7TTN: The beta-tubulin folding intermediate II

The beta-tubulin folding intermediate II. Determined by electron microscopy at 3.3 Å resolution. Released 28 Dec 2022.

Method: Electron microscopy
Resolution: 3.3 Å
Organism: Homo sapiens
Chains: 9
Atoms: 34,563
Mol. weight: 528.65 kDa
Ligands: AF3, MG, ADP
Released: 28 Dec 2022

Explore 7TTN in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7TTN contains 204 α-helices and 216 β-strands across 9 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 12 helices, 13 β-strands

Element	Residues	Length	Sheet
β-strand	3-9	7	1
α-helix	10-27	18
β-strand	30	1	2
β-strand	36	1	2
β-strand	52-53	2	3
β-strand	59-60	2	3
β-strand	63-67	5	1
α-helix	70-72	3
α-helix	74-78	5
α-helix	87-89	3
β-strand	90-92	3	1
α-helix	103-107	5
α-helix	109-112	4
α-helix	114-126	13
β-strand	130-136	7	1
α-helix	142-158	17
β-strand	163-166	4	1
β-strand	169	1	4
α-helix	181-193	13
β-strand	198-200	3	1
β-strand	202	1	4
β-strand	265-266	2	1
α-helix	375-390	16
α-helix	396-399	4
α-helix	405-421	17

Chain B: 27 helices, 24 β-strands

Element	Residues	Length	Sheet
α-helix	7-8	2
α-helix	11-13	3
β-strand	15	1	5
α-helix	16	1
β-strand	20-23	4	6
α-helix	25-29	5
α-helix	30-43	14
β-strand	53-57	5	7
β-strand	63-66	4	7
α-helix	69-75	7
α-helix	81-96	16
α-helix	101-120	20
α-helix	125-142	18
α-helix	143-146	4
α-helix	160-162	3
α-helix	165-169	5
α-helix	176-187	12
α-helix	199-201	3
β-strand	202-208	7	8
α-helix	212-214	3
β-strand	216-218	3	8
β-strand	222-223	2	9
β-strand	233-234	2	9
β-strand	238-241	4	10
β-strand	242	1	11
β-strand	256-257	2	12
β-strand	259	1	13
α-helix	262-284	23
β-strand	290-293	4	10
α-helix	296-298	3
α-helix	299-307	9
β-strand	311-314	4	10
α-helix	319-328	10
β-strand	333	1	11
β-strand	345-346	2	10
β-strand	349-354	6	9
β-strand	359-364	6	9
β-strand	373-379	7	8
α-helix	382-404	23
β-strand	408-410	3	14
α-helix	414-428	15
α-helix	435-443	9
α-helix	444-446	3
α-helix	447-456	10
α-helix	460-473	14
β-strand	478	1	15
β-strand	491	1	15
α-helix	492-495	4
β-strand	498-500	3	14
α-helix	501-520	20
β-strand	521-526	6	6

Chain C: 22 helices, 24 β-strands

Element	Residues	Length	Sheet
β-strand	14-17	4	7
α-helix	19-26	8
α-helix	29-35	7
β-strand	46-50	5	16
β-strand	56-59	4	16
α-helix	62-67	6
β-strand	71	1	17
α-helix	77-89	13
α-helix	96-106	11
α-helix	109-113	5
α-helix	118-138	21
β-strand	141	1	18
α-helix	150-163	14
α-helix	172-183	12
β-strand	195-201	7	19
α-helix	205-207	3
β-strand	209-211	3	19
β-strand	215-217	3	20
α-helix	225-227	3
β-strand	231-232	2	20
β-strand	237-240	4	21
β-strand	244	1	22
β-strand	255-257	3	13
α-helix	260-283	24
β-strand	288-291	4	21
β-strand	295	1	22
α-helix	297-304	8
β-strand	309-310	2	21
α-helix	316-326	11
β-strand	331	1	21
α-helix	339-341	3
β-strand	348-352	5	20
β-strand	357-360	4	20
β-strand	370-376	7	19
α-helix	379-401	23
β-strand	405-407	3	18
α-helix	411-424	14
α-helix	429-431	3
α-helix	432-439	8
α-helix	444-453	10
α-helix	457-470	14
β-strand	485-488	4	23
β-strand	493-496	4	23
β-strand	503-505	3	18
α-helix	507-525	19
β-strand	526-531	6	7

Chain D: 22 helices, 27 β-strands

Element	Residues	Length	Sheet
β-strand	19	1	17
α-helix	22-24	3
β-strand	25-28	4	16
α-helix	30-47	18
β-strand	58-62	5	24
β-strand	68-71	4	24
α-helix	74-80	7
β-strand	83	1	25
α-helix	86-99	14
α-helix	109-125	17
α-helix	130-148	19
β-strand	153	1	26
α-helix	164-172	9
α-helix	185-191	7
α-helix	206-208	3
β-strand	209-213	5	27
α-helix	219-221	3
β-strand	223-225	3	27
β-strand	228-230	3	28
β-strand	234	1	29
β-strand	243	1	28
β-strand	246	1	30
β-strand	248-250	3	29
β-strand	251	1	31
α-helix	257-258	2
β-strand	264-268	5	13
α-helix	271-294	24
β-strand	299-301	3	29
α-helix	308-316	9
β-strand	321-322	2	29
α-helix	327-337	11
β-strand	342	1	31
β-strand	356	1	30
β-strand	358-363	6	28
β-strand	370-375	6	28
β-strand	383-387	5	27
α-helix	392-414	23
β-strand	418-419	2	26
α-helix	424-436	13
α-helix	437-439	3
α-helix	445-454	10
α-helix	457-466	10
α-helix	470-483	14
β-strand	489	1	32
β-strand	500	1	32
α-helix	501-504	4
β-strand	508-509	2	26
α-helix	510-529	20
β-strand	530-536	7	16

Chain E: 23 helices, 25 β-strands

Element	Residues	Length	Sheet
β-strand	12	1	25
β-strand	17-19	3	24
α-helix	21-39	19
α-helix	40-42	3
β-strand	49-54	6	33
β-strand	61-64	4	33
α-helix	69-73	5
α-helix	81-94	14
α-helix	99-117	19
α-helix	123-142	20
β-strand	146-147	2	34
α-helix	152-166	15
α-helix	171-173	3
α-helix	176-188	13
α-helix	196-198	3
β-strand	199-206	8	35
α-helix	209-211	3
β-strand	213-214	2	35
β-strand	218-220	3	36
β-strand	224	1	37
β-strand	232-233	2	36
β-strand	237-240	4	37
β-strand	244	1	38
β-strand	254-256	3	13
α-helix	261-283	23
β-strand	289-292	4	37
β-strand	296	1	38
α-helix	298-306	9
β-strand	310-312	3	37
α-helix	317-320	4
α-helix	323-326	4
β-strand	331-332	2	37
β-strand	346-354	9	36
β-strand	357-365	9	36
β-strand	371-377	7	35
α-helix	380-402	23
β-strand	405-408	4	34
α-helix	412-425	14
α-helix	432-443	12
α-helix	446-453	8
α-helix	458-469	12
β-strand	476-478	3	39
β-strand	485-487	3	39
α-helix	488-491	4
β-strand	494-496	3	34
α-helix	497-515	19
β-strand	517-522	6	24
α-helix	524-529	6

Chain F: 22 helices, 24 β-strands

Element	Residues	Length	Sheet
α-helix	29-47	19
β-strand	58-62	5	40
β-strand	68-71	4	40
α-helix	74-80	7
α-helix	86-101	16
α-helix	106-125	20
α-helix	130-149	20
β-strand	153-154	2	41
α-helix	160-169	10
α-helix	177-179	3
α-helix	180-192	13
α-helix	205-207	3
β-strand	208-215	8	42
α-helix	218-220	3
β-strand	222-224	3	42
β-strand	227-229	3	43
β-strand	240-242	3	43
β-strand	245-249	5	44
β-strand	253	1	45
β-strand	262	1	13
β-strand	264-266	3	46
α-helix	270-293	24
β-strand	297-301	5	44
α-helix	302	1
β-strand	309	1	45
α-helix	311-318	8
β-strand	323-328	6	44
α-helix	333-340	8
β-strand	344-345	2	44
α-helix	348-350	3
β-strand	357-358	2	44
β-strand	359-366	8	43
β-strand	372-379	8	43
β-strand	386-392	7	42
α-helix	395-417	23
β-strand	420-423	4	41
α-helix	427-442	16
α-helix	447-457	11
α-helix	460-468	9
α-helix	473-483	11
β-strand	491-493	3	47
β-strand	500-502	3	47
α-helix	503-506	4
β-strand	509-511	3	41
α-helix	512-529	18
β-strand	532-538	7	33

Chain G: 27 helices, 25 β-strands

Element	Residues	Length	Sheet
β-strand	9-13	5	40
α-helix	15-18	4
α-helix	23-31	9
α-helix	32-34	3
β-strand	42-46	5	48
β-strand	52-55	4	48
α-helix	58-64	7
α-helix	70-85	16
α-helix	92-109	18
α-helix	114-134	21
β-strand	137	1	49
α-helix	139-141	3
α-helix	149-154	6
α-helix	165-176	12
α-helix	177-179	3
β-strand	181	1	50
β-strand	189	1	50
β-strand	196-199	4	51
α-helix	205-207	3
β-strand	209-211	3	51
β-strand	213-216	4	52
β-strand	228-229	2	52
β-strand	234-237	4	53
β-strand	241	1	54
β-strand	250-254	5	46
α-helix	257-259	3
α-helix	261-265	5
α-helix	270-279	10
β-strand	285-288	4	53
β-strand	292	1	54
α-helix	299-302	4
β-strand	306-308	3	53
α-helix	313-323	11
β-strand	328	1	53
β-strand	332	1	55
β-strand	338	1	55
β-strand	350-355	6	52
β-strand	360-365	6	52
β-strand	374-377	4	51
α-helix	382-404	23
β-strand	408-410	3	49
α-helix	414-426	13
α-helix	427-429	3
α-helix	434-445	12
α-helix	447-455	9
α-helix	462-475	14
α-helix	482-484	3
α-helix	498-501	4
β-strand	504-506	3	49
α-helix	507-525	19
β-strand	527-533	7	40
α-helix	534-535	2

Chain H: 25 helices, 27 β-strands

Element	Residues	Length	Sheet
β-strand	15-18	4	48
α-helix	20-37	18
β-strand	47-49	3	56
β-strand	59-60	2	56
α-helix	64-67	4
α-helix	75-90	16
α-helix	97-107	11
α-helix	110-113	4
α-helix	119-137	19
β-strand	142-143	2	57
α-helix	149-160	12
α-helix	166-168	3
α-helix	169-183	15
β-strand	185	1	58
β-strand	193	1	58
α-helix	196-198	3
β-strand	199-206	8	59
α-helix	209-211	3
β-strand	213-214	2	59
β-strand	218-220	3	60
β-strand	232-233	2	60
β-strand	238-241	4	61
β-strand	245	1	62
β-strand	254-256	3	46
β-strand	258	1	63
α-helix	263-283	21
β-strand	289-292	4	61
β-strand	296	1	62
α-helix	298-305	8
β-strand	310-312	3	61
α-helix	319-323	5
α-helix	324-328	5
β-strand	332	1	61
β-strand	344	1	61
β-strand	350-354	5	60
β-strand	359-363	5	60
β-strand	372-378	7	59
α-helix	381-403	23
β-strand	406-409	4	57
α-helix	413-423	11
α-helix	426-428	3
α-helix	435-442	8
α-helix	443-446	4
α-helix	447-453	7
α-helix	462-467	6
α-helix	469-471	3
β-strand	478-480	3	64
β-strand	487-489	3	64
α-helix	490-493	4
β-strand	496-498	3	57
α-helix	499-516	18
β-strand	519-524	6	48

1 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Tubulin beta chain	A	protein	444	Homo sapiens	P07437 (AlphaFold model)
T-complex protein 1 subunit theta	B	protein	547	Homo sapiens	P50990 (AlphaFold model)
T-complex protein 1 subunit eta	C	protein	553	Homo sapiens	Q99832 (AlphaFold model)
T-complex protein 1 subunit epsilon	D	protein	541	Homo sapiens	P48643 (AlphaFold model)
T-complex protein 1 subunit beta	E	protein	535	Homo sapiens	P78371
T-complex protein 1 subunit delta	F	protein	539	Homo sapiens	P50991
T-complex protein 1 subunit alpha	G	protein	556	Homo sapiens	P17987
T-complex protein 1 subunit gamma	H	protein	545	Homo sapiens	P49368
T-complex protein 1 subunit zeta	I	protein	531	Homo sapiens	P40227

Sequence of entity 1 (A), FASTA

>7TTN_1 Tubulin beta chain (chains A)
MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM
AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATAEEEEDFGEEAEEEA

Sequence of entity 2 (B), FASTA

>7TTN_2 T-complex protein 1 subunit theta (chains B)
MALHVPKAPGFAQMLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHL
EKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLR
IGLSVSEVIEGYEIACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLA
KLIAQACVSIFPDSGHFNVDNIRVCKILGSGISSSSVLHGMVFKKETEGDVTSVKDAKIA
VYSCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADM
ALHYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGHCDSVYLSEVGDTQV
VVFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELA
KQITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGL
DIEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKK
DWDDDQN

Sequence of entity 3 (C), FASTA

>7TTN_3 T-complex protein 1 subunit eta (chains C)
MMPTPVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISN
DGATILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQI
IIRAFRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVV
DAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALL
NVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVAT
QYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGRCQVFEETQIGGERYNF
FTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYL
RDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGSHHHHHHG
SGTWYGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAP
TAAGRGRGRGRPH

Sequence of entity 4 (D), FASTA

>7TTN_4 T-complex protein 1 subunit epsilon (chains D)
MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKM
MVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEA
EQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNS
CHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMP
KKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLA
ICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQ
EISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVY
GGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRAR
QVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESE
E

Sequence of entity 5 (E), FASTA

>7TTN_5 T-complex protein 1 subunit beta (chains E)
MASLSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS
LMVTNDGATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKK
IHPQTIIAGWREATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFT
KLAVEAVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIA
NTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYP
EQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLI
HFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHA
VTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDM
REGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC

Sequence of entity 6 (F), FASTA

>7TTN_6 T-complex protein 1 subunit delta (chains F)
MPENVAPRSGATAGAAGGRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKM
IQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSC
TKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELSDRETLLNSATTSLNSKVVSQYS
SLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVSNSGITR
VEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLI
QKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAE
LAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRA
LIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTEL
RNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVVNTR

Sequence of entity 7 (G), FASTA

>7TTN_7 T-complex protein 1 subunit alpha (chains G)
MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGAT
ILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISG
YRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIK
YTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFS
LQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYF
VEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDE
LILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALS
IYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPER
KNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD
KHGSYEDAVHSGALND

Sequence of entity 8 (H), FASTA

>7TTN_8 T-complex protein 1 subunit gamma (chains H)
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
DAGQE

Sequence of entity 9 (I), FASTA

>7TTN_9 T-complex protein 1 subunit zeta (chains I)
MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSFLKG

Ligands and cofactors

ID	Name	Formula	Copies
AF3	Aluminum fluoride	Al F3	8
MG	Magnesium ion	Mg	8
ADP	Adenosine-5'-diphosphate	C10 H15 N5 O10 P2	8

Primary citation

Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Gestaut, D., Zhao, Y., Park, J. et al. Cell (2022) 185:4770-4787.e20. DOI 10.1016/j.cell.2022.11.014 · PubMed

Other PDB entries of the same protein (UniProt P07437 (AlphaFold model), which also has an AlphaFold model), best resolution first:

3QNZ 2.2 Å, Orthorhombic form of IgG1 Fab fragment (in complex with antigenic tubulin peptide)…
3QO0 2.3 Å, Monoclinic form of IgG1 Fab fragment (in complex with antigenic peptide) sharing same Fv…
8BPO 2.8 Å, Structure of rabbit 80S ribosome translating beta-tubulin in complex with…
7TTT 2.9 Å, The beta-tubulin folding intermediate III
8V2J 2.9 Å, Structure of alpha1B and betaI/IVb microtubule bound to GDP
9COC 2.9 Å, Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GDP
7TRG 3.0 Å, The beta-tubulin folding intermediate I
7X0S 3.1 Å, Human TRiC-tubulin-S3
9BP6 3.1 Å, Structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
9CMM 3.1 Å, Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GMPCPP
9HQ4 3.28 Å, TTLL11 bound to microtubule
6I2I 3.6 Å, Refined 13pf Hela Cell Tubulin microtubule (EML4-NTD decorated)

Browse structure collections

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