7UCJ: 60S ribosomal protein L8
Mammalian 80S translation initiation complex with mRNA and Harringtonine. Determined by electron microscopy at 3.1 Å resolution. Released 1 Jun 2022.
- Method
- Electron microscopy
- Resolution
- 3.1 Å
- Organism
- Oryctolagus cuniculus
- Chains
- 79
- Atoms
- 208,732
- Mol. weight
- 3094.04 kDa
- Ligands
- ZN, MQ6, MG
- Released
- 1 Jun 2022
Explore 7UCJ in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7UCJ contains 517 α-helices and 520 β-strands across 73 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 7 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 42-48 | 7 | |
| β-strand | 72-74 | 3 | 43 |
| α-helix | 75-78 | 4 | |
| α-helix | 79-81 | 3 | |
| α-helix | 84-92 | 9 | |
| β-strand | 98 | 1 | 116 |
| β-strand | 100-102 | 3 | 44 |
| α-helix | 103-106 | 4 | |
| β-strand | 110-112 | 3 | 43 |
| β-strand | 122-126 | 5 | 44 |
| β-strand | 128-129 | 2 | 43 |
| α-helix | 131-140 | 10 | |
| β-strand | 142-146 | 5 | 44 |
Chain A: 9 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-9 | 4 | |
| α-helix | 29-32 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 47 |
| β-strand | 58-63 | 6 | 47 |
| β-strand | 72-77 | 6 | 47 |
| α-helix | 78 | 1 | |
| β-strand | 79 | 1 | 48 |
| β-strand | 83 | 1 | 49 |
| β-strand | 87-91 | 5 | 47 |
| β-strand | 101 | 1 | 47 |
| α-helix | 108 | 1 | |
| β-strand | 112-116 | 5 | 47 |
| β-strand | 126 | 1 | 47 |
| β-strand | 134-140 | 7 | 47 |
| β-strand | 145-149 | 5 | 47 |
| β-strand | 155-159 | 5 | 47 |
| β-strand | 164-166 | 3 | 47 |
| β-strand | 169 | 1 | 48 |
| α-helix | 174-176 | 3 | |
| α-helix | 178-179 | 2 | |
| α-helix | 182-190 | 9 | |
| α-helix | 198-200 | 3 | |
| β-strand | 224-225 | 2 | 50 |
| β-strand | 237-238 | 2 | 50 |
Chain Aa: 5 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 20-22 | 3 | 142 |
| β-strand | 29-31 | 3 | 142 |
| β-strand | 36-43 | 8 | 143 |
| α-helix | 50-56 | 7 | |
| β-strand | 57 | 1 | 70 |
| α-helix | 62-65 | 4 | |
| β-strand | 66-73 | 8 | 143 |
| α-helix | 75-80 | 6 | |
| α-helix | 96-97 | 2 | |
| α-helix | 99 | 1 | |
Chain AA: 9 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-21 | 10 | |
| β-strand | 25 | 1 | 145 |
| α-helix | 32-34 | 3 | |
| β-strand | 38-41 | 4 | 145 |
| β-strand | 47-49 | 3 | 145 |
| α-helix | 51-66 | 16 | |
| α-helix | 71-73 | 3 | |
| β-strand | 74-78 | 5 | 146 |
| α-helix | 81-94 | 14 | |
| β-strand | 97-100 | 4 | 146 |
| β-strand | 121-124 | 4 | 146 |
| α-helix | 131-136 | 6 | |
| β-strand | 144-148 | 5 | 146 |
| β-strand | 159-162 | 4 | 146 |
| α-helix | 168-186 | 19 | |
| α-helix | 199-201 | 3 | |
| α-helix | 207-216 | 10 | |
Chain b: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-19 | 8 | |
| α-helix | 22-25 | 4 | |
| α-helix | 37-49 | 13 | |
| α-helix | 50-53 | 4 | |
| α-helix | 54-75 | 22 | |
| α-helix | 91-100 | 10 | |
| α-helix | 106-116 | 11 | |
Chain B: 17 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-10 | 2 | |
| α-helix | 14-16 | 3 | |
| α-helix | 32-35 | 4 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 52 |
| β-strand | 45-54 | 10 | 53 |
| β-strand | 56-59 | 4 | 54 |
| β-strand | 71-73 | 3 | 54 |
| β-strand | 76-80 | 5 | 53 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 52 |
| β-strand | 98-106 | 9 | 52 |
| α-helix | 112-115 | 4 | |
| α-helix | 116-118 | 3 | |
| α-helix | 135-138 | 4 | |
| α-helix | 140-156 | 17 | |
| β-strand | 159-165 | 7 | 52 |
| α-helix | 168-170 | 3 | |
| α-helix | 177-179 | 3 | |
| β-strand | 180-186 | 7 | 52 |
| α-helix | 190-199 | 10 | |
| β-strand | 204-205 | 2 | 52 |
| β-strand | 216-222 | 7 | 53 |
| α-helix | 223-224 | 2 | |
| β-strand | 225-229 | 5 | 55 |
| α-helix | 231-234 | 4 | |
| α-helix | 237-241 | 5 | |
| β-strand | 270-273 | 4 | 55 |
| β-strand | 276-288 | 13 | 53 |
| β-strand | 292-294 | 3 | 56 |
| β-strand | 297-299 | 3 | 56 |
| β-strand | 320 | 1 | 57 |
| β-strand | 324 | 1 | 57 |
| β-strand | 330-334 | 5 | 53 |
| β-strand | 344-349 | 6 | 53 |
| α-helix | 357-360 | 4 | |
| β-strand | 365-368 | 4 | 54 |
| α-helix | 382-389 | 8 | |
Chain Bb: 3 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-16 | 5 | |
| β-strand | 32-36 | 5 | 147 |
| β-strand | 43-47 | 5 | 147 |
| β-strand | 55 | 1 | 148 |
| β-strand | 62 | 1 | 148 |
| β-strand | 64-65 | 2 | 149 |
| α-helix | 71 | 1 | |
| β-strand | 72-73 | 2 | 149 |
| α-helix | 74 | 1 | |
| β-strand | 78-81 | 4 | 147 |
Chain BB: 10 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 24-27 | 4 | |
| β-strand | 28-34 | 7 | 152 |
| β-strand | 43-50 | 8 | 152 |
| α-helix | 51-52 | 2 | |
| β-strand | 53 | 1 | 153 |
| β-strand | 56 | 1 | 153 |
| α-helix | 58-61 | 4 | |
| β-strand | 66-70 | 5 | 152 |
| α-helix | 71-74 | 4 | |
| β-strand | 82-91 | 10 | 152 |
| β-strand | 95-105 | 11 | 152 |
| α-helix | 107-113 | 7 | |
| β-strand | 120-128 | 9 | 152 |
| β-strand | 134-142 | 9 | 152 |
| β-strand | 143 | 1 | 154 |
| α-helix | 158-172 | 15 | |
| α-helix | 181-188 | 8 | |
| α-helix | 192-201 | 10 | |
| β-strand | 207 | 1 | 154 |
| β-strand | 211-219 | 9 | 152 |
| α-helix | 220-223 | 4 | |
| α-helix | 225-231 | 7 | |
65 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| P-site tRNA | 2 | RNA | 76 | Oryctolagus cuniculus | |
| mRNA | 1 | RNA | 6 | Oryctolagus cuniculus | |
| 28s rRNA | 5 | RNA | 3499 | Oryctolagus cuniculus | |
| 5S rRNA | 7 | RNA | 120 | Oryctolagus cuniculus | |
| 5.8S rRNA | 8 | RNA | 156 | Oryctolagus cuniculus | |
| 18S rRNA | 9 | RNA | 1698 | Oryctolagus cuniculus | |
| 60S ribosomal protein L8 | A | protein | 248 | Oryctolagus cuniculus | G1TT27 (AlphaFold model) |
| 60S ribosomal protein L3 | B | protein | 394 | Oryctolagus cuniculus | G1TL06 (AlphaFold model) |
| 60S ribosomal protein L4 | C | protein | 360 | Oryctolagus cuniculus | A0A5F9DCT1 (AlphaFold model) |
| Ribosomal_L18_c domain-containing protein | D | protein | 291 | Oryctolagus cuniculus | P19949 (AlphaFold model) |
| 60S ribosomal protein L6 | E | protein | 250 | Oryctolagus cuniculus | G1SKF7 |
| 60S ribosomal protein L7 | F | protein | 225 | Oryctolagus cuniculus | G1SV32 |
67 more molecules are not listed.
Sequence of entity 1 (2), FASTA
>7UCJ_1 P-site tRNA (chains 2)
GAGCAGAGUGGCGCAGCGGAAGCGUGCUGGGCCCAUAACCCAGAGGUCGAUGGAUCGAAA
CCAUCCUCUGCUACCA
Sequence of entity 2 (1), FASTA
>7UCJ_2 mRNA (chains 1)
AGCAUG
Sequence of entity 3 (5), FASTA
>7UCJ_3 28s rRNA (chains 5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGCGGGGCGCGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCGGUAGCG
GCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCAGCCCAA
AGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAACAAGUA
CCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAACCGUUA
AGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGCCGGUCC
GGCCGUGCCGGCGGGGCGGAUCUCCCGCUCCCGUCGGCGGGGGACCGCCCCCCGGCCGGC
GACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACG
GCUGGGAAGGCCCCGGCGGGGAAGGUGGCCCGGGGGCCCCGGGUGUUACAGCCCCGCCCC
GGCAGCAGCAGCUCGCCGAAUCCCGGGGCCGAGGGAGCGAGACCCGUGCCGCCGCGCUCU
CCCCCCUGGGGGGGCCGGGCCACCCCUCCCACGGCGCGACCGCUGGGGCGGACUGUCCAG
UGCGCCCCGGGCGGGUCGCGCCGUCGGGCCCGGGGGCCACGGCGUCCCCCGCGAGCGCAC
GGGGUCGGCGGCGAUGUCGGCUACCCACCCGACCCGUCUUGAAACACGGACCAAGGAGUC
UAACACGUGCGCGAGUCGGGGGCUACGAAAGCCGCCGUGGCGCAAUGAAGGUGAAGGCCG
GCGGCGCCGCCGGCCGAGGUGGGAUCCCGAGGCCUUCCAGUCCGCCGAGGGCGCACCACC
GGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGAA
AGAUGGUGAACUAUGCCUGGGCAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUAG
CGGUCCUGACGUGCGAAUCGGUCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAAC
CAUCUAGUAGCUGGUUCCCUCCAAAGUUUCCCUCAGGAUAGCUGGCGCUCUCCGCAGUUU
UAUCCGGUAAAGCGAAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAA
ACUUUAAAUGGGUAAGAAGCCCGGCUCGCUGGUGUGGAGCCGGGCGUGGAAUGCGAGUGC
CUAGUGGGCCACUUUUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUA
AGGCGCCCGAUGCCGACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCA
GGACCUGCCGAAUCAACUAGCCCUGAAAAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCC
GGCCGUCGCUGGCAGUCGGCAGAGCGAGAAAGAGAGUGGCGCGGACGCUACGCCGCGACG
AGUAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCC
GCAGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGU
GGAGAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGC
GAGCGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGCCCUCAGCCGAUCGAAAGGGAG
UCGGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCG
GUAACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUG
UGAAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAG
CGUCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAG
GGUGUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCC
UCUGGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGG
AUAAGGAUUGGCUCUAAGGGCUGGCAGCCGACUUAGAACUGGUGCGGACCAGGGGAAUCC
GACUGUUUAAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAUGUGAU
UUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAACGGCG
GGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCA
UGAAUGGAUGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAGCCAAG
GGAACGGGCUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCUG
GCACGGUGAAGAGACAUGAUCGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCGG
GCUCUCGCUUCUGGCGCCAAGCGCCCGGCCGGCCGGGCGCGACCCGCUCCGGGGACAGUG
CCAGGUGGGGAGUUUGACUGGGGCGGUACACCUGUCAAACGGUAACGCAGGUGUCCUAAG
GCGAGCUCAGGGAGGACAGAAACCUCCCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCU
UGAUUUUCAGUACGAAUACAGACCGUGAAAGCGGGGCCUCACGAUCCUUCUGACCUUUUG
GGUUUUAAGCAGGAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAA
GCGUUCAUAGCGACGUCGCUUUUUGAUCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAG
CAGAAUUCACCAAGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGA
CCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUG
CUCAGUACGAGAGGAACCGCAGGUUCAGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCA
AUGGGGCGAAGCUACCAUCUGUGGGAUUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCC
CAGGCGGAACGAUAGCGCCGGAGCCUCGGUUGGCCUCGGAUAGCCGGUCCCCCGCCGGGG
UCCGGUGCGGAGAGCCCUUCGUCCCGGGAAACGGGGCGGCCGGAAAGGGGGCCGCCCUCU
CGCCCGUCACGCACCGCACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACGACCU
GCUUCUGGGUCGGGGUUUCGUACGUAGCAGAGCAGCUGCUGCGAUCUAUUGAAAGUCAGC
CCUCGACACAAGGGUUUGU
Sequence of entity 4 (7), FASTA
>7UCJ_4 5S rRNA (chains 7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 5 (8), FASTA
>7UCJ_5 5.8S rRNA (chains 8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGNNNNNUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCU
Sequence of entity 6 (9), FASTA
>7UCJ_6 18S rRNA (chains 9)
UACCUGGUUGAUCCUGCCAGUAGCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCUA
AGUACGCACGGCCGGUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUGGUUCCUU
UGGUCGCUCGUACUUGGAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCCGACGGGCGCU
GACCCCCUUCGCGGGGGGGAUGCGUGCAUUUAUCAGUGGUGACUCUAGAUAACCUCGGGC
CGAUCGCACGCCCGGCGGCGACGACCCAUUCGAACGUCUGCCCUAUCAACUUUCGAUGGU
AGUCGCCGUGCCUACCAUGGUGACCACGGGUGACGGGGAAUCAGGGUUCGAUUCCGGAGA
GGGAGCCUGAGAAACGGCUACCACAUCCAAGGAAGGCAGCAGGCGCGCAAAUUACCCACU
CCCGACCCGGGGAGGUAGUGACGAAAAAUAACAAUACAGGACUCUUUCGAGGCCCUGUAA
UUGGAAUGAGUCCACUUUAAAUCCUUUAACGAGGAUCCAUUGGAGGGCAAGUCUGGUGCC
AGCAGCCGCGGUAAUUCCAGCUCCAAUAGCGUAUAUUAAAGUUGCUGCAGUUAAAAAGCU
CGUAGUUGGAUCUUGGGAGCGGCCGUCCCCUGCUCGGCGCCGGCCCGAAGCGUUUACUUU
GAAAAAAUUAGAGUGUUCAAAGCAGGCCGCCUGGAUACCGCAGCUAGGAAUAAUGGAAUA
GGACCGCGGUUCUAUUUUGUUGGUUUUCGGAACUGAGGCCAUGAUUAAGAGGGACGGCCG
GGGGCAUUCGUAUUGCGCCGCUAGAGGUGAAAUUCUUGGACCGGCGCAAGACGGACCAGA
GCGAAAGCAUUUGCCAAGAAUGUUUUCAUUAAUCAAGAACGAAAGUCGGAGGUUCGAAGA
CGAUCAGAUACCGUCGUAGUUCCGACCAUAAACGAUGCCGACUGGCGAUGCGGCGGCGUU
AUUCCCAUGACCCGCCGGGCAGCUUCCGGGAAACCAAAGUCUUUGGGUUCCGGGGGGAGU
AUGGUUGCAAAGCUGAAACUUAAAGGAAUUGACGGAAGGGCACCACCAGGAGUGGAGCCU
GCGGCUUAAUUUGACXCAACACGGGAAACCUCACCCGGCCCGGACACGGACAGGAUUGAC
AGAUUGAUAGCUCUUUCUCGAUUCCGUGGGUGGUGGUGCAUGGCNGUUCUUAGUUGGUGG
AGCGAUUUGUCUGGUUAAUUCCGAUAACGAACGAGACUCUGGCAUGCUAACUAGUUACGC
GACCCCGGUCGGCGUAACUUCUUAGAGGGACAAGUGGCGUUCAGCCACCCGAGAUUGAGC
AAUAACAGGUCUGUGAUGCCCUUAGAUGUCCGGGGCUGCACGCGCGCUACACUGACUGGC
UCAGCGUGUGCCUACCCUACGCCGGCAGGCGCGGGUAACCCGUUGAACCCCAUUCGUGAU
GGGGAUCGGGGAUUGCAAUUAUUCCCCAUGAACGAGGAAUUCCCAGUAAGUGCGGGUCAU
AAGCUUGCGUUGAUUAAGUCCCUGCCCUUUGUACACACCGCCCGUCGCUACUACCGAUUG
GAUGGUUUAGUGAGGCCCUCGGAUCGGCCCCGCCGGGGUGCCCUGGCGGAGCGCUGAGAA
GACGGUCGAACUUGACUAUCUAGAGGAAGUAAAAGUCGUAACAAGGUUUCNGUAGGUGAA
CCUGCGGAAGGAUCAUUA
Sequence of entity 7 (A), FASTA
>7UCJ_7 60S ribosomal protein L8 (chains A)
GRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKV
VFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPG
DRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILK
AGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAAR
RTGRLRGT
Sequence of entity 8 (B), FASTA
>7UCJ_8 60S ribosomal protein L3 (chains B)
SHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVD
RPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKN
WHKSKKKAFTKYCKKWQDDAGKRQLDKDFSSMKKYCQVIRVLAHTQMRLLPLRQKKAHLM
EIQVNGGTVAEKLDWARERLEQQVPVSQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLP
RKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKN
NASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALE
KIDLKFIDTTSKFGHGRFQTVEEKKAFMGPLKKD
Sequence of entity 9 (C), FASTA
>7UCJ_9 60S ribosomal protein L4 (chains C)
ACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGHQ
TSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKR
YAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDIK
KVYASQRMRAGKGKMRNRRRIQRRGPCVIYNEDNGIVKAFRNIPGITLLNVTKLNILKLA
PGGHVGRFCIWTESAFRKLDDLYGTWRKAASLKSNYNLPMHKMLNTDLSRILKSPEIQRA
LRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVERAAAALAAK
Sequence of entity 10 (D), FASTA
>7UCJ_10 Ribosomal_L18_c domain-containing protein (chains D)
FVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIIC
QIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQ
VEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPG
YDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKK
AHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQER
Sequence of entity 11 (E), FASTA
>7UCJ_11 60S ribosomal protein L6 (chains E)
GKPHCSRNPVLVRGIGRYSRSAMYSRKALYKRKYAAPKSRIERKKKREKVLATVTKPVGG
DKNGGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHR
GKRVVFLKQLSSGLLLVTGPLSLNRVPLRRTHQKFVIATSTKIDISGVKIPKHLTDAYFK
KKKLRKPRHQEGEIFDTEKEKYEITEQRKVDQKAVDSQILPKIKAVPQLQGYLRSVFALT
NGVYPHKLVF
Sequence of entity 12 (F), FASTA
>7UCJ_12 60S ribosomal protein L7 (chains F)
NFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYV
PAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWG
YPNLKSVNELIYKRGYGKINKKRIALTDNTLIARSLGKYNIICMEDLIHEIYTVGKHFKE
ANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 7 |
| MQ6 | Harringtonine | C28 H37 N O9 | 1 |
| MG | Magnesium ion | Mg | 296 |
Primary citation
Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine. Arango, D., Sturgill, D., Yang, R. et al. Mol Cell (2022) 82:2797-2814.e11. DOI 10.1016/j.molcel.2022.05.016 · PubMed
Other PDB entries of the same protein (UniProt G1TT27 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 11IQ 2.4 Å, Rabbit 80S with eEF2,eIF5A and SERBP1
- 8SCB 2.5 Å, Terminating ribosome with SRI-41315
- 9MR4 2.65 Å, NAC: Ribosome nascent chain complex(Oxa1L)
- 9RHU 2.65 Å, Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A…
- 8RJB 2.69 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8VVQ 2.7 Å, Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from…
- 8RJD 2.79 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8B6C 2.79 Å, Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative…
- 6SGC 2.8 Å, Rabbit 80S ribosome stalled on a poly(A) tail
- 7UCK 2.8 Å, 80S translation initiation complex with ac4c(-1) mRNA and Harringtonine
- 9BDL 2.8 Å, 80S ribosome with angiogenin
- 9QQA 2.8 Å, Ternary complex of translating ribosome, NAC and NMT1
Browse structure collections
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