7ABG: Human pre-Bact-1 spliceosome

Human pre-Bact-1 spliceosome. Determined by electron microscopy at 7.8 Å resolution. Released 23 Dec 2020.

Method: Electron microscopy
Resolution: 7.8 Å
Organisms: Homo sapiens, synthetic construct
Chains: 58
Atoms: 73,818
Mol. weight: 2762.07 kDa
Ligands: IHP, GTP, MG, GTG
Released: 23 Dec 2020

Explore 7ABG in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7ABG contains 534 α-helices and 507 β-strands across 54 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 0: 1 helix, 9 β-strands

Element	Residues	Length	Sheet
α-helix	230-236	7
β-strand	238	1	79
β-strand	243	1	79
β-strand	252	1	80
β-strand	261	1	81
β-strand	263-264	2	82
β-strand	273	1	81
β-strand	307-314	8	80
β-strand	320-327	8	80
β-strand	368-369	2	82

Chain 4: 24 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	3-7	5
α-helix	8-27	20
α-helix	33-58	26
α-helix	62-72	11
α-helix	79-87	9
α-helix	103-108	6
β-strand	112	1	11
β-strand	115	1	11
α-helix	119-121	3
α-helix	126-128	3
α-helix	132-134	3
α-helix	143-153	11
α-helix	160-167	8
α-helix	182-199	18
α-helix	206-219	14
α-helix	221-223	3
β-strand	284	1	12
β-strand	289	1	12
α-helix	294-300	7
α-helix	304-307	4
α-helix	318-333	16
α-helix	335-350	16
α-helix	353-361	9
α-helix	394-400	7
β-strand	406-408	3	13
β-strand	414-416	3	13
α-helix	419-426	8
α-helix	429-438	10
α-helix	452-462	11
α-helix	489-498	10

Chain 9: 2 helices, 5 β-strands

Element	Residues	Length	Sheet
α-helix	22-24	3
β-strand	28-33	6	7
β-strand	37-46	10	7
β-strand	52-63	12	7
β-strand	76-87	12	7
α-helix	89-91	3
β-strand	92-96	5	7

Chain a: 1 helix, 5 β-strands

Element	Residues	Length	Sheet
α-helix	27-37	11
β-strand	42-46	5	6
β-strand	51-59	9	6
β-strand	65-73	9	6
β-strand	93-101	9	6
β-strand	106-110	5	6

Chain A: 91 helices, 57 β-strands

Element	Residues	Length	Sheet
α-helix	65-69	5
α-helix	85-94	10
α-helix	98-102	5
α-helix	109-111	3
β-strand	117-120	4	114
β-strand	127-128	2	114
α-helix	131-133	3
α-helix	137-157	21
α-helix	234-243	10
α-helix	260-269	10
α-helix	310-315	6
α-helix	317-320	4
α-helix	370-371	2
α-helix	374-378	5
α-helix	399-403	5
α-helix	404-406	3
α-helix	428-431	4
α-helix	441-459	19
α-helix	476-478	3
β-strand	483-486	4	114
α-helix	489-510	22
β-strand	516-517	2	115
β-strand	525-526	2	115
α-helix	535-537	3
α-helix	544-565	22
α-helix	573-586	14
α-helix	591-594	4
α-helix	598-616	19
α-helix	633-657	25
α-helix	678-695	18
α-helix	708-721	14
α-helix	733-759	27
α-helix	771-796	26
α-helix	803-820	18
β-strand	825	1	116
α-helix	835-850	16
α-helix	860-872	13
α-helix	874-887	14
α-helix	893-894	2
β-strand	895-899	5	117
β-strand	906-910	5	117
α-helix	913-933	21
β-strand	940	1	118
α-helix	947-960	14
β-strand	973-980	8	118
α-helix	990-1000	11
β-strand	1001	1	116
α-helix	1003-1012	10
β-strand	1018	1	117
α-helix	1038-1053	16
α-helix	1056-1062	7
α-helix	1077-1082	6
β-strand	1085-1090	6	118
β-strand	1094-1101	8	118
α-helix	1103-1116	14
α-helix	1144-1156	13
β-strand	1174-1178	5	118
β-strand	1185-1188	4	119
β-strand	1193-1198	6	119
β-strand	1216-1217	2	119
β-strand	1224-1231	8	119
α-helix	1234-1248	15
α-helix	1256-1270	15
α-helix	1282-1295	14
α-helix	1314-1317	4
α-helix	1334-1336	3
α-helix	1337-1339	3
β-strand	1341-1345	5	120
β-strand	1350-1354	5	120
α-helix	1368-1371	4
α-helix	1375-1398	24
α-helix	1405-1408	4
α-helix	1409-1411	3
α-helix	1427-1430	4
α-helix	1436-1441	6
α-helix	1442-1445	4
α-helix	1468-1477	10
α-helix	1480-1485	6
α-helix	1529-1537	9
α-helix	1539-1542	4
β-strand	1553-1554	2	121
β-strand	1561-1562	2	121
α-helix	1567-1576	10
α-helix	1581-1599	19
α-helix	1602-1604	3
β-strand	1606-1608	3	122
β-strand	1611	1	122
β-strand	1629-1638	10	122
β-strand	1642-1644	3	122
β-strand	1656-1662	7	122
β-strand	1665-1666	2	123
α-helix	1671-1673	3
α-helix	1676-1689	14
β-strand	1700-1701	2	122
β-strand	1704-1706	3	123
β-strand	1711-1713	3	123
β-strand	1715-1717	3	122
α-helix	1718-1719	2
α-helix	1723-1734	12
α-helix	1738-1751	14
β-strand	1779-1781	3	124
β-strand	1788-1791	4	125
β-strand	1799-1802	4	125
β-strand	1805-1810	6	124
β-strand	1816-1822	7	124
α-helix	1824-1826	3
α-helix	1833-1850	18
α-helix	1854-1856	3
β-strand	1861-1863	3	124
α-helix	1870-1875	6
β-strand	1884-1885	2	124
α-helix	1893-1897	5
α-helix	1900-1907	8
β-strand	1914-1918	5	124
α-helix	1921-1925	5
α-helix	1929-1945	17
α-helix	1947-1953	7
α-helix	1969-1970	2
α-helix	1973-1995	23
α-helix	2004-2010	7
α-helix	2072-2081	10
α-helix	2086-2088	3
β-strand	2090-2091	2	126
β-strand	2103-2107	5	126
α-helix	2108-2117	10
α-helix	2123-2124	2
β-strand	2125-2131	7	126
α-helix	2132-2133	2
β-strand	2139-2146	8	126
β-strand	2150	1	127
β-strand	2151-2152	2	128
β-strand	2157-2158	2	128
α-helix	2162-2164	3
β-strand	2173-2181	9	126
α-helix	2190-2202	13
β-strand	2212-2217	6	126
β-strand	2223-2228	6	126
α-helix	2232-2240	9
α-helix	2253-2255	3
β-strand	2258	1	126
β-strand	2260-2264	5	126
β-strand	2270-2271	2	126
β-strand	2273-2274	2	129
β-strand	2280	1	127
β-strand	2296-2297	2	129
α-helix	2300-2303	4
α-helix	2311-2314	4
α-helix	2321-2323	3

Chain A1: 7 helices, 9 β-strands

Element	Residues	Length	Sheet
α-helix	8-10	3
α-helix	13-15	3
α-helix	29-36	8
β-strand	41-45	5	76
α-helix	53-60	8
α-helix	61-63	3
β-strand	66-73	8	76
β-strand	80-88	9	76
α-helix	91-100	10
β-strand	105-106	2	77
β-strand	109-110	2	77
β-strand	112-115	4	76
β-strand	125	1	76
α-helix	135-138	4
β-strand	143	1	78
β-strand	148	1	78

Chain A2: 1 helix, 5 β-strands

Element	Residues	Length	Sheet
α-helix	14-18	5
β-strand	22-27	6	7
β-strand	32-40	9	7
β-strand	46-56	11	7
β-strand	64-76	13	7
β-strand	81-86	6	7

Chain A3: 3 helices, 5 β-strands

Element	Residues	Length	Sheet
α-helix	6-8	3
β-strand	12-17	6	7
β-strand	22-30	9	7
α-helix	35	1
β-strand	36-43	8	7
β-strand	54-62	9	7
α-helix	64-66	3
β-strand	67-72	6	7

46 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Nuclear cap-binding protein subunit 1	A5	protein	790	Homo sapiens	Q09161 (AlphaFold model)
U6 snRNA-associated Sm-like protein LSm7	A2	protein	103	Homo sapiens	Q9UK45 (AlphaFold model)
Splicing factor 3B subunit 6	z	protein	125	Homo sapiens	Q9Y3B4 (AlphaFold model)
Splicing factor 3A subunit 2	F	protein	464	Homo sapiens	Q15428 (AlphaFold model)
U5 small nuclear ribonucleoprotein 40 kDa protein	D	protein	357	Homo sapiens	Q96DI7
U2 small nuclear ribonucleoprotein A'	W	protein	255	Homo sapiens	P09661
U2 small nuclear ribonucleoprotein B''	B	protein	225	Homo sapiens	P08579
U5 small nuclear ribonucleoprotein 200 kDa helicase	s	protein	2136	Homo sapiens	O75643
Protein BUD31 homolog	Q	protein	144	Homo sapiens	P41223
Nuclear cap-binding protein subunit 2	A1	protein	156	Homo sapiens	P52298
U5 snRNA	5	RNA	116	Homo sapiens
Cell division cycle 5-like protein	L	protein	802	Homo sapiens	Q99459

39 more molecules are not listed.

Sequence of entity 1 (A5), FASTA

>7ABG_1 Nuclear cap-binding protein subunit 1 (chains A5)
MSRRRHSDENDGGQPHKRRKTSDANETEDHLESLICKVGEKSACSLESNLEGLAGVLEAD
LPNYKSKILRLLCTVARLLPEKLTIYTTLVGLLNARNYNFGGEFVEAMIRQLKESLKANN
YNEAVYLVRFLSDLVNCHVIAAPSMVAMFENFVSVTQEEDVPQVRRDWYVYAFLSSLPWV
GKELYEKKDAEMDRIFANTESYLKRRQKTHVPMLQVWTADKPHPQEEYLDCLWAQIQKLK
KDRWQERHILRPYLAFDSILCEALQHNLPPFTPPPHTEDSVYPMPRVIFRMFDYTDDPEG
PVMPGSHSVERFVIEENLHCIIKSHWKERKTCAAQLVSYPGKNKIPLNYHIVEVIFAELF
QLPAPPHIDVMYTTLLIELCKLQPGSLPQVLAQATEMLYMRLDTMNTTCVDRFINWFSHH
LSNFQFRWSWEDWSDCLSQDPESPKPKFVREVLEKCMRLSYHQRILDIVPPTFSALCPAN
PTCIYKYGDESSNSLPGHSVALCLAVAFKSKATNDEIFSILKDVPNPNQDDDDDEGFSFN
PLKIEVFVQTLLHLAAKSFSHSFSALAKFHEVFKTLAESDEGKLHVLRVMFEVWRNHPQM
IAVLVDKMIRTQIVDCAAVANWIFSSELSRDFTRLFVWEILHSTIRKMNKHVLKIQKELE
EAKEKLARQHKRRSDDDDRSSDRKDGVLEEQIERLQEKVESAQSEQKNLFLVIFQRFIMI
LTEHLVRCETDGTSVLTPWYKNCIERLQQIFLQHHQIIQQYMVTLENLLFTAELDPHILA
VFQQFCALQA

Sequence of entity 2 (A2), FASTA

>7ABG_2 U6 snRNA-associated Sm-like protein LSm7 (chains A2)
MADKEKKKKESILDLSKYIDKTIRVKFQGGREASGILKGFDPLLNLVLDGTIEYMRDPDD
QYKLTEDTRQLGLVVCRGTSVVLICPQDGMEAIPNPFIQQQDA

Sequence of entity 3 (z), FASTA

>7ABG_3 Splicing factor 3B subunit 6 (chains z)
MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTA
YVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGIN
TDPPK

Sequence of entity 4 (F), FASTA

>7ABG_4 Splicing factor 3A subunit 2 (chains F)
MDFQHRPGGKTGSGGVASSSESNRDRRERLRQLALETIDINKDPYFMKNHLGSYECKLCL
TLHNNEGSYLAHTQGKKHQTNLARRAAKEAKEAPAQPAPEKVKVEVKKFVKIGRPGYKVT
KQRDSEMGQQSLLFQIDYPEIAEGIMPRHRFMSAYEQRIEPPDRRWQYLLMAAEPYETIA
FKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNG
LPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG
VHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPP
APGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPG
VHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN

Sequence of entity 5 (D), FASTA

>7ABG_5 U5 small nuclear ribonucleoprotein 40 kDa protein (chains D)
MIEQQKRKGPELPLVPVKRQRHELLLGAGSGPGAGQQQATPGALLQAGPPRCSSLQAPIM
LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD
GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD
IRKKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTG
LSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKI
AAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ

Sequence of entity 6 (W), FASTA

>7ABG_6 U2 small nuclear ribonucleoprotein A' (chains W)
MVKLTAELIEQAAQYTNAVRDRELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGF
PLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSI
LRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKT
FNPGAGLPTDKKKGGPSPGDVEAIKNAIANASTLAEVERLKGLLQSGQIPGRERRSGPTD
DGEEEMEEDTVTNGS

Sequence of entity 7 (B), FASTA

>7ABG_7 U2 small nuclear ribonucleoprotein B'' (chains B)
MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELG
SSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTT
NKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEV
RLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK

Sequence of entity 8 (s), FASTA

>7ABG_8 U5 small nuclear ribonucleoprotein 200 kDa helicase (chains s)
MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK
PQMQEERRAKRRKRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFI
QAALGDQPRDILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKIT
DYGGDKEIQNMDDNIDETYGVNVQFESDEEEGDEDVYGEVREEASDDDMEGDEAVVRCTL
SANLVASGELMSSKKKDLHPRDIDAFWLQRQLSRFYDDAIVSQKKADEVLEILKTASDDR
ECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEKERIMGKMEADPELSKFL
YQLHETEKEDLIREERSRRERVRQSRMDTDLETMDLDQGGEALAPRQVLDLEDLVFTQGS
HFMANKRCQLPDGSFRRQRKGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKT
LNRIQSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIY
IAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG
GERTYTQLVRLIILDEIHLLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYED
VATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQ
VLVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPY
GFAIHHAGMTRVDRTLVEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGR
WTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDM
LNAEIVLGNVQNAKDAVNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTA
ALMLDKNNLVKYDKKTGNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSL
SSEFKNITVREEEKLELQKLLERVPIPVKESIEEPSAKINVLLQAFISQLKLEGFALMAD
MVYVTQSAGRLMRAIFEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVV
KKIEKKNFPFERLYDLNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKV
ELTITPDFQWDEKVHGSSEAFWILVEDVDSEVILHHEYFLLKAKYAQDEHLITFFVPVFE
PLPPQYFIRVVSDRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESL
YQDKFPFFNPIQTQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYIT
PMEALAEQVYMDWYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWK
QRKNVQNINLFVVDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDV
AHWLGCSATSTFNFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVI
VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYL
HEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYP
IYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEI
VTKTIENKQDAVDYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSK
CISIEDEMDVAPLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPI
RHHEDNLLRQLAQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSAELQSDTEEILSKAI
RLIQACVDVLSSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDKGVE
SVFDIMEMEDEERNALLQLTDSQIADVARFCNRYPNIELSYEVVDKDSIRSGGPVVVLVQ
LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKRLTLQQKAKVKLDFVAPATG
AHNYTLYFMSDAYMGCDQEYKFSVDVKEAETDSDSD

Sequence of entity 9 (Q), FASTA

>7ABG_9 Protein BUD31 homolog (chains Q)
MPKVKRSRKAPPDGWELIEPTLDELDQKMREAETEPHEGKRKVESLWPIFRIHHQKTRYI
FDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICR
VPKSKLEVGRIIECTHCGCRGCSG

Sequence of entity 10 (A1), FASTA

>7ABG_10 Nuclear cap-binding protein subunit 2 (chains A1)
MSGGLLKALRSDSYVELSQYRDQHFRGDNEEQEKLLKKSCTLYVGNLSFYTTEEQIYELF
SKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAMRYINGTRLDDRIIRTDWDAGFK
EGRQYGRGRSGGQVRDEYRQDYDAGRGGYGKLAQNQ

Sequence of entity 11 (5), FASTA

>7ABG_11 U5 snRNA (chains 5)
AUACUCUGGUUUCUCUUCAGAUCGCAUAAAUCUUUCGCCUUUUACUAAAGAUUUCCGUGG
AGAGGAACAACUCUGAGUCUUAACCCAAUUUUUUGAGCCUUGCCUUGGCAAGGCUA

Sequence of entity 12 (L), FASTA

>7ABG_12 Cell division cycle 5-like protein (chains L)
MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKK
TEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKAAQRDNEEETTDDP
RKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEAR
RLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFR
KLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAP
QISDAELQEVVKVGQASEIARQTAEESGITNSASSTLLSEYNVTNNSVALRTPRTPASQD
RILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGA
EGLTPRSGTTPKPVINSTPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGL
LGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEMKRMHKA
VQKDLPRPSEVNETILRPLNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKG
KTVGFGTNNSEHITYLEHNPYEKFSKEELKKAQDVLVQEMEVVKQGMSHGELSSEAYNQV
WEECYSQVLYLPGQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKIL
LGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQER
EKELQHRYADLLLEKETLKSKF

Ligands and cofactors

ID	Name	Formula	Copies
IHP	Inositol hexakisphosphate	C6 H18 O24 P6	1
GTP	Guanosine-5'-triphosphate	C10 H16 N5 O14 P3	1
MG	Magnesium ion	Mg	1
GTG	7-methyl-guanosine-5'-triphosphate-5'-guanosine	C21 H30 N10 O18 P3	1

Primary citation

Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Townsend, C., Leelaram, M.N., Agafonov, D.E. et al. Science (2020) 370. DOI 10.1126/science.abc3753 · PubMed

Other PDB entries of the same protein (UniProt Q09161 (AlphaFold model), which also has an AlphaFold model), best resolution first:

1H2V 2.0 Å, Structure of the human nuclear cap-binding-complex (CBC)
1H6K 2.0 Å, nuclear Cap Binding Complex
1H2T 2.1 Å, Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue…
1N52 2.11 Å, Cap Binding Complex
3FEY 2.2 Å, Crystal structure of the CBC-importin alpha complex.
1H2U 2.4 Å, Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue…
9HFL 2.62 Å, Cryo-EM structure of the human snRNA export complex comprising CBC-PHAX-CRM1-RanGTP and…
6D0Y 2.68 Å, X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding…
1N54 2.72 Å, Cap Binding Complex m7GpppG free
5OOB 2.79 Å, Complex of human nuclear cap-binding complex with M7GTP and nelf-E C-terminal peptide
5OO6 2.8 Å, Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide
8BY6 3.19 Å, Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and…

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