Q12306: Ubiquitin-like protein SMT3 (SMT3)

Ubiquitin-like protein SMT3 (SMT3) is a 101-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12306.

Gene
SMT3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
101 residues
Mean pLDDT
78.3
Model
AF-Q12306-F1 v6
Model created
1 Aug 2025
PDB structures
95

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Model confidence (pLDDT)

The mean pLDDT of this model is 78.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate40%
70 to 90Confident: backbone generally right33%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions16%

What pLDDT means and how to read it

Function

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer (PubMed:9312010). Sumoylation, the attachment of SUMO to target proteins, regulates multiple cellular events (By similarity)

Subunit structure

Activated by a E1 ligase composed of AOS1 and UBA2 (PubMed:9312010). Interacts with IRC20; the interaction is direct and occurs both covalently and non-covalently (PubMed:24155900)

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3UF8X-ray1.5 ÅA=13-98
6UKZX-ray1.52 ÅA/B=2-98
3UQAX-ray1.55 ÅA=13-98
3VAWX-ray1.55 ÅA=13-98
5YCAX-ray1.57 ÅA=20-93
7P7WX-ray1.57 ÅAAA/BBB=2-96
1EUVX-ray1.6 ÅB=13-98
6UKUX-ray1.68 ÅA=2-98
7P7IX-ray1.7 ÅAAA/BBB=2-96
6UKMX-ray1.74 ÅA=2-98
4G50X-ray1.75 ÅA/B=13-98
6P81X-ray1.75 ÅA=13-101
7P9LX-ray1.75 ÅAAA/BBB=2-96
6UL0X-ray1.76 ÅA=2-98
6UKVX-ray1.83 ÅA/B=2-98
6O49X-ray1.85 ÅA/B=13-98
9OIKX-ray1.86 ÅC/D=1-98
2EKEX-ray1.9 ÅC/D=13-98
3UQBX-ray1.9 ÅA=13-98
6UKXX-ray1.93 ÅA/B=2-98

Showing 20 of 95 experimental structures (best resolution first).

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