7PGZ: Dark-adapted AsLOV2 Q513L

Structure of dark-adapted AsLOV2 Q513L. Determined by X-ray diffraction at 0.9 Å resolution. Released 11 May 2022.

Method: X-ray diffraction
Resolution: 0.9 Å
Organism: Avena sativa
Chains: 1
Atoms: 2,184
Mol. weight: 18.66 kDa
Ligands: FMN, MG
Released: 11 May 2022

Explore 7PGZ in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7PGZ contains 7 α-helices and 5 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain AAA: 7 helices, 5 β-strands

Element	Residues	Length	Sheet
α-helix	404-406	3
α-helix	408-410	3
β-strand	414-418	5	1
β-strand	427-430	4	1
α-helix	432-438	7
α-helix	442-445	4
α-helix	450-453	4
α-helix	460-471	12
β-strand	476-483	8	1
β-strand	489-500	12	1
β-strand	506-516	11	1
α-helix	522-543	22

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
NPH1-1	AAA	protein	146	Avena sativa	O49003 (AlphaFold model)

Sequence of entity 1 (AAA), FASTA

>7PGZ_1 NPH1-1 (chains AAA)
GEFLATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNCRFLQGPETDR
ATVRKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVLLDGTEHV
RDAAEREGVMLIKKTAENIDEAAKEL

Ligands and cofactors

ID	Name	Formula	Copies
FMN	Flavin mononucleotide	C17 H21 N4 O9 P	1
MG	Magnesium ion	Mg	2

Water and common crystallization additives (EDO, GOL) are not listed.

Primary citation

Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine. Dietler, J., Gelfert, R., Kaiser, J. et al. Nat Commun (2022) 13:2618-2618. DOI 10.1038/s41467-022-30252-4 · PubMed

Other PDB entries of the same protein (UniProt O49003 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7PH0 0.98 Å, Structure of light-adapted AsLOV2 Q513L
7PGX 1.0 Å, Structure of dark-adapted AsLOV2 wild type
7PGY 1.09 Å, Structure of light-adapted AsLOV2 wild type
2V0U 1.4 Å, n- and c-terminal helices of oat lov2 (404-546) are involved in light-induced signal…
2V1B 1.55 Å, N- and C-terminal helices of oat LOV2 (404-546) are involved in light-induced signal…
2WKQ 1.6 Å, Structure of a photoactivatable Rac1 containing the Lov2 C450A Mutant
2V1A 1.65 Å, N- and C-terminal helices of oat LOV2 (404-546) are involved in light-induced signal…
2V0W 1.7 Å, N- and C-terminal helices of oat LOV2 (404-546) are involved in light- induced signal…
6NTP 1.89 Å, PTP1B Domain of PTP1B-LOV2 Chimera
2WKP 1.9 Å, Structure of a photoactivatable Rac1 containing Lov2 Wildtype
4WF0 1.95 Å, Crystal Structure of iLID - an Improved Light-Inducible Dimer
5EFW 2.1 Å, Crystal structure of LOV2-Zdk1 - the complex of oat LOV2 and the affibody protein Zdark1

Browse structure collections

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