Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.5 Angstrom resolution. Determined by X-ray diffraction at 1.46 Å resolution. Released 6 Apr 2022.
Explore 7P8T in 3D Show helices and sheets RCSB PDB PDBe
7P8T contains 3 α-helices and 22 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| β-strand | 31-36 | 6 | 1 |
| β-strand | 39-50 | 12 | 1 |
| β-strand | 55-66 | 12 | 1 |
| β-strand | 71-83 | 13 | 1 |
| β-strand | 87-90 | 4 | 2 |
| β-strand | 99-114 | 16 | 2 |
| β-strand | 120-125 | 6 | 1 |
| β-strand | 130 | 1 | 2 |
| β-strand | 134-142 | 9 | 3 |
| β-strand | 146-150 | 5 | 3 |
| β-strand | 161-168 | 8 | 3 |
| β-strand | 172-179 | 8 | 2 |
| β-strand | 183-190 | 8 | 2 |
| β-strand | 192-195 | 4 | 4 |
| β-strand | 198-201 | 4 | 4 |
| β-strand | 209 | 1 | 5 |
| α-helix | 218-222 | 5 | |
| β-strand | 223 | 1 | 5 |
| α-helix | 226-228 | 3 | |
| α-helix | 231-234 | 4 | |
| β-strand | 236-237 | 2 | 1 |
| β-strand | 241-248 | 8 | 1 |
| β-strand | 254-273 | 20 | 2 |
| β-strand | 277-299 | 23 | 2 |
| β-strand | 304-310 | 7 | 2 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Leucotoxin LukEv | A | protein | 308 | Staphylococcus aureus | Q2FXB0 (AlphaFold model) |
>7P8T_1 Leucotoxin LukEv (chains A) MSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQFDFVKDKKYN KDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVSLINYLPKNKI ETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQNSKSVKWGVKA NEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPSFITTLSHEKG SSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNWKTHEIKVKGH NKHHHHHH
Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins. Lambey, P., Otun, O., Cong, X. et al. Elife (2022) 11. DOI 10.7554/eLife.72555 · PubMed
Other PDB entries of the same protein (UniProt Q2FXB0 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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