9XAG: Periodic tryptophan protein 2-like protein
Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum, state B1. Determined by electron microscopy at 2.8 Å resolution. Released 24 Jun 2026.
- Method
- Electron microscopy
- Resolution
- 2.8 Å
- Organism
- Thermochaetoides thermophila
- Chains
- 66
- Atoms
- 227,662
- Mol. weight
- 4490.68 kDa
- Ligands
- GTP, MG, ADP, ZN
- Released
- 24 Jun 2026
Explore 9XAG in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9XAG contains 1,081 α-helices and 1,010 β-strands across 64 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain Ca: 10 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 23-26 | 4 | |
| β-strand | 27-33 | 7 | 158 |
| β-strand | 42-49 | 8 | 158 |
| α-helix | 50-51 | 2 | |
| β-strand | 52 | 1 | 159 |
| β-strand | 55 | 1 | 159 |
| α-helix | 57-60 | 4 | |
| β-strand | 65-69 | 5 | 158 |
| α-helix | 70-74 | 5 | |
| α-helix | 77-79 | 3 | |
| β-strand | 82-91 | 10 | 158 |
| β-strand | 95-105 | 11 | 158 |
| α-helix | 107-113 | 7 | |
| β-strand | 118 | 1 | 160 |
| β-strand | 120-128 | 9 | 158 |
| β-strand | 134-142 | 9 | 158 |
| β-strand | 143 | 1 | 161 |
| β-strand | 154 | 1 | 160 |
| α-helix | 158-177 | 20 | |
| α-helix | 181-188 | 8 | |
| α-helix | 192-201 | 10 | |
| β-strand | 207 | 1 | 161 |
| β-strand | 211-219 | 9 | 158 |
| α-helix | 225-231 | 7 | |
Chain CA: 6 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 67 | 1 | 226 |
| β-strand | 70-75 | 6 | 29 |
| β-strand | 81-86 | 6 | 29 |
| β-strand | 89-95 | 7 | 29 |
| β-strand | 108-111 | 4 | 29 |
| β-strand | 126-129 | 4 | 29 |
| α-helix | 136-143 | 8 | |
| β-strand | 155-159 | 5 | 31 |
| α-helix | 165-174 | 10 | |
| β-strand | 179-184 | 6 | 31 |
| α-helix | 187-199 | 13 | |
| β-strand | 203-207 | 5 | 31 |
| β-strand | 223-228 | 6 | 31 |
| α-helix | 235-246 | 12 | |
| β-strand | 247-258 | 12 | 31 |
| α-helix | 259-262 | 4 | |
| α-helix | 268-281 | 14 | |
| β-strand | 284-291 | 8 | 31 |
| β-strand | 299-306 | 8 | 31 |
Chain Cb: 7 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 9-10 | 2 | 180 |
| β-strand | 27-28 | 2 | 180 |
| α-helix | 29-32 | 4 | |
| α-helix | 38-40 | 3 | |
| α-helix | 44-45 | 2 | |
| α-helix | 46-51 | 6 | |
| α-helix | 58-66 | 9 | |
| β-strand | 71-72 | 2 | 181 |
| β-strand | 75-76 | 2 | 181 |
| β-strand | 88-92 | 5 | 181 |
| β-strand | 97-103 | 7 | 181 |
| β-strand | 109-114 | 6 | 181 |
| α-helix | 116-120 | 5 | |
| β-strand | 122-125 | 4 | 182 |
| β-strand | 126-131 | 6 | 183 |
| β-strand | 137-141 | 5 | 183 |
| β-strand | 145-148 | 4 | 183 |
| β-strand | 159-162 | 4 | 182 |
| β-strand | 169-173 | 5 | 182 |
| β-strand | 180-183 | 4 | 184 |
| α-helix | 186-188 | 3 | |
| β-strand | 191-199 | 9 | 184 |
| β-strand | 207-212 | 6 | 184 |
| β-strand | 216-221 | 6 | 184 |
| β-strand | 225-229 | 5 | 184 |
Chain CB: 9 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 73-75 | 3 | 229 |
| β-strand | 81-85 | 5 | 229 |
| β-strand | 90-95 | 6 | 229 |
| β-strand | 108-111 | 4 | 229 |
| α-helix | 112-113 | 2 | |
| β-strand | 125-129 | 5 | 229 |
| α-helix | 130 | 1 | |
| α-helix | 137-143 | 7 | |
| β-strand | 155-159 | 5 | 103 |
| α-helix | 165-174 | 10 | |
| β-strand | 179-184 | 6 | 103 |
| α-helix | 187-199 | 13 | |
| β-strand | 203-207 | 5 | 103 |
| α-helix | 213-216 | 4 | |
| β-strand | 223-228 | 6 | 103 |
| α-helix | 235-246 | 12 | |
| β-strand | 247-258 | 12 | 103 |
| α-helix | 259-262 | 4 | |
| α-helix | 268-281 | 14 | |
| β-strand | 284-291 | 8 | 103 |
| β-strand | 299-306 | 8 | 103 |
Chain Cc: 8 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 18-22 | 5 | |
| β-strand | 29 | 1 | 193 |
| β-strand | 33 | 1 | 193 |
| β-strand | 50 | 1 | 194 |
| β-strand | 75 | 1 | 194 |
| α-helix | 76-85 | 10 | |
| α-helix | 88-90 | 3 | |
| α-helix | 94-112 | 19 | |
| α-helix | 116-127 | 12 | |
| β-strand | 131-134 | 4 | 195 |
| β-strand | 145-149 | 5 | 195 |
| α-helix | 151-169 | 19 | |
| α-helix | 177-190 | 14 | |
| α-helix | 196-210 | 15 | |
Chain CC: 23 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 6-10 | 5 | 230 |
| β-strand | 14-20 | 7 | 230 |
| α-helix | 32-39 | 8 | |
| α-helix | 41-47 | 7 | |
| β-strand | 48-55 | 8 | 230 |
| α-helix | 59-71 | 13 | |
| α-helix | 76-85 | 10 | |
| α-helix | 87-88 | 2 | |
| β-strand | 96-100 | 5 | 230 |
| α-helix | 103-112 | 10 | |
| β-strand | 116-120 | 5 | 230 |
| α-helix | 125-136 | 12 | |
| α-helix | 138-141 | 4 | |
| α-helix | 150-166 | 17 | |
| α-helix | 168-171 | 4 | |
| α-helix | 175-205 | 31 | |
| α-helix | 209-212 | 4 | |
| α-helix | 216-226 | 11 | |
| α-helix | 240-243 | 4 | |
| α-helix | 251-260 | 10 | |
| α-helix | 263-265 | 3 | |
| α-helix | 268-302 | 35 | |
| α-helix | 304-310 | 7 | |
| α-helix | 312-322 | 11 | |
| α-helix | 325-330 | 6 | |
| α-helix | 333-338 | 6 | |
| α-helix | 373-395 | 23 | |
| α-helix | 401-419 | 19 | |
Chain Cd: 6 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-7 | 6 | 213 |
| β-strand | 12-17 | 6 | 213 |
| α-helix | 21-24 | 4 | |
| β-strand | 34-37 | 4 | 213 |
| α-helix | 43-45 | 3 | |
| β-strand | 49-57 | 9 | 213 |
| α-helix | 61 | 1 | |
| β-strand | 62 | 1 | 213 |
| β-strand | 63 | 1 | 214 |
| β-strand | 72-77 | 6 | 214 |
| β-strand | 93-98 | 6 | 214 |
| β-strand | 106-115 | 10 | 213 |
| α-helix | 138-145 | 8 | |
| β-strand | 160-162 | 3 | 215 |
| α-helix | 169-171 | 3 | |
| β-strand | 172-174 | 3 | 215 |
| α-helix | 184-225 | 42 | |
Chain CD: 28 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 3-8 | 6 | 231 |
| β-strand | 12-18 | 7 | 231 |
| α-helix | 29-32 | 4 | |
| α-helix | 36-42 | 7 | |
| β-strand | 43-50 | 8 | 231 |
| α-helix | 54-66 | 13 | |
| α-helix | 71-80 | 10 | |
| β-strand | 86-89 | 4 | 231 |
| α-helix | 93-100 | 8 | |
| β-strand | 107-110 | 4 | 231 |
| α-helix | 116-125 | 10 | |
| α-helix | 126-128 | 3 | |
| α-helix | 135-154 | 20 | |
| α-helix | 163-191 | 29 | |
| α-helix | 196-200 | 5 | |
| α-helix | 204-213 | 10 | |
| α-helix | 233-242 | 10 | |
| α-helix | 251-285 | 35 | |
| α-helix | 287-292 | 6 | |
| α-helix | 295-305 | 11 | |
| α-helix | 308-313 | 6 | |
| α-helix | 316-320 | 5 | |
| α-helix | 325-334 | 10 | |
| α-helix | 337-339 | 3 | |
| α-helix | 343-345 | 3 | |
| α-helix | 348-352 | 5 | |
| α-helix | 356-378 | 23 | |
| α-helix | 387-390 | 4 | |
| α-helix | 392-409 | 18 | |
| α-helix | 411-415 | 5 | |
| β-strand | 419 | 1 | 232 |
| β-strand | 425 | 1 | 232 |
| α-helix | 428-432 | 5 | |
| α-helix | 434-436 | 3 | |
| α-helix | 442-444 | 3 | |
56 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Periodic tryptophan protein 2-like protein | UA | protein | 904 | Thermochaetoides thermophila | G0SF93 (AlphaFold model) |
| Nucleolar complex protein 14 | UB | protein | 907 | Thermochaetoides thermophila | G0SDW0 (AlphaFold model) |
| Sas10 C-terminal domain-containing protein | UC | protein | 648 | Thermochaetoides thermophila | G0S4H3 (AlphaFold model) |
| UTP4 | UD | protein | 884 | Thermochaetoides thermophila | G0SCT7 (AlphaFold model) |
| U3 snoRNP protein | UF | protein | 414 | Thermochaetoides thermophila | G0S387 |
| U three protein 7 | UG | protein | 558 | Thermochaetoides thermophila | G0RZ99 |
| U3 small nucleolar RNA-associated protein 10 | UJ | protein | 1802 | Thermochaetoides thermophila | G0S5L1 |
| U3 small nucleolar RNA-associated protein 11 | UK | protein | 270 | Thermochaetoides thermophila | G0SF32 |
| Small-subunit processome Utp12 domain-containing protein | UL | protein | 962 | Thermochaetoides thermophila | G0RZL9 |
| U3 small nucleolar RNA-associated protein 13 C-terminal domain-containing protein | UM | protein | 912 | Thermochaetoides thermophila | G0SG95 |
| UTP14 | UN | protein | 716 | Thermochaetoides thermophila | |
| U3 small nucleolar RNA-associated protein 15 C-terminal domain-containing protein | UO | protein | 557 | Thermochaetoides thermophila | G0SEI5 |
49 more molecules are not listed.
Sequence of entity 1 (UA), FASTA
>9XAG_1 Periodic tryptophan protein 2-like protein (chains UA)
MKTNFKFSNLLGTVYCRGNLLFSPDGTHLFSPVGNRVTVFNLVENKSYTFPFAHRKNISR
IGLTPQGNLLLSIDEDGQAILTNVPRRVVLYHFSFKSPVTALAFSPSGRHFVVGLKRKIE
VWHVPSTPDTNEDGDLEFAPFVRHHTHMQHFDDVRHLEWSSDSRFFLSASKDLTARIWSL
DTEEGFVPTVLSGHRQGVVGAYFSKDQETIYTVSKDGAVFEWKYVAKPGHEDDEMVDDED
MQWRIVNKHFFMQNAATLRCAAYHAESNLLVAGFSNGIFGLYEMPDFNLIHTLSISQNEI
DFVTINKSGEWLAFGASKLGQLLVWEWQSESYILKQQGHFDAMNSLVYSPDGQRIVTAAD
DGKIKVWDVESGFCIVTFTEHTSGVTACEFAKKGSVLFTASLDGSVRAWDLIRYRNFRTF
TAPERLSFTCMAVDPSGEVIAAGSIDSFDIHIWSVQTGQLLDRLSGHEGPVSSLAFAPDG
SVLVSGSWDRTARIWSIFSRTQTSEPLQLQSDVLDVAFRPDSKQIAISTLDGQLTFWSVS
EAQQVSGVDGRRDVSGGRRITDRRTAANVAGTKNFNTIRYSMDGTCLLAGGNSKYICLYS
TTTMVLLKKFTVSVNLSLSGTQEFLNSKLMTEAGPVGLLDDQGEASDLEDRIDRSLPGSK
RGDPGARKKFPEVRVSGVAFSPTGNSFCAASTEGLLVYSLDNTVQFDPFDLNMEITPAST
LAVLEKEKDYLKALVMAFRLNEAGLITRVYQAIPYTDIGLVVEQFPTVYVPRLLRFVAAQ
TEQSPHMEFCLLWIRALIDKHGPWLAANRGKVDVELRVVARAVAKMRDEIRRLADENVYM
VDYLLNQAKSKSNNRAVVGDAEEEWGGLDDFGVKALPSSKPETTLDDIMQDDVAESEEEW
IGLE
Sequence of entity 2 (UB), FASTA
>9XAG_2 Nucleolar complex protein 14 (chains UB)
MAGSQLKRLKASLREQGLIGPQKSKKQKRQNANDPKAQEKRLQKAEALKSIREQFNPFQF
KTNARGPKFEVTTNKPTDKNGMVIKGRPELSRARSEEKRRQTILVEMQRRNKVGGIIDRR
FGEGDPNLSVEDKMIERYTQEALRAHKKKGMFDLEDDDEARLTHMGKPLFDDDEAPKEDF
SEDDLPSGDESDTTRAERRALKRQRLAEAMEGLEDEAGQPERKKTRKEIYEEIIAKSKMY
KAERQAIKEENNELRMEVDQELPEVQQLLYQIKKPETEKKEAPVPIIAGKEKTVVDKEYD
IRLKQLAMDKRAQPAEPVKTEEEKAAEAAKKLQELEEKRLKRMRGEPVSDDEESESEEDK
GKKDKKDNAVDPLNAEESEDEFGLGKGVKYKPTATELGLDDEDDFLIDDDLVASGSELEF
DSEDFSDVESDEEEGSSESKEDEEDDEFIKGILTEAEQQEAVFQQPKQGDDENGIPYTFP
CPQSHEEMLNVVKGIEVTKLPTVVQRIRALHHPKLDAKNKERLGNFSQVLIHHIAYLGDR
FQPHWFPTLEQLSRHVHSLAKTFPIEVAKAYRMRIQEMEEHRPLAPTVGDLVILTAIGTT
FPTSDHFHQVCTPAMLAIARYLGQKVPAALSDFAVGIYLSILALQYQDFAKRYVPEMMNF
LLNTLCALAPERAKSKLGNFPVHEPPAGIRIKDATNTPIRQLNCGDCLRKDELSPAETSS
LQIAILSTATAILKSAADTWHKLPAFIESFQPALSVAQHLLTKPNASHLPSSLTSKLNDL
ASHLSRLLQLSRLSRRPLELHHHRPLAIKTYIPKFEDDFDPDKHYDPNRERAELAKLKAE
HKRERKGALRELRKDAQFIRREQLRIKKEKDEAYEKKFKRIIAEIQNEEGRAANEYAREK
AARKRKR
Sequence of entity 3 (UC), FASTA
>9XAG_3 Sas10 C-terminal domain-containing protein (chains UC)
MAKKRKATRPAEPQGPKEIDPKDARLTVNNYMDVADSEDEYWYKKDRLDIDSDDEPRSKR
LKRQDKEDAFLEQSDEEIFDDELSSEEEEEDDEDERRAPTKKDGKKGAALDDDDDAELLG
LGKKKDDDEIRDEGWWGSSKKEYYNADAIETEQDALEEEKEARRLQAKKLAKMQEADFAF
DEAEWLATKDEKTGGDEEVVTEVLKEVEVTSDMGPEERYNLLQARYPEFDYLVEEFRELR
PLLETLQKEAEGKPAKSLPVVKAWVLGCYVAALASYFAILTSPTRDGDESKGIMNPSELR
DHEVMQTLMECREAWLKVKSLRPAKGAVSAHGMLSPPEEGEEAGSDVDMLDDHAVQKPKK
AKKLSKEEIKANKKKKEEEAKKAKAVEQSLAELTSLLQTTKKAAVKASVASKAMSTAATS
GADSGMDDNRSDFGEEEELDARTAAEKAKRKKSLRFYTSQIVQKANKRQGAGRDAGGDMD
IPYRERLKDRQARLNAEAERRGKRDSKFGADLGGDSSDDEDAKARQVRDDEDAYYNEVVQ
AAAKKRADKQARFEALAAARKGDRVVEEETIGPDGKRQITWQIQKNKGLTPNRKKEQRNP
RVKKRKKYEEKQKKLRSVKAVYKGGEGPGGYQGELSGIKTNLVKSVKL
Sequence of entity 4 (UD), FASTA
>9XAG_4 UTP4 (chains UD)
MDIHRCRFVRYPASAINAVAFTHSALPVVSSSKKYLQKNIQVRLAIGRANGDIEIWNPLN
GGWYQEVIIPGGKDRSVDGLVWVTDPDEEMADGKIIHGKSRLFSIGYTTTITEWDLEKAR
AKKHASGQHGEIWCFGVQPLPHKANAAAAQNRKLVAGTVDGNLVLYSIEDGDLKFQKTLT
RTPSKKTKFVSIAFQSHNIVIVGCSNSTICAYDVRTGTMLRQMTLGTDLTGGSKNIIVWA
VKCLPNGDIVSGDSTGQVCIWDGKTYTQAQRIQSHTQDVLCLSVSADGSKIISGGMDRRT
AVYEPMAGQSGRWSKVFHRRYHQHDVKAMASFEGKGMSVVVSGGSDASPIVLPLRALGKE
FHRTLPHLPQHPTVLSAPKARYILSWWENEIRIWHLLNSAQQFLDDPQAPLNLRKNRKFL
AQVLIKGASHITSASISEDGTLLAASTPTDVKVFHLDPAAAQRNGQLYIKKVNMTGTGLG
ATRVQISPDKRWICWAEEGSKVMISRVHATESADGISYTVSVPHKLHRLRRQIPKHILLG
GLGSYDRNVSQIAFSADSRMLSVADLAGYIDTWVLRGPGEGVNGTGGEDSDGESAASSSD
SSDEKSEDIAGERWARNPKAAMIPKLSAAPVVLSFSPTPRDDGDYDLLVVTTLKQLLIFN
PLRGMLSEWSRRNTYPKLPEPFRDTRDQVKGIVWQGQRAWFYGVASLFMFDLSQDFSPEK
DLVETNGHKQGTKRKRGAHESGAGSKIEKHSLVPQRIRAASAPDGTKWEDIEMVDADDQK
SVGVSSGVDDDDDETDGSELQRLREENREANSSANAEKEGPSRAKWWHTYQFRPIMGIVP
IEGMMEKKLGAVEGIPPLEVALIERPLSEDDLPERYFAEGEWER
Sequence of entity 5 (UF), FASTA
>9XAG_5 U3 snoRNP protein (chains UF)
MAWVADKARFYLERAAPELREWEEKEIFTKDEIRNLVAKRSDFEHLVLAPGTKPTDFLNY
VNWERSLDRLRAKRCARLNIRSVTSHASQARTFGIFERAVLKHPGSIELWLAYLEFAAQV
KATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAHFLRGCRFCTREPTLWLE
YARCEMDWLARMEAKKQGQGVRKGVNALEAIKATEGQEEGDIIPIGEDTEDDSGDEDGLI
LPDPDAEGTDGTKKAAKPVFDAEQTKKLEQSPALSGAIPIAVFDVARKQPFWGPAAAEKF
FDVFAKFGHLSCHERIISHVVTTMQELFPNHPCTWSVHIRQPLVGVDVLTPAFPKALRES
LARLKAALQSTTDRKALATKMVAWMDGILAIEKLDAAIRTVLEHTKRSLEESPS
Sequence of entity 6 (UG), FASTA
>9XAG_6 U three protein 7 (chains UG)
MDTSEAVDLAPAPAKQGRQANGAHSIANARTEFRSKAELDRIRRYKQAQKKYGRGPRVDI
KSVRDKKLRRTLTNLENKYKTAALKAKEAEILLENQTGFLEPEGELERTYKVRQDEIVKE
VAVEVAQKKFELKLTELGPYTCEYSRNGRDLILAGRKGHVATMDWREGKLGCELQLGETV
RDARFLHNNQFFAVAQKKYVYIYDHNGVEIHCLRKHVEVSHMEFLPYHFLLATLSISGQL
KYQDTSTGQIVAEIATKHGTPVSLTQNPYNAILHIGQQNGTVTLWSPNSTDPLVKLLAHR
GPVRSLAVDREGRYMVSTGQDNKMCIWDIRNFKEAVNSYFTRAPATSVAISDTGLTAVGW
GTHTTIWKGLFNKERPVQVKVDSPYMTWGGQGQVVERVRWCPFEDILGIGHNEGFSSIIV
PGAGEANYDALEVNPFETKKQRQEGEVKALLNKLQPEMIALDPNFIGNLDLRSEKQRQAE
RDLDQPAQDIVEELRKKARGRNTALKKYLRKQRKKNIIDEKRLKAEELYRQMQEKRDGQT
KEKQAEVGPALARFVRKE
Sequence of entity 7 (UJ), FASTA
>9XAG_7 U3 small nucleolar RNA-associated protein 10 (chains UJ)
MASSLAQQLAQIAANSRSSFNVKALKASHSKSLIWEPRVAVSQTFAEIYSQCYEGFKELC
HLDSRFVPFDATLFSAQSQEVDRTQMTAEENAALDKRVDSFLHLVGSRLRLMPAIKAVEW
LIRRFRIHEFNTGTLLATFLPYHTIPAFVTLLSILPVQRIPIEYRFLDPYIKSLTPPPRA
AIVQQATNRPDLLSAISRYTLDSCRAKQEYPGLISFWGGIMAEAVNGMIDKMRSGRRAIQ
LENDHLLLQQIGPVLSEAMVMKDVPGIQIASYMVVAILAAKGSLNDNILTAFMEQLVHGW
TVDTLRPGLVCLTMLAQHRSAKQLSGRVAKAVIKVPDLVSSLRDISKEHQVDKLANGLVL
AFVDRLAKKGDIRTLPVINSLLLSELLQEKQAKVAYKALLLAAHKIDDNVDADGNIRKQV
GSALVRLSQAEGDVGDAIRTAIQEVDFNIEELELKLGAAIRPKLAIEEAPEPSDEAMTVR
PVDQRPSLDSTFERLSKLQPTATSCLAKDSESLFNDLCSVFLSAAVSESDLERFDATPVL
SRPKAPSNSFYLSFYLRVWCGPYPTLAKVAALERVKTRLKEGDCVDKDFQAIFPYCIAAL
SDPAKKVRRAAADLVAVLGSAYKSLEKSQQLWAAKDLYGKTGTTSPLDKDALKALIRSVL
IPCLEESVLHEDHVVAALVGALESSKDSENKNADKRHLSHSARLSIFKFLCGHVVETPLL
AVKLRLLRSLNQIRRISGTTRTDLLLPLLRWWAGLSANEAAELAAQESVDVPAIDDAVVD
VVVPNHAAGLEAFFQLVKEAIRPGLLQAIFARIAKMWPSMKSDTKYSTAKTLFELTQDPK
LNAEQSDVITEAVEVLRKVDLTTDILHYFIDSLQDEVRLATEGPANKRRRVSTTEPGRGV
GTQSSPELQAALSKTTFVLELVQESTPANHPELLPSLFTTLSDLHHLSAIVGSELGYLQN
LVLSSLLAMMPTYKDNKDLTIDASVGHGDVLATCIQKSTSPAVINSALLLVASLARTAPD
VVLQSVMPIFTFMGSSVLKQADDYSAHVVNQTIKEVIPPLIETFRKRGRNVVASAKDLLA
SFVTAYEHIPSHRKHNLFISLIQNLGPDDFLFAILAMFVDRYGATDNMITFMTQLISSFT
VETQLQTLLKFLDLVGDLFKSKPTLSNVLLGGGSGLNGEQDIQKAATKQLNLLPHLLSNR
RLKREIMQLAERDDMEAGKIRELYAALLEGILTVASTVKTKKTLHSRCGDALSNLLNLLS
IAEFIKSVEALLDRPNIGLRQKVLRALELRVDSESSVDPKSREALLAFLPQLTAVIRESD
DMNYKHTAVICVDKISEKYGKKDLDAVAAAATTIAGDYCLGQPSQSLRVMALLCLASLVD
VLQDGIVPVLPVAIPKALSYLEQSVAEGGRDVELHNAAYAFMTALAQHIPYMITGNYLDR
LLACSNASAAANLDDEANANRMQCLQFLAKLVDARVLYTGLHQNWASAAKFGFSAISEYL
QILGIALDKHSKTVVVKNVSSLSSIFLSAMDLRRTVAAGDIASQISAMELDEIETKTHED
ALKMVYKLNDAAFRPIFSKFVEWATTGLPKSDVTGRTYRLYVVFGFLDAFFGSLKSIVTG
YASYIVDASVKALKAVDFAVPEERNLWKRVLCTLAKCFEHDQDGFWQAPAHFGAVAPVLV
EQFLRAEGQVTATNVNDVIQDVVPAVVELAAAVESQEHYKEINTALLKHLRNGSPGVRLA
VVKCQQAITAKLGEDWLHLLPEMLPYISELQDDDDEVVERENRRWIVGIEEKLGESLDSM
LQ
Sequence of entity 8 (UK), FASTA
>9XAG_8 U3 small nucleolar RNA-associated protein 11 (chains UK)
MSSLRHAIQRRAHKERAQPLERQRLGILEKKKDYRLRARDYKKKQAVLKSLRQKAAERNE
DEFYFGMMSRKGPGSALTRGKGFTGTVDGDRGNKALSVETVRLLKTQDLGYVRTMRNIAA
KELKELEERYVLAGGADQPVEEFNSDEDEEESGSKQAKPKKIVFFEGVEERQQALEKQKA
DEEMKDYDEEEDGYDFDDEEEMTEKEKEERRKQLVLEKLARKVKAARKKLKALADAEYEL
ELQQAKMAKTATSGGFTKSGRRIKVRERKR
Sequence of entity 9 (UL), FASTA
>9XAG_9 Small-subunit processome Utp12 domain-containing protein (chains UL)
MVKSYLKFEPSKSFGVVVSSNSNLVWSSRGKAGAGAGQAIVAANEEVLVWDIKKGELLSR
WRDENCKFRVTAIAQSRTDPDVFAVGYEDGSIRLWDSKIATSVVSFNGHKSAITVLAFDK
TGVRLASGSKDTDIIVWDLVAEVGQYKLRGHKDQVTGLYFIEPDPVVRTEGEDDHAVMAV
DSEPSDGFLLTTGKDSLIKLWDLSSRHCIETHVAQANGECWALGVSPDFTGCITAGNDGE
ITVWALDADALASSAQKVDLSQSVNFLQNRGTLHRSSKERAAEVVFHPLRDYFAVHGVEK
SVEIWRIRNEAEIKKTLARKKKRRREKLKEKKAEGADADMDETDDTDIAKAEVSDVFVQH
VIVRTTGKVRSVDWALNPGVKDLQLLVGGTNNLLELYNIVGKERLKSKGEEPDYNKALAV
ELPGHRTDIRSVAISSDDKMLASAANGSLKIWNIKTQQCIRTFDCGYALCCAFLPGDKVV
IVGTKEGELQLYDVASASLLETVNAHDGHAVWALQVHPDGRSVVSGGADKTAKFWDFKIV
QEPVLGTTRTTHRLKLVQSRILKVSDDILSLRFSPDARLLAVALLDSTVKVFFNDTLKLY
LNLYGHKLPVLSMDISYDSKLIVTSSADKNIRIWGLDFGDCHKALFGHQDSILQVAFIPH
NSDGNGHYFFSASKDRTIKYWDADKFEQIQRIDGHHGEIWALAVSHSGRFLVSASHDKSI
RVWEETDEQIFLEEEREKELEELYEQTLTTSLEQDPDEQDANREIAAATKQTVETLMAGE
RIAEALELGMTDLNTIREWEEARQINPNIAPPQRNPIFVALGNIPAETYVLNTLQKIKPA
SLHDALLVLPFSTIPSLLTFLNLFAQRELNVPLTCRILFFVLKTHHKQIVASRTMRATLE
KVRANLRAALRRQKDEMGFNIAALKVVSMQLRDKSVREYVDETWEEKEKEKGVRKRAFAS
LS
Sequence of entity 10 (UM), FASTA
>9XAG_10 U3 small nucleolar RNA-associated protein 13 C-terminal domain-containing protein (chains UM)
MATKQPAKTTFEVANVIQPIYTGGSVALENGARILASTLGENAILTELNTGKRLAEIQGD
GEPISTLTITPSGSHLIVCSRSLTMRIYSLAISPDYDSVEPTLVRTTKPHATPVVVLAVD
RTSTLLATGAADGAIKIWDIIGGYVTHTVSGPSVLVSALHFFEIAVTAESQSSNKKPKKG
SRKGQNDDADEIASRFRLAWGTQDGRIRIFDLYKRTTTPVYADPKRKKEAHESNVQCIAY
SPEQHALLSGSRDKTMTLWLWRDGIWQGTPMLRHELLESVGFLNEGKWMYSAGTSGVLRI
WDTTTHHEITKKQDAKSEGEAILSAVSLPERSLILCAQADFTLVLYRVPSPADVVSSSEG
ILLEPFRRISGTHDEILDLTYILPDQSMMAIATNSEDIRIVSVKDAQAYSEDNAECRSGS
YFGHDVALLKGHEDIVMSLDVDWSGHWIASGSKDNTARLWRVDPANNSYTCYAVFTGHLE
SVGAVALPKVVPPANSEAFKNPLDHPPAFLISGSQDRFVQKRDIPRQLQKGGKLTSSLRR
LAHDKDINALDISPNGKLFASASQDKTVKIWDVEKLEVQGILRGHKRGVWTVRFAPLNTP
VIQGEQGSVSGRGVVLTGSGDKTIKLWNLSDYTCIRTFEGHSHNVLKVVWLHISRDDSIT
KTKVQFASAGADTLVKVWDANTGETECTLDNHEDRLWTLAVHSKTNILASAGSDSKVTFW
RDTTAETQAAAAQAALKLVEQEQTLENYIHAGAYRDAIVLALQLNHPGRLLNLFTNVVTT
RNPDPDSLTGLKAVDDVLAKLSDEQIFQLLLRLRDWNTNARTAPVAQRVLWALFKSHPAN
KLSSLSVKGARGHKSLNEVLDAIKVYTERHYKRIEELVDESYLVEYTLREMDALTPQTEA
LEAGEDAVIAEA
Sequence of entity 11 (UN), FASTA
>9XAG_11 UTP14 (chains UN)
MPGRQAHGRPLLPSLGSSSGGGKSKKSRSKARRSAQSKALDAFALAAEQVPESRSKGVRL
RDLDEHPSTSASRNKRQHEDDEEDDFDGFDDDEGMGRKKRARRDSGGDEDGDDVDEDMEG
GADGEDDSEEWHVGVTGADEDSEIDSDEAFGESDEERFEGFVFGGSKSHKKGTKKRRNGS
EDDAIDLATALDQYESSEEGEEGEESESEEDDEESEEEDSDEEDDDPSKLDALQSMIAGF
AGEDEESGGEGEAKPSGKQKLSLKDLGLVGVKDPDMKRSLRLMKKEEKATKPGSSKKLEV
PLAKRQQDRLMREAAYKKTNETLDRWIETVKHNRRAEHLVFPLAQNAHDRGLDASELQPI
TQKTSGTELEQTILAIMEESELDSDYDGSEPDEVEIGRRTFGMGKKDKTEQQQAQDQLAR
MQAAEARKEKAAARVAAAEETVKQEAREKAEKDEASAPSTAGAWSQPKVEAGAWSKPDDE
GSSKPRKAPKGRPEEIDVTDLALAGKPAKAKANGQAKSQVQGKAHASNGQSSSSQKASTS
VAITGAEEDGNDSDDSDAVHLPMAIRDRALIERAFAGDDVAAEFEKEKAEIEADDDEKEI
DNTLPGWGSWVGEGVSNREKRRHQGRFVTKVEGIKKEKRKDYKLKDVIINEKRVKKNDKY
LATGLPHPFESQQQYERSLRLPVGPEWMTKETFQDATKPRVIIKQGIIAPMSKPMY
Sequence of entity 12 (UO), FASTA
>9XAG_12 U3 small nucleolar RNA-associated protein 15 C-terminal domain-containing protein (chains UO)
MAAEVVPLPQLKLPSGPSPITAEQRYWRSFKKQKSHTSTANWPISHISFPASLGTTALVS
SSLVAAAKTNDLFAVTAGPRVEIFSIRKREPLKTIGRFDSEAHCGEIRPDGRVLVAGEDT
GRMQVFDVGQGTRAVILKTWHIHKQPVWVTKWSPTELTTLMSCSDDKTVRLWDLPSNDPT
RLFTGHTDYVRCGAFMPGSANSNLLVSGSYDETVRVWDARAPGGAVMTFKHADPIEDVLP
LPSGTTLLAASGNAISVLDLVAAKPLRLITNHQKTVTSLSLASQGRRVVSGSLDGHVKVF
ETTSWNVVAGAKYPSPILSLSVITAGASHDDRHLAVGMQSGVLSIRTRLSGPAADRERER
ERVEAAMAKGPEAIAKLDAAKAKRKRAAVSNKNMDLLGESADVIIPTADPGTHPRGRRPK
LKPWQKAFRQGRYAAAVDDVLNTTAPSYDPVIALTLLTALRHRSALREALQGRDELSVIN
ILRWAGKYVADPRYRSICVDVAFHLIDLYAEHVGGSAELATQFQQLLAKVNREVEKAELA
IVTGGMVESLMMSVEAQ
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 1 |
| MG | Magnesium ion | Mg | 1 |
| ADP | Adenosine-5'-diphosphate | C10 H15 N5 O10 P2 | 1 |
| ZN | Zinc ion | Zn | 1 |
Primary citation
Nucleoplasmic checkpoint of the 40S ribosomal decoding center maturation. Lau, B., Li, Y., Zhu, J. et al. Cell Rep (2026) 45:117545-117545. DOI 10.1016/j.celrep.2026.117545 · PubMed
Other PDB entries of the same protein (UniProt G0SF93 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 9XA8 2.9 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 WT) from Chaetomium thermophilum,…
- 9XAF 3.0 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum,…
- 9XAH 3.1 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 Mut) from Chaetomium thermophilum,…
- 5OQL 3.2 Å, Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum
- 9XA7 3.2 Å, Cryo-EM structure of the 90S pre-ribosome (Enp1-Rrp12 WT) from Chaetomium thermophilum,…
- 6RXU 3.5 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 5ICA 3.51 Å, Structure of the CTD complex of UTP12, Utp13, Utp1 and Utp21
- 6RXV 4.0 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXZ 4.4 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXY 4.7 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXT 7.0 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
- 6RXX 7.1 Å, Cryo-EM structure of the 90S pre-ribosome (Kre33-Noc4) from Chaetomium thermophilum,…
Browse structure collections
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