7F7X: Polyubiquitin-B

Protein complex between phosphorylated ubiquitin and Ubqln2 UBA. Determined by solution NMR. Released 18 May 2022.

Method: Solution NMR
Organism: Homo sapiens
Chains: 2
Atoms: 948
Mol. weight: 13.53 kDa
Released: 18 May 2022

Explore 7F7X in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7F7X contains 6 α-helices and 7 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 3 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	2-7	6	1
β-strand	11-16	6	1
β-strand	22	1	2
α-helix	23-34	12
α-helix	38-40	3
β-strand	41-45	5	1
β-strand	48-49	2	1
β-strand	55	1	2
α-helix	56-59	4
β-strand	68-71	4	1

Chain B: 3 helices, 0 β-strands

Element	Residues	Length
α-helix	579-591	13
α-helix	597-605	9
α-helix	612-618	7

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Polyubiquitin-B	A	protein	76	Homo sapiens	P0CG47 (AlphaFold model)
Ubiquilin-2	B	protein	45	Homo sapiens	Q9UHD9 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>7F7X_1 Polyubiquitin-B (chains A)
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYN
IQKESTLHLVLRLRGG

Sequence of entity 2 (B), FASTA

>7F7X_2 Ubiquilin-2 (chains B)
GPEVRFQQQLEQLNAMGFLNREANLQALIATGGDINAAIERLLGS

Primary citation

Kinetic Constraints in the Specific Interaction between Phosphorylated Ubiquitin and Proteasomal Shuttle Factors. Qin, L.Y., Gong, Z., Liu, K. et al. Biomolecules (2021) 11. DOI 10.3390/biom11071008 · PubMed

Other PDB entries of the same protein (UniProt P0CG47 (AlphaFold model), which also has an AlphaFold model), best resolution first:

5NVG 1.07 Å, Thr12 Phosphorylated Ubiquitin
5TOG 1.08 Å, Room temperature structure of ubiquitin variant u7ub25.2540
5TOF 1.12 Å, Room temperature structure of ubiquitin variant u7ub25
4XOF 1.15 Å, Observing the overall rocking motion of a protein in a crystal - Orthorhombic Ubiquitin…
5GOD 1.15 Å, Lys27-linked di-ubiquitin
5GOB 1.15 Å, Lys6-linked di-ubiquitin
5W46 1.18 Å, Structure of S65D Phosphomimetic Ubiquitin Refined at 1.2 Angstroms Resolution
7S6O 1.25 Å, The crystal structure of Lys48-linked di-ubiquitin
8IC9 1.25 Å, Lys48-linked K48C-diubiquitin
5DK8 1.32 Å, Human ubiquitin in the P1 space group
7CAP 1.33 Å, Cyclic Lys48-linked triubiquitin
5V1Y 1.42 Å, Crystal structure of the ternary RPN13 PRU-RPN2 (940-953)-ubiquitin complex

Browse structure collections

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