix | 151-169 | 19 | |
| α-helix | 177-190 | 14 | |
| α-helix | 196-211 | 16 | |
Chain CC: 22 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 6-10 | 5 | 238 |
| β-strand | 14-20 | 7 | 238 |
| α-helix | 32-39 | 8 | |
| α-helix | 41-43 | 3 | |
| β-strand | 48-55 | 8 | 238 |
| α-helix | 59-71 | 13 | |
| α-helix | 76-85 | 10 | |
| α-helix | 87-88 | 2 | |
| β-strand | 96-100 | 5 | 239 |
| α-helix | 103-112 | 10 | |
| β-strand | 116-120 | 5 | 239 |
| α-helix | 125-136 | 12 | |
| α-helix | 151-166 | 16 | |
| α-helix | 169-171 | 3 | |
| α-helix | 174-203 | 30 | |
| α-helix | 208-212 | 5 | |
| α-helix | 216-226 | 11 | |
| α-helix | 240-243 | 4 | |
| α-helix | 251-259 | 9 | |
| α-helix | 264-267 | 4 | |
| α-helix | 268-302 | 35 | |
| α-helix | 304-309 | 6 | |
| α-helix | 312-322 | 11 | |
| α-helix | 325-330 | 6 | |
| α-helix | 333-338 | 6 | |
| α-helix | 374-394 | 21 | |
| β-strand | 399 | 1 | 240 |
| α-helix | 402-419 | 18 | |
Chain Cd: 5 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-7 | 6 | 203 |
| β-strand | 12-16 | 5 | 203 |
| α-helix | 25-27 | 3 | |
| β-strand | 35-37 | 3 | 203 |
| α-helix | 43-45 | 3 | |
| β-strand | 49-57 | 9 | 203 |
| α-helix | 58-60 | 3 | |
| β-strand | 62 | 1 | 203 |
| β-strand | 63 | 1 | 204 |
| β-strand | 72-77 | 6 | 204 |
| β-strand | 93-98 | 6 | 204 |
| β-strand | 106-115 | 10 | 203 |
| α-helix | 138-145 | 8 | |
| β-strand | 160-162 | 3 | 205 |
| β-strand | 172-174 | 3 | 205 |
| α-helix | 184-225 | 42 | |
Chain CD: 25 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4-5 | 2 | 242 |
| β-strand | 13-15 | 3 | 243 |
| β-strand | 47-49 | 3 | 243 |
| α-helix | 56-66 | 11 | |
| α-helix | 71-77 | 7 | |
| β-strand | 88-89 | 2 | 242 |
| α-helix | 93-99 | 7 | |
| β-strand | 110 | 1 | 242 |
| α-helix | 116-124 | 9 | |
| α-helix | 125-128 | 4 | |
| α-helix | 129-132 | 4 | |
| α-helix | 139-156 | 18 | |
| α-helix | 163-191 | 29 | |
| α-helix | 195-200 | 6 | |
| α-helix | 204-213 | 10 | |
| α-helix | 236-242 | 7 | |
| α-helix | 246-248 | 3 | |
| α-helix | 251-285 | 35 | |
| α-helix | 287-292 | 6 | |
| α-helix | 295-305 | 11 | |
| α-helix | 308-313 | 6 | |
| α-helix | 316-320 | 5 | |
| α-helix | 325-334 | 10 | |
| α-helix | 337-339 | 3 | |
| α-helix | 349-352 | 4 | |
| α-helix | 356-378 | 23 | |
| α-helix | 387-409 | 23 | |
| α-helix | 424-425 | 2 | |
| α-helix | 434-436 | 3 | |
| α-helix | 442-444 | 3 | |
Chain Ce: 6 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 23-34 | 12 | |
| β-strand | 51-56 | 6 | 221 |
| β-strand | 62-68 | 7 | 221 |
| α-helix | 70-78 | 9 | |
| α-helix | 83-90 | 8 | |
| β-strand | 95-100 | 6 | 221 |
| α-helix | 129-139 | 11 | |
| β-strand | 145-152 | 8 | 222 |
| β-strand | 158-164 | 7 | 222 |
| α-helix | 170-172 | 3 | |
| α-helix | 173-187 | 15 | |
| β-strand | 191-194 | 4 | 222 |
57 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Periodic tryptophan protein 2-like protein | UA | protein | 904 | Chaetomium thermophilum | G0SF93 (AlphaFold model) |
| Utp2 | UB | protein | 907 | Chaetomium thermophilum | G0SDW0 (AlphaFold model) |
| Utp3 | UC | protein | 648 | Chaetomium thermophilum | G0S4H3 (AlphaFold model) |
| Utp4 | UD | protein | 884 | Chaetomium thermophilum | G0SCT7 (AlphaFold model) |
| Utp6 | UF | protein | 414 | Chaetomium thermophilum | G0S387 |
| Utp7 | UG | protein | 558 | Chaetomium thermophilum | G0RZ99 |
| UTP10 | UJ | protein | 1802 | Chaetomium thermophilum | G0S5L1 |
| U3 small nucleolar RNA-associated protein 11 | UK | protein | 270 | Chaetomium thermophilum | G0SF32 |
| Utp12 | UL | protein | 962 | Chaetomium thermophilum | G0RZL9 |
| Utp13 | UM | protein | 912 | Chaetomium thermophilum | G0SG95 |
| Utp14 | UN | protein | 938 | Chaetomium thermophilum | G0S8Y4 |
| Utp15 | UO | protein | 557 | Chaetomium thermophilum | G0SEI5 |
51 more molecules are not listed.
Sequence of entity 1 (UA), FASTA
>6RXZ_1 Periodic tryptophan protein 2-like protein (chains UA)
MKTNFKFSNLLGTVYCRGNLLFSPDGTHLFSPVGNRVTVFNLVENKSYTFPFAHRKNISR
IGLTPQGNLLLSIDEDGQAILTNVPRRVVLYHFSFKSPVTALAFSPSGRHFVVGLKRKIE
VWHVPSTPDTNEDGDLEFAPFVRHHTHMQHFDDVRHLEWSSDSRFFLSASKDLTARIWSL
DTEEGFVPTVLSGHRQGVVGAYFSKDQETIYTVSKDGAVFEWKYVAKPGHEDDEMVDDED
MQWRIVNKHFFMQNAATLRCAAYHAESNLLVAGFSNGIFGLYEMPDFNLIHTLSISQNEI
DFVTINKSGEWLAFGASKLGQLLVWEWQSESYILKQQGHFDAMNSLVYSPDGQRIVTAAD
DGKIKVWDVESGFCIVTFTEHTSGVTACEFAKKGSVLFTASLDGSVRAWDLIRYRNFRTF
TAPERLSFTCMAVDPSGEVIAAGSIDSFDIHIWSVQTGQLLDRLSGHEGPVSSLAFAPDG
SVLVSGSWDRTARIWSIFSRTQTSEPLQLQSDVLDVAFRPDSKQIAISTLDGQLTFWSVS
EAQQVSGVDGRRDVSGGRRITDRRTAANVAGTKNFNTIRYSMDGTCLLAGGNSKYICLYS
TTTMVLLKKFTVSVNLSLSGTQEFLNSKLMTEAGPVGLLDDQGEASDLEDRIDRSLPGSK
RGDPGARKKFPEVRVSGVAFSPTGNSFCAASTEGLLVYSLDNTVQFDPFDLNMEITPAST
LAVLEKEKDYLKALVMAFRLNEAGLITRVYQAIPYTDIGLVVEQFPTVYVPRLLRFVAAQ
TEQSPHMEFCLLWIRALIDKHGPWLAANRGKVDVELRVVARAVAKMRDEIRRLADENVYM
VDYLLNQAKSKSNNRAVVGDAEEEWGGLDDFGVKALPSSKPETTLDDIMQDDVAESEEEW
IGLE
Sequence of entity 2 (UB), FASTA
>6RXZ_2 Utp2 (chains UB)
MAGSQLKRLKASLREQGLIGPQKSKKQKRQNANDPKAQEKRLQKAEALKSIREQFNPFQF
KTNARGPKFEVTTNKPTDKNGMVIKGRPELSRARSEEKRRQTILVEMQRRNKVGGIIDRR
FGEGDPNLSVEDKMIERYTQEALRAHKKKGMFDLEDDDEARLTHMGKPLFDDDEAPKEDF
SEDDLPSGDESDTTRAERRALKRQRLAEAMEGLEDEAGQPERKKTRKEIYEEIIAKSKMY
KAERQAIKEENNELRMEVDQELPEVQQLLYQIKKPETEKKEAPVPIIAGKEKTVVDKEYD
IRLKQLAMDKRAQPAEPVKTEEEKAAEAAKKLQELEEKRLKRMRGEPVSDDEESESEEDK
GKKDKKDNAVDPLNAEESEDEFGLGKGVKYKPTATELGLDDEDDFLIDDDLVASGSELEF
DSEDFSDVESDEEEGSSESKEDEEDDEFIKGILTEAEQQEAVFQQPKQGDDENGIPYTFP
CPQSHEEMLNVVKGIEVTKLPTVVQRIRALHHPKLDAKNKERLGNFSQVLIHHIAYLGDR
FQPHWFPTLEQLSRHVHSLAKTFPIEVAKAYRMRIQEMEEHRPLAPTVGDLVILTAIGTT
FPTSDHFHQVCTPAMLAIARYLGQKVPAALSDFAVGIYLSILALQYQDFAKRYVPEMMNF
LLNTLCALAPERAKSKLGNFPVHEPPAGIRIKDATNTPIRQLNCGDCLRKDELSPAETSS
LQIAILSTATAILKSAADTWHKLPAFIESFQPALSVAQHLLTKPNASHLPSSLTSKLNDL
ASHLSRLLQLSRLSRRPLELHHHRPLAIKTYIPKFEDDFDPDKHYDPNRERAELAKLKAE
HKRERKGALRELRKDAQFIRREQLRIKKEKDEAYEKKFKRIIAEIQNEEGRAANEYAREK
AARKRKR
Sequence of entity 3 (UC), FASTA
>6RXZ_3 Utp3 (chains UC)
MAKKRKATRPAEPQGPKEIDPKDARLTVNNYMDVADSEDEYWYKKDRLDIDSDDEPRSKR
LKRQDKEDAFLEQSDEEIFDDELSSEEEEEDDEDERRAPTKKDGKKGAALDDDDDAELLG
LGKKKDDDEIRDEGWWGSSKKEYYNADAIETEQDALEEEKEARRLQAKKLAKMQEADFAF
DEAEWLATKDEKTGGDEEVVTEVLKEVEVTSDMGPEERYNLLQARYPEFDYLVEEFRELR
PLLETLQKEAEGKPAKSLPVVKAWVLGCYVAALASYFAILTSPTRDGDESKGIMNPSELR
DHEVMQTLMECREAWLKVKSLRPAKGAVSAHGMLSPPEEGEEAGSDVDMLDDHAVQKPKK
AKKLSKEEIKANKKKKEEEAKKAKAVEQSLAELTSLLQTTKKAAVKASVASKAMSTAATS
GADSGMDDNRSDFGEEEELDARTAAEKAKRKKSLRFYTSQIVQKANKRQGAGRDAGGDMD
IPYRERLKDRQARLNAEAERRGKRDSKFGADLGGDSSDDEDAKARQVRDDEDAYYNEVVQ
AAAKKRADKQARFEALAAARKGDRVVEEETIGPDGKRQITWQIQKNKGLTPNRKKEQRNP
RVKKRKKYEEKQKKLRSVKAVYKGGEGPGGYQGELSGIKTNLVKSVKL
Sequence of entity 4 (UD), FASTA
>6RXZ_4 Utp4 (chains UD)
MDIHRCRFVRYPASAINAVAFTHSALPVVSSSKKYLQKNIQVRLAIGRANGDIEIWNPLN
GGWYQEVIIPGGKDRSVDGLVWVTDPDEEMADGKIIHGKSRLFSIGYTTTITEWDLEKAR
AKKHASGQHGEIWCFGVQPLPHKANAAAAQNRKLVAGTVDGNLVLYSIEDGDLKFQKTLT
RTPSKKTKFVSIAFQSHNIVIVGCSNSTICAYDVRTGTMLRQMTLGTDLTGGSKNIIVWA
VKCLPNGDIVSGDSTGQVCIWDGKTYTQAQRIQSHTQDVLCLSVSADGSKIISGGMDRRT
AVYEPMAGQSGRWSKVFHRRYHQHDVKAMASFEGKGMSVVVSGGSDASPIVLPLRALGKE
FHRTLPHLPQHPTVLSAPKARYILSWWENEIRIWHLLNSAQQFLDDPQAPLNLRKNRKFL
AQVLIKGASHITSASISEDGTLLAASTPTDVKVFHLDPAAAQRNGQLYIKKVNMTGTGLG
ATRVQISPDKRWICWAEEGSKVMISRVHATESADGISYTVSVPHKLHRLRRQIPKHILLG
GLGSYDRNVSQIAFSADSRMLSVADLAGYIDTWVLRGPGEGVNGTGGEDSDGESAASSSD
SSDEKSEDIAGERWARNPKAAMIPKLSAAPVVLSFSPTPRDDGDYDLLVVTTLKQLLIFN
PLRGMLSEWSRRNTYPKLPEPFRDTRDQVKGIVWQGQRAWFYGVASLFMFDLSQDFSPEK
DLVETNGHKQGTKRKRGAHESGAGSKIEKHSLVPQRIRAASAPDGTKWEDIEMVDADDQK
SVGVSSGVDDDDDETDGSELQRLREENREANSSANAEKEGPSRAKWWHTYQFRPIMGIVP
IEGMMEKKLGAVEGIPPLEVALIERPLSEDDLPERYFAEGEWER
Sequence of entity 5 (UF), FASTA
>6RXZ_5 Utp6 (chains UF)
MAWVADKARFYLERAAPELREWEEKEIFTKDEIRNLVAKRSDFEHLVLAPGTKPTDFLNY
VNWERSLDRLRAKRCARLNIRSVTSHASQARTFGIFERAVLKHPGSIELWLAYLEFAAQV
KATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAHFLRGCRFCTREPTLWLE
YARCEMDWLARMEAKKQGQGVRKGVNALEAIKATEGQEEGDIIPIGEDTEDDSGDEDGLI
LPDPDAEGTDGTKKAAKPVFDAEQTKKLEQSPALSGAIPIAVFDVARKQPFWGPAAAEKF
FDVFAKFGHLSCHERIISHVVTTMQELFPNHPCTWSVHIRQPLVGVDVLTPAFPKALRES
LARLKAALQSTTDRKALATKMVAWMDGILAIEKLDAAIRTVLEHTKRSLEESPS
Sequence of entity 6 (UG), FASTA
>6RXZ_6 Utp7 (chains UG)
MDTSEAVDLAPAPAKQGRQANGAHSIANARTEFRSKAELDRIRRYKQAQKKYGRGPRVDI
KSVRDKKLRRTLTNLENKYKTAALKAKEAEILLENQTGFLEPEGELERTYKVRQDEIVKE
VAVEVAQKKFELKLTELGPYTCEYSRNGRDLILAGRKGHVATMDWREGKLGCELQLGETV
RDARFLHNNQFFAVAQKKYVYIYDHNGVEIHCLRKHVEVSHMEFLPYHFLLATLSISGQL
KYQDTSTGQIVAEIATKHGTPVSLTQNPYNAILHIGQQNGTVTLWSPNSTDPLVKLLAHR
GPVRSLAVDREGRYMVSTGQDNKMCIWDIRNFKEAVNSYFTRAPATSVAISDTGLTAVGW
GTHTTIWKGLFNKERPVQVKVDSPYMTWGGQGQVVERVRWCPFEDILGIGHNEGFSSIIV
PGAGEANYDALEVNPFETKKQRQEGEVKALLNKLQPEMIALDPNFIGNLDLRSEKQRQAE
RDLDQPAQDIVEELRKKARGRNTALKKYLRKQRKKNIIDEKRLKAEELYRQMQEKRDGQT
KEKQAEVGPALARFVRKE
Sequence of entity 7 (UJ), FASTA
>6RXZ_7 UTP10 (chains UJ)
MASSLAQQLAQIAANSRSSFNVKALKASHSKSLIWEPRVAVSQTFAEIYSQCYEGFKELC
HLDSRFVPFDATLFSAQSQEVDRTQMTAEENAALDKRVDSFLHLVGSRLRLMPAIKAVEW
LIRRFRIHEFNTGTLLATFLPYHTIPAFVTLLSILPVQRIPIEYRFLDPYIKSLTPPPRA
AIVQQATNRPDLLSAISRYTLDSCRAKQEYPGLISFWGGIMAEAVNGMIDKMRSGRRAIQ
LENDHLLLQQIGPVLSEAMVMKDVPGIQIASYMVVAILAAKGSLNDNILTAFMEQLVHGW
TVDTLRPGLVCLTMLAQHRSAKQLSGRVAKAVIKVPDLVSSLRDISKEHQVDKLANGLVL
AFVDRLAKKGDIRTLPVINSLLLSELLQEKQAKVAYKALLLAAHKIDDNVDADGNIRKQV
GSALVRLSQAEGDVGDAIRTAIQEVDFNIEELELKLGAAIRPKLAIEEAPEPSDEAMTVR
PVDQRPSLDSTFERLSKLQPTATSCLAKDSESLFNDLCSVFLSAAVSESDLERFDATPVL
SRPKAPSNSFYLSFYLRVWCGPYPTLAKVAALERVKTRLKEGDCVDKDFQAIFPYCIAAL
SDPAKKVRRAAADLVAVLGSAYKSLEKSQQLWAAKDLYGKTGTTSPLDKDALKALIRSVL
IPCLEESVLHEDHVVAALVGALESSKDSENKNADKRHLSHSARLSIFKFLCGHVVETPLL
AVKLRLLRSLNQIRRISGTTRTDLLLPLLRWWAGLSANEAAELAAQESVDVPAIDDAVVD
VVVPNHAAGLEAFFQLVKEAIRPGLLQAIFARIAKMWPSMKSDTKYSTAKTLFELTQDPK
LNAEQSDVITEAVEVLRKVDLTTDILHYFIDSLQDEVRLATEGPANKRRRVSTTEPGRGV
GTQSSPELQAALSKTTFVLELVQESTPANHPELLPSLFTTLSDLHHLSAIVGSELGYLQN
LVLSSLLAMMPTYKDNKDLTIDASVGHGDVLATCIQKSTSPAVINSALLLVASLARTAPD
VVLQSVMPIFTFMGSSVLKQADDYSAHVVNQTIKEVIPPLIETFRKRGRNVVASAKDLLA
SFVTAYEHIPSHRKHNLFISLIQNLGPDDFLFAILAMFVDRYGATDNMITFMTQLISSFT
VETQLQTLLKFLDLVGDLFKSKPTLSNVLLGGGSGLNGEQDIQKAATKQLNLLPHLLSNR
RLKREIMQLAERDDMEAGKIRELYAALLEGILTVASTVKTKKTLHSRCGDALSNLLNLLS
IAEFIKSVEALLDRPNIGLRQKVLRALELRVDSESSVDPKSREALLAFLPQLTAVIRESD
DMNYKHTAVICVDKISEKYGKKDLDAVAAAATTIAGDYCLGQPSQSLRVMALLCLASLVD
VLQDGIVPVLPVAIPKALSYLEQSVAEGGRDVELHNAAYAFMTALAQHIPYMITGNYLDR
LLACSNASAAANLDDEANANRMQCLQFLAKLVDARVLYTGLHQNWASAAKFGFSAISEYL
QILGIALDKHSKTVVVKNVSSLSSIFLSAMDLRRTVAAGDIASQISAMELDEIETKTHED
ALKMVYKLNDAAFRPIFSKFVEWATTGLPKSDVTGRTYRLYVVFGFLDAFFGSLKSIVTG
YASYIVDASVKALKAVDFAVPEERNLWKRVLCTLAKCFEHDQDGFWQAPAHFGAVAPVLV
EQFLRAEGQVTATNVNDVIQDVVPAVVELAAAVESQEHYKEINTALLKHLRNGSPGVRLA
VVKCQQAITAKLGEDWLHLLPEMLPYISELQDDDDEVVERENRRWIVGIEEKLGESLDSM
LQ
Sequence of entity 8 (UK), FASTA
>6RXZ_8 U3 small nucleolar RNA-associated protein 11 (chains UK)
MSSLRHAIQRRAHKERAQPLERQRLGILEKKKDYRLRARDYKKKQAVLKSLRQKAAERNE
DEFYFGMMSRKGPGSALTRGKGFTGTVDGDRGNKALSVETVRLLKTQDLGYVRTMRNIAA
KELKELEERYVLAGGADQPVEEFNSDEDEEESGSKQAKPKKIVFFEGVEERQQALEKQKA
DEEMKDYDEEEDGYDFDDEEEMTEKEKEERRKQLVLEKLARKVKAARKKLKALADAEYEL
ELQQAKMAKTATSGGFTKSGRRIKVRERKR
Sequence of entity 9 (UL), FASTA
>6RXZ_9 Utp12 (chains UL)
MVKSYLKFEPSKSFGVVVSSNSNLVWSSRGKAGAGAGQAIVAANEEVLVWDIKKGELLSR
WRDENCKFRVTAIAQSRTDPDVFAVGYEDGSIRLWDSKIATSVVSFNGHKSAITVLAFDK
TGVRLASGSKDTDIIVWDLVAEVGQYKLRGHKDQVTGLYFIEPDPVVRTEGEDDHAVMAV
DSEPSDGFLLTTGKDSLIKLWDLSSRHCIETHVAQANGECWALGVSPDFTGCITAGNDGE
ITVWALDADALASSAQKVDLSQSVNFLQNRGTLHRSSKERAAEVVFHPLRDYFAVHGVEK
SVEIWRIRNEAEIKKTLARKKKRRREKLKEKKAEGADADMDETDDTDIAKAEVSDVFVQH
VIVRTTGKVRSVDWALNPGVKDLQLLVGGTNNLLELYNIVGKERLKSKGEEPDYNKALAV
ELPGHRTDIRSVAISSDDKMLASAANGSLKIWNIKTQQCIRTFDCGYALCCAFLPGDKVV
IVGTKEGELQLYDVASASLLETVNAHDGHAVWALQVHPDGRSVVSGGADKTAKFWDFKIV
QEPVLGTTRTTHRLKLVQSRILKVSDDILSLRFSPDARLLAVALLDSTVKVFFNDTLKLY
LNLYGHKLPVLSMDISYDSKLIVTSSADKNIRIWGLDFGDCHKALFGHQDSILQVAFIPH
NSDGNGHYFFSASKDRTIKYWDADKFEQIQRIDGHHGEIWALAVSHSGRFLVSASHDKSI
RVWEETDEQIFLEEEREKELEELYEQTLTTSLEQDPDEQDANREIAAATKQTVETLMAGE
RIAEALELGMTDLNTIREWEEARQINPNIAPPQRNPIFVALGNIPAETYVLNTLQKIKPA
SLHDALLVLPFSTIPSLLTFLNLFAQRELNVPLTCRILFFVLKTHHKQIVASRTMRATLE
KVRANLRAALRRQKDEMGFNIAALKVVSMQLRDKSVREYVDETWEEKEKEKGVRKRAFAS
LS
Sequence of entity 10 (UM), FASTA
>6RXZ_10 Utp13 (chains UM)
MATKQPAKTTFEVANVIQPIYTGGSVALENGARILASTLGENAILTELNTGKRLAEIQGD
GEPISTLTITPSGSHLIVCSRSLTMRIYSLAISPDYDSVEPTLVRTTKPHATPVVVLAVD
RTSTLLATGAADGAIKIWDIIGGYVTHTVSGPSVLVSALHFFEIAVTAESQSSNKKPKKG
SRKGQNDDADEIASRFRLAWGTQDGRIRIFDLYKRTTTPVYADPKRKKEAHESNVQCIAY
SPEQHALLSGSRDKTMTLWLWRDGIWQGTPMLRHELLESVGFLNEGKWMYSAGTSGVLRI
WDTTTHHEITKKQDAKSEGEAILSAVSLPERSLILCAQADFTLVLYRVPSPADVVSSSEG
ILLEPFRRISGTHDEILDLTYILPDQSMMAIATNSEDIRIVSVKDAQAYSEDNAECRSGS
YFGHDVALLKGHEDIVMSLDVDWSGHWIASGSKDNTARLWRVDPANNSYTCYAVFTGHLE
SVGAVALPKVVPPANSEAFKNPLDHPPAFLISGSQDRFVQKRDIPRQLQKGGKLTSSLRR
LAHDKDINALDISPNGKLFASASQDKTVKIWDVEKLEVQGILRGHKRGVWTVRFAPLNTP
VIQGEQGSVSGRGVVLTGSGDKTIKLWNLSDYTCIRTFEGHSHNVLKVVWLHISRDDSIT
KTKVQFASAGADTLVKVWDANTGETECTLDNHEDRLWTLAVHSKTNILASAGSDSKVTFW
RDTTAETQAAAAQAALKLVEQEQTLENYIHAGAYRDAIVLALQLNHPGRLLNLFTNVVTT
RNPDPDSLTGLKAVDDVLAKLSDEQIFQLLLRLRDWNTNARTAPVAQRVLWALFKSHPAN
KLSSLSVKGARGHKSLNEVLDAIKVYTERHYKRIEELVDESYLVEYTLREMDALTPQTEA
LEAGEDAVIAEA
Sequence of entity 11 (UN), FASTA
>6RXZ_11 Utp14 (chains UN)
MPGRQAHGRPLLPSLGSSSGGGKSKKSRSKARRSAQSKALDAFALAAEQVPESRSKGVRL
RDLDEHPSTSASRNKRQHEDDEEDDFDGFDDDEGMGRKKRARRDSGGDEDGDDVDEDMEG
GADGEDDSEEWHVGVTGADEDSEIDSDEAFGESDEERFEGFVFGGSKSHKKGTKKRRNGS
EDDAIDLATALDQYESSEEGEEGEESESEEDDEESEEEDSDEEDDDPSKLDALQSMIAGF
AGEDEESGGEGEAKPSGKQKLSLKDLGLVGVKDPDMKRSLRLMKKEEKATKPGSSKKLEV
PLAKRQQDRLMREAAYKKTNETLDRWIETVKHNRRAEHLVFPLAQNAHDRGLDASELQPI
TQKTSGTELEQTILAIMEESGLGPTAKPEKKETSGEAGKQGMSKEEQKELIRQKRREREL
HSREMARLKRIKKIKSKTWRRIHRKELLKNEEAAYQAALEAGELDSEEEREALDRRRALE
RVGARHKESKWAKLGKKAGRAVWDEDFRAGLAEMARRKDELRKRIEGLKNGSDDSSDDSD
GDEDASGDEAAERRKLLAELEKAAAYSDDDEPHSKLFQLKFMQRGEELRRKENEELIAQI
RRELDSDYDGSEPDEVEIGRRTFGMGKKDKTEQQQAQDQLARMQAAEARKEKAAARVAAA
EETVKQEAREKAEKDEASAPSTAGAWSQPKVEAGAWSKPDDEGSSKPRKAPKGRPEEIDV
TDLALAGKPAKAKANGQAKSQVQGKAHASNGQSSSSQKASTSVAITGAEEDGNDSDDSDA
VHLPMAIRDRALIERAFAGDDVAAEFEKEKAEIEADDDEKEIDNTLPGWGSWVGEGVSNR
EKRRHQGRFVTKVEGIKKEKRKDYKLKDVIINEKRVKKNDKYLATGLPHPFESQQQYERS
LRLPVGPEWMTKETFQDATKPRVIIKQGIIAPMSKPMY
Sequence of entity 12 (UO), FASTA
>6RXZ_12 Utp15 (chains UO)
MAAEVVPLPQLKLPSGPSPITAEQRYWRSFKKQKSHTSTANWPISHISFPASLGTTALVS
SSLVAAAKTNDLFAVTAGPRVEIFSIRKREPLKTIGRFDSEAHCGEIRPDGRVLVAGEDT
GRMQVFDVGQGTRAVILKTWHIHKQPVWVTKWSPTELTTLMSCSDDKTVRLWDLPSNDPT
RLFTGHTDYVRCGAFMPGSANSNLLVSGSYDETVRVWDARAPGGAVMTFKHADPIEDVLP
LPSGTTLLAASGNAISVLDLVAAKPLRLITNHQKTVTSLSLASQGRRVVSGSLDGHVKVF
ETTSWNVVAGAKYPSPILSLSVITAGASHDDRHLAVGMQSGVLSIRTRLSGPAADRERER
ERVEAAMAKGPEAIAKLDAAKAKRKRAAVSNKNMDLLGESADVIIPTADPGTHPRGRRPK
LKPWQKAFRQGRYAAAVDDVLNTTAPSYDPVIALTLLTALRHRSALREALQGRDELSVIN
ILRWAGKYVADPRYRSICVDVAFHLIDLYAEHVGGSAELATQFQQLLAKVNREVEKAELA
IVTGGMVESLMMSVEAQ
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 1 |
Primary citation
Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Cheng, J., Bassler, J., Fischer, P. et al. Mol Cell (2019) 75:1256-1269.e7. DOI 10.1016/j.molcel.2019.06.032 · PubMed
Other PDB entries of the same protein (UniProt G0SF93 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9XAG 2.8 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum,…
- 9XA8 2.9 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 WT) from Chaetomium thermophilum,…
- 9XAF 3.0 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum,…
- 9XAH 3.1 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum,…
- 5OQL 3.2 Å, Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum
- 9XA7 3.2 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 WT) from Chaetomium thermophilum,…
- 6RXU 3.5 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 5ICA 3.51 Å, Structure of the CTD complex of UTP12, Utp13, Utp1 and Utp21
- 6RXV 4.0 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXY 4.7 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXT 7.0 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXX 7.1 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
Browse structure collections
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