7VVY: TRA module of NuA4
TRA module of NuA4. Determined by electron microscopy at 3.1 Å resolution. Released 10 Aug 2022.
- Method
- Electron microscopy
- Resolution
- 3.1 Å
- Organisms
- Saccharomyces cerevisiae S288C, Saccharomyces cerevisiae
- Chains
- 6
- Atoms
- 42,546
- Mol. weight
- 817.51 kDa
- Ligands
- ATP, MG
- Released
- 10 Aug 2022
Explore 7VVY in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7VVY contains 296 α-helices and 86 β-strands across 6 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain E: 20 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 226-228 | 3 | |
| α-helix | 242-247 | 6 | |
| β-strand | 268-273 | 6 | 1 |
| β-strand | 280-282 | 3 | 2 |
| α-helix | 287-294 | 8 | |
| α-helix | 299-301 | 3 | |
| α-helix | 313-336 | 24 | |
| β-strand | 345 | 1 | 3 |
| α-helix | 346-348 | 3 | |
| α-helix | 358-396 | 39 | |
| β-strand | 546-548 | 3 | 4 |
| α-helix | 549-551 | 3 | |
| α-helix | 554-562 | 9 | |
| β-strand | 566 | 1 | 4 |
| β-strand | 598 | 1 | 4 |
| β-strand | 599-604 | 6 | 1 |
| α-helix | 613-616 | 4 | |
| α-helix | 628-630 | 3 | |
| α-helix | 636-638 | 3 | |
| α-helix | 654-665 | 12 | |
| α-helix | 671-676 | 6 | |
| α-helix | 693-703 | 11 | |
| α-helix | 717-734 | 18 | |
| β-strand | 742-743 | 2 | 5 |
| α-helix | 745-747 | 3 | |
| α-helix | 750-752 | 3 | |
| α-helix | 757-771 | 15 | |
| α-helix | 797-806 | 10 | |
Chain F: 22 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 17-21 | 5 | 6 |
| β-strand | 25-30 | 6 | 6 |
| β-strand | 38-41 | 4 | 6 |
| β-strand | 43-44 | 2 | 7 |
| β-strand | 45-46 | 2 | 8 |
| β-strand | 55-56 | 2 | 8 |
| β-strand | 72-73 | 2 | 7 |
| β-strand | 75-76 | 2 | 9 |
| β-strand | 79-80 | 2 | 9 |
| α-helix | 83-97 | 15 | |
| β-strand | 108-112 | 5 | 6 |
| α-helix | 118-126 | 9 | |
| α-helix | 127-131 | 5 | |
| β-strand | 136-141 | 6 | 6 |
| α-helix | 142-150 | 9 | |
| β-strand | 155-160 | 6 | 10 |
| β-strand | 165-171 | 7 | 10 |
| β-strand | 174-175 | 2 | 10 |
| α-helix | 177-179 | 3 | |
| β-strand | 181-183 | 3 | 10 |
| α-helix | 187-197 | 11 | |
| α-helix | 206-208 | 3 | |
| β-strand | 209-211 | 3 | 11 |
| β-strand | 217-218 | 2 | 11 |
| α-helix | 224-226 | 3 | |
| α-helix | 227-234 | 8 | |
| α-helix | 235-239 | 5 | |
| α-helix | 240-246 | 7 | |
| α-helix | 258-263 | 6 | |
| α-helix | 266-267 | 2 | |
| β-strand | 268-271 | 4 | 12 |
| β-strand | 277-280 | 4 | 12 |
| α-helix | 282-290 | 9 | |
| α-helix | 385-394 | 10 | |
| α-helix | 401-406 | 6 | |
| β-strand | 408-411 | 4 | 10 |
| α-helix | 414-416 | 3 | |
| α-helix | 420-431 | 12 | |
| α-helix | 445-449 | 5 | |
| α-helix | 451-460 | 10 | |
| α-helix | 466-468 | 3 | |
| β-strand | 470-471 | 2 | 6 |
| α-helix | 472-478 | 7 | |
Chain G: 23 helices, 19 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-7 | 2 | |
| β-strand | 8-12 | 5 | 13 |
| β-strand | 16-21 | 6 | 13 |
| β-strand | 29-32 | 4 | 13 |
| β-strand | 35-36 | 2 | 14 |
| β-strand | 53-54 | 2 | 14 |
| α-helix | 56-60 | 5 | |
| β-strand | 68 | 1 | 14 |
| β-strand | 71-72 | 2 | 15 |
| β-strand | 75-76 | 2 | 15 |
| α-helix | 79-88 | 10 | |
| α-helix | 89-93 | 5 | |
| α-helix | 98-100 | 3 | |
| β-strand | 103-107 | 5 | 13 |
| α-helix | 113-121 | 9 | |
| α-helix | 122-126 | 5 | |
| β-strand | 131-136 | 6 | 13 |
| α-helix | 137-144 | 8 | |
| β-strand | 150-155 | 6 | 16 |
| β-strand | 160-166 | 7 | 16 |
| β-strand | 169-170 | 2 | 16 |
| α-helix | 172-174 | 3 | |
| β-strand | 176-178 | 3 | 16 |
| α-helix | 182-193 | 12 | |
| α-helix | 194-196 | 3 | |
| α-helix | 206-216 | 11 | |
| α-helix | 223-232 | 10 | |
| β-strand | 238-241 | 4 | 17 |
| β-strand | 247-250 | 4 | 17 |
| α-helix | 256-259 | 4 | |
| α-helix | 274-283 | 10 | |
| α-helix | 291-294 | 4 | |
| β-strand | 297-300 | 4 | 16 |
| α-helix | 302-304 | 3 | |
| α-helix | 309-320 | 12 | |
| β-strand | 329-330 | 2 | 16 |
| α-helix | 335-337 | 3 | |
| α-helix | 338-347 | 10 | |
| α-helix | 351-354 | 4 | |
| β-strand | 357-358 | 2 | 13 |
| α-helix | 359-365 | 7 | |
| α-helix | 369-373 | 5 | |
Chain H: 15 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 489-490 | 2 | 5 |
| α-helix | 493-495 | 3 | |
| α-helix | 505-530 | 26 | |
| β-strand | 535 | 1 | 3 |
| β-strand | 546-549 | 4 | 19 |
| α-helix | 560-562 | 3 | |
| α-helix | 564-567 | 4 | |
| β-strand | 572-576 | 5 | 19 |
| α-helix | 581-586 | 6 | |
| β-strand | 593-595 | 3 | 1 |
| β-strand | 601 | 1 | 1 |
| α-helix | 611-615 | 5 | |
| α-helix | 617 | 1 | |
| β-strand | 618-620 | 3 | 2 |
| β-strand | 632-633 | 2 | 1 |
| α-helix | 634 | 1 | |
| β-strand | 636-642 | 7 | 4 |
| β-strand | 648-654 | 7 | 4 |
| α-helix | 667-670 | 4 | |
| α-helix | 673-680 | 8 | |
| β-strand | 692-693 | 2 | 12 |
| α-helix | 694-696 | 3 | |
| α-helix | 698-710 | 13 | |
| α-helix | 714-716 | 3 | |
| α-helix | 725-730 | 6 | |
| α-helix | 735-765 | 31 | |
Chain K: 15 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 43-49 | 7 | |
| β-strand | 57-60 | 4 | 4 |
| α-helix | 75-77 | 3 | |
| β-strand | 78-84 | 7 | 18 |
| β-strand | 90-96 | 7 | 18 |
| β-strand | 108 | 1 | 18 |
| α-helix | 110-114 | 5 | |
| α-helix | 125-131 | 7 | |
| α-helix | 166-178 | 13 | |
| α-helix | 183-189 | 7 | |
| α-helix | 199-215 | 17 | |
| α-helix | 221-224 | 4 | |
| α-helix | 230-244 | 15 | |
| α-helix | 248-265 | 18 | |
| α-helix | 268-282 | 15 | |
| α-helix | 291-295 | 5 | |
| α-helix | 297-308 | 12 | |
| α-helix | 322-324 | 3 | |
| α-helix | 325-328 | 4 | |
Chain L: 201 helices, 23 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 4-9 | 6 | |
| α-helix | 28-30 | 3 | |
| α-helix | 45-60 | 16 | |
| α-helix | 73-85 | 13 | |
| α-helix | 92-96 | 5 | |
| α-helix | 100-103 | 4 | |
| α-helix | 118-131 | 14 | |
| α-helix | 141-156 | 16 | |
| α-helix | 232-242 | 11 | |
| α-helix | 251-253 | 3 | |
| α-helix | 294-308 | 15 | |
| α-helix | 311-313 | 3 | |
| α-helix | 325-334 | 10 | |
| α-helix | 342-355 | 14 | |
| α-helix | 360-368 | 9 | |
| α-helix | 375-377 | 3 | |
| α-helix | 388-402 | 15 | |
| α-helix | 408-423 | 16 | |
| α-helix | 429-452 | 24 | |
| α-helix | 454-456 | 3 | |
| α-helix | 457-479 | 23 | |
| α-helix | 482-500 | 19 | |
| α-helix | 513-519 | 7 | |
| α-helix | 562-566 | 5 | |
| α-helix | 573-575 | 3 | |
| α-helix | 579-600 | 22 | |
| α-helix | 601-604 | 4 | |
| α-helix | 605-607 | 3 | |
| β-strand | 619 | 1 | 20 |
| β-strand | 623 | 1 | 20 |
| α-helix | 628-643 | 16 | |
| α-helix | 644-646 | 3 | |
| α-helix | 677-689 | 13 | |
| α-helix | 695-713 | 19 | |
| α-helix | 717-719 | 3 | |
| α-helix | 720-727 | 8 | |
| α-helix | 733-747 | 15 | |
| α-helix | 748-750 | 3 | |
| α-helix | 756-775 | 20 | |
| α-helix | 789-798 | 10 | |
| α-helix | 807-818 | 12 | |
| α-helix | 828-830 | 3 | |
| α-helix | 832-843 | 12 | |
| α-helix | 854-862 | 9 | |
| α-helix | 880-889 | 10 | |
| α-helix | 894-906 | 13 | |
| α-helix | 914-917 | 4 | |
| α-helix | 918-920 | 3 | |
| α-helix | 921-930 | 10 | |
| α-helix | 943-951 | 9 | |
| β-strand | 977-980 | 4 | 21 |
| β-strand | 982 | 1 | 22 |
| β-strand | 989-992 | 4 | 21 |
| α-helix | 997-1005 | 9 | |
| α-helix | 1012-1029 | 18 | |
| α-helix | 1030-1032 | 3 | |
| α-helix | 1039-1048 | 10 | |
| α-helix | 1069-1089 | 21 | |
| α-helix | 1096-1121 | 26 | |
| β-strand | 1140 | 1 | 23 |
| α-helix | 1149-1153 | 5 | |
| α-helix | 1158-1179 | 22 | |
| α-helix | 1181-1187 | 7 | |
| α-helix | 1189-1200 | 12 | |
| α-helix | 1206-1222 | 17 | |
| α-helix | 1229-1232 | 4 | |
| α-helix | 1234-1246 | 13 | |
| α-helix | 1254-1271 | 18 | |
| α-helix | 1284-1293 | 10 | |
| α-helix | 1301-1315 | 15 | |
| α-helix | 1322-1325 | 4 | |
| α-helix | 1330-1339 | 10 | |
| α-helix | 1347-1362 | 16 | |
| α-helix | 1372-1382 | 11 | |
| α-helix | 1405-1423 | 19 | |
| α-helix | 1437-1446 | 10 | |
| α-helix | 1453-1466 | 14 | |
| α-helix | 1467-1469 | 3 | |
| α-helix | 1478-1481 | 4 | |
| α-helix | 1483-1488 | 6 | |
| α-helix | 1497-1507 | 11 | |
| α-helix | 1518-1529 | 12 | |
| α-helix | 1533-1537 | 5 | |
| α-helix | 1547-1557 | 11 | |
| α-helix | 1571-1583 | 13 | |
| α-helix | 1594-1603 | 10 | |
| α-helix | 1606-1612 | 7 | |
| α-helix | 1618-1628 | 11 | |
| α-helix | 1631-1633 | 3 | |
| α-helix | 1634-1640 | 7 | |
| α-helix | 1644-1658 | 15 | |
| α-helix | 1662-1678 | 17 | |
| α-helix | 1691-1708 | 18 | |
| α-helix | 1716-1733 | 18 | |
| α-helix | 1740-1749 | 10 | |
| α-helix | 1763-1769 | 7 | |
| α-helix | 1772-1774 | 3 | |
| α-helix | 1778-1791 | 14 | |
| α-helix | 1797-1816 | 20 | |
| α-helix | 1834-1842 | 9 | |
| α-helix | 1847-1849 | 3 | |
| α-helix | 1859-1874 | 16 | |
| α-helix | 1883-1892 | 10 | |
| α-helix | 1900-1915 | 16 | |
| α-helix | 1921-1930 | 10 | |
| α-helix | 1936-1938 | 3 | |
| α-helix | 1939-1957 | 19 | |
| α-helix | 1965-1974 | 10 | |
| α-helix | 1983-1987 | 5 | |
| α-helix | 2002-2014 | 13 | |
| α-helix | 2025-2042 | 18 | |
| α-helix | 2091-2106 | 16 | |
| α-helix | 2117-2128 | 12 | |
| α-helix | 2156-2172 | 17 | |
| α-helix | 2184-2195 | 12 | |
| α-helix | 2204-2216 | 13 | |
| α-helix | 2229-2244 | 16 | |
| α-helix | 2252-2266 | 15 | |
| α-helix | 2276-2289 | 14 | |
| α-helix | 2303-2320 | 18 | |
| α-helix | 2329-2341 | 13 | |
| α-helix | 2346-2360 | 15 | |
| α-helix | 2370-2377 | 8 | |
| α-helix | 2378-2381 | 4 | |
| α-helix | 2382-2385 | 4 | |
| α-helix | 2388-2403 | 16 | |
| α-helix | 2413-2423 | 11 | |
| α-helix | 2429-2442 | 14 | |
| α-helix | 2447-2452 | 6 | |
| α-helix | 2453-2457 | 5 | |
| α-helix | 2469-2476 | 8 | |
| α-helix | 2477-2479 | 3 | |
| β-strand | 2480 | 1 | 22 |
| β-strand | 2488 | 1 | 21 |
| β-strand | 2494 | 1 | 23 |
| α-helix | 2495-2496 | 2 | |
| α-helix | 2500-2502 | 3 | |
| α-helix | 2519-2533 | 15 | |
| α-helix | 2538-2549 | 12 | |
| α-helix | 2553-2567 | 15 | |
| α-helix | 2568-2570 | 3 | |
| α-helix | 2576-2587 | 12 | |
| α-helix | 2590-2595 | 6 | |
| α-helix | 2602-2610 | 9 | |
| α-helix | 2624-2626 | 3 | |
| α-helix | 2633-2641 | 9 | |
| α-helix | 2655-2668 | 14 | |
| α-helix | 2672-2682 | 11 | |
| α-helix | 2686-2697 | 12 | |
| α-helix | 2700-2715 | 16 | |
| α-helix | 2721-2723 | 3 | |
| α-helix | 2725-2739 | 15 | |
| α-helix | 2743-2751 | 9 | |
| α-helix | 2758-2760 | 3 | |
| α-helix | 2773-2783 | 11 | |
| α-helix | 2789-2805 | 17 | |
| α-helix | 2813-2830 | 18 | |
| α-helix | 2835-2836 | 2 | |
| α-helix | 2838-2863 | 26 | |
| α-helix | 2865-2867 | 3 | |
| α-helix | 2874-2885 | 12 | |
| α-helix | 2895-2915 | 21 | |
| α-helix | 2921-2923 | 3 | |
| α-helix | 2943-2956 | 14 | |
| α-helix | 2960-2966 | 7 | |
| α-helix | 2980-2991 | 12 | |
| α-helix | 2996-2998 | 3 | |
| α-helix | 2999-3006 | 8 | |
| α-helix | 3017-3032 | 16 | |
| α-helix | 3037-3047 | 11 | |
| α-helix | 3054-3068 | 15 | |
| α-helix | 3077-3090 | 14 | |
| α-helix | 3098-3108 | 11 | |
| α-helix | 3116-3122 | 7 | |
| α-helix | 3130-3136 | 7 | |
| α-helix | 3137-3141 | 5 | |
| α-helix | 3152-3162 | 11 | |
| α-helix | 3164-3179 | 16 | |
| α-helix | 3203-3217 | 15 | |
| α-helix | 3220-3236 | 17 | |
| α-helix | 3241-3262 | 22 | |
| α-helix | 3264 | 1 | |
| α-helix | 3274-3286 | 13 | |
| α-helix | 3292-3301 | 10 | |
| α-helix | 3309-3326 | 18 | |
| β-strand | 3331-3332 | 2 | 24 |
| α-helix | 3334-3337 | 4 | |
| α-helix | 3339-3342 | 4 | |
| α-helix | 3344-3347 | 4 | |
| α-helix | 3352 | 1 | |
| β-strand | 3353 | 1 | 25 |
| α-helix | 3354 | 1 | |
| α-helix | 3368-3369 | 2 | |
| β-strand | 3370 | 1 | 25 |
| β-strand | 3371-3374 | 4 | 24 |
| β-strand | 3378-3382 | 5 | 24 |
| β-strand | 3387-3395 | 9 | 24 |
| β-strand | 3400-3406 | 7 | 24 |
| α-helix | 3413-3425 | 13 | |
| α-helix | 3426-3428 | 3 | |
| α-helix | 3429-3432 | 4 | |
| α-helix | 3434-3438 | 5 | |
| β-strand | 3448-3450 | 3 | 24 |
| β-strand | 3456-3459 | 4 | 24 |
| β-strand | 3464-3466 | 3 | 26 |
| α-helix | 3467-3477 | 11 | |
| α-helix | 3484-3495 | 12 | |
| α-helix | 3506-3520 | 15 | |
| α-helix | 3526-3534 | 9 | |
| α-helix | 3538-3560 | 23 | |
| α-helix | 3561-3563 | 3 | |
| β-strand | 3564 | 1 | 27 |
| β-strand | 3572-3575 | 4 | 26 |
| β-strand | 3581-3583 | 3 | 26 |
| β-strand | 3588 | 1 | 27 |
| α-helix | 3626-3632 | 7 | |
| α-helix | 3635-3636 | 2 | |
| α-helix | 3637-3641 | 5 | |
| α-helix | 3642-3653 | 12 | |
| α-helix | 3659-3677 | 19 | |
| α-helix | 3686-3704 | 19 | |
| α-helix | 3708-3710 | 3 | |
| α-helix | 3719-3726 | 8 | |
| α-helix | 3730-3733 | 4 | |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Chromatin modification-related protein EAF1 | E | protein | 1168 | Saccharomyces cerevisiae S288C | Q06337 (AlphaFold model) |
| Actin-related protein 4 | F | protein | 489 | Saccharomyces cerevisiae S288C | P80428 (AlphaFold model) |
| Actin | G | protein | 375 | Saccharomyces cerevisiae S288C | P60010 (AlphaFold model) |
| SWR1-complex protein 4 | K | protein | 476 | Saccharomyces cerevisiae S288C | P53201 (AlphaFold model) |
| Enhancer of polycomb-like protein 1 | H | protein | 832 | Saccharomyces cerevisiae S288C | P43572 |
| Transcription-associated protein 1 | L | protein | 3744 | Saccharomyces cerevisiae | P38811 |
Sequence of entity 1 (E), FASTA
>7VVY_1 Chromatin modification-related protein EAF1 (chains E)
MSSRPSSAVPNSASLSEDQSSDRSKFPKADDLIDERDRKLTELYCVSRLNQLLELTDENK
LRKEIDAFLKKNDIRRGIRFDEASLPKLLHTAATPITKKKLKDVNLINVPNQRLSDSKMS
RELPENSENVSVKSESHFVPSHDNSIRENMMDSLRPAEKTGGMWNKRPLESTMGGEEERH
EKRQKMQSQSLESSNNSEMASLPISPRPPVPNALAHYTYYENIEYPPADPTEVQPAVKFK
DPLIKNIMAKEIDTSDHYNENNVDALETVFLLMNDYIPSKIPQALPLAELKYMSQTLPLI
NLIPRAHKALTTNIINNALNEARITVVGSRIEELRRLGLWSLRQPKRFIDPWKQHNTHQN
ILLEEAKWMQADFKEGHKYKVAICTAMAQAIKDYWTYGEICCVKRKTLLPGKENKLSDDG
RISEKSGRPSDTSRNDSDISIAGKDDIGIIANVDDITEKESAAANDNDENGKNEAGAKSD
FDFADGLLSQEGAHDQIISSIDTKLLLKKPSSSSEVVLIQHEVAASSALIETEESKKELA
PPFKLSIFVDELNTFEKTLIQDLPLYNGINEERPKKDDSLPFIPISKSVVSLDDNGFYKL
LERQLIDEEPSISQLSKRRGMFYGNRRNHYLRPPAVPSLRYLQNRTPTIWLSEDDQELVK
NINTYGYNWELISAHMTHRLTYSYLSNIERRTPWQCFERFVQLNERFNFSDLKGPRAHSA
QQWLIEAHKFQQRQNRRISPLGVNTESIQRGHRRLRWASMFEAIRKCMKKRENTPRPNPT
QPRKPLDCKNMKVPTPAEMSLLKAQRDEALRRDIQLRRTVKNRLQQRQQQSQQAHSSRAQ
SPIPSNGKSSSNLARNGQASAPRPNQKQYTEQDIIESYSRKLLEQKPDIGPEMALKAAKN
YYRTLREQQQQLKQHQIQQQRQQLQEESSHVQQLQQLQPGSQAPPPKSSPSQSSLSNISN
INSAPRIKSPTPQEILQRFQKQRTLQVDWSHPQFEKHHHHHHHHHHHHDYDIPTTASVDG
SENLYFQGSPQQNKTAALAQHDEAVDNKFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKD
DPSQSANLLAEAKKLNDAQAPKVDNKFNKEQQNAFYEILHLPNLNEEQRNAFIQSLKDDP
SQSANLLAEAKKLNDAQAPKVDANSAAL
Sequence of entity 2 (F), FASTA
>7VVY_2 Actin-related protein 4 (chains F)
MSNAALQVYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIFSEQ
SIGIPRKDYELKPIIENGLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNSTEN
RKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKST
RRNFIAGKFINHLIKKALEPKEIIPLFAIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQ
ECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLPKEDDI
PANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTPTEEKEQEAVSKSTSPAANSAD
TPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGL
SDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQLWVGKKEYEEVGV
ERLLNDRFR
Sequence of entity 3 (G), FASTA
>7VVY_3 Actin (chains G)
MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQS
KRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMT
QIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDL
AGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSY
ELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMS
GGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQ
EYDESGPSIVHHKCF
Sequence of entity 4 (K), FASTA
>7VVY_4 SWR1-complex protein 4 (chains K)
MSSSDIFDVLNIKQKSRSPTNGQVSVPSSSAANRPKPQVTGMQRELFNLLGENQPPVVIK
SGNNFKEKMLSTSKPSPWSFVEFKANNSVTLRHWVKGSKELIGDTPKESPYSKFNQHLSI
PSFTKEEYEAFMNENEGTQKSVESEKNHNENFTNEKKDESKNSWSFEEIEYLFNLCKKYD
LRWFLIFDRYSYNNSRTLEDLKEKFYYTCRNYFKASDPSNPLLSSLNFSAEKEIERKKYL
QRLLSRSAAEIAEEEALVVESKKFEMAAKRTLAERESLLRLLDSPHSDQTITQYLTSQGM
SQLYNALLADKTRKRKHDLNIPENPWMKQQQQFAQHRQLQQLNVKKSEVKENLSPKKTKR
QRQEMQTALKRKSESAYAEQLLKDFNSDERKALGVITHGEKLSPGVYLRSTKLSTFKPAL
QNKILAILQELSLPSRPVMPSFDVMERQEELLKKINTLIDLKKHVDKYEAGMSITK
Sequence of entity 5 (H), FASTA
>7VVY_5 Enhancer of polycomb-like protein 1 (chains H)
MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKI
SVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMGSGHTKHKDY
IPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGS
SDILTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEELKPTLIKSDMADFNLRNQLNH
EINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERP
GEKEEIDPYVCFRRREVRHPRKTRRIDILNSQRLRALHQELKNAKDLALLVAKRENVSLN
WINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAA
AAAAAAKAKNNKRNNQLEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGKQLANASSSST
SQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEKRKIEDADVFFNLTD
DPFNPVFDMSLPKNFSTSNVPFASIASSKFQIDRSFYSSHLPEYLKGISDDIRIYDSNGR
SRNKDNYNLDTKRIKKTELYDPFQENLEIHSREYPIKFRKRVGRSNIKYVDRMPNFTTSS
TKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDSPQNEYGI
KFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLKQKHIQHLQQQQ
QQQQQQQQQAQQQKQKSQNNNSNSSNSLKKLNDSLINSEAKQNSSITQKNSS
Sequence of entity 6 (L), FASTA
>7VVY_6 Transcription-associated protein 1 (chains L)
MSLTEQIEQFASRFRDDDATLQSRYSTLSELYDIMELLNSPEDYHFFLQAVIPLLLNQLK
EVPISYDAHSPEQKLRNSMLDIFNRCLMNQTFQPYAMEVLEFLLSVLPKENEENGILCMK
VLTTLFKSFKSILQDKLDSFIRIIIQIYKNTPNLINQTFYEAGKAEQGDLDSPKEPQADE
LLDEFSKNDEEKDFPSKQSSTEPRFENSTSSNGLRSSMFSFKILSECPITMVTLYSSYKQ
LTSTSLPEFTPLIMNLLNIQIKQQQEAREQAESRGEHFTSISTEIINRPAYCDFILAQIK
ATSFLAYVFIRGYAPEFLQDYVNFVPDLIIRLLQDCPSELSSARKELLHATRHILSTNYK
KLFLPKLDYLFDERILIGNGFTMHETLRPLAYSTVADFIHNIRSELQLSEIEKTIKIYTG
YLLDESLALTVQIMSAKLLLNLVERILKLGKENPQEAPRAKKLLMIIIDSYMNRFKTLNR
QYDTIMKYYGRYETHKKEKAEKLKNSIQDNDKESEEFMRKVLEPSDDDHLMPQPKKEDIN
DSPDVEMTESDKVVKNDVEMFDIKNYAPILLLPTPTNDPIKDAFYLYRTLMSFLKTIIHD
LKVFNPPPNEYTVANPKLWASVSRVFSYEEVIVFKDLFHECIIGLKFFKDHNEKLSPETT
KKHFDISMPSLPVSATKDARELMDYLAFMFMQMDNATFNEIIEQELPFVYERMLEDSGLL
HVAQSFLTSEITSPNFAGILLRFLKGKLKDLGNVDFNTSNVLIRLFKLSFMSVNLFPNIN
EVVLLPHLNDLILNSLKYSTTAEEPLVYFYLIRTLFRSIGGGRFENLYRSIKPILQVLLQ
SLNQMILTARLPHERELYVELCITVPVRLSVLAPYLPFLMKPLVFALQQYPDLVSQGLRT
LELCIDNLTAEYFDPIIEPVIDDVSKALFNLLQPQPFNHAISHNVVRILGKLGGRNRQFL
KPPTDLTEKTELDIDAIADFKINGMPEDVPLSVTPGIQSALNILQSYKSDIHYRKSAYKY
LTCVLLLMTKSSAEFPTNYTELLKTAVNSIKLERIGIEKNFDLEPTVNKRDYSNQENLFL
RLLESVFYATSIKELKDDAMDLLNNLLDHFCLLQVNTTLLNKRNYNGTFNIDLKNPNFML
DSSLILDAIPFALSYYIPEVREVGVLAYKRIYEKSCLIYGEELALSHSFIPELAKQFIHL
CYDETYYNKRGGVLGIKVLIDNVKSSSVFLKKYQYNLANGLLFVLKDTQSEAPSAITDSA
EKLLIDLLSITFADVKEEDLGNKVLENTLTDIVCELSNANPKVRNACQKSLHTISNLTGI
PIVKLMDHSKQFLLSPIFAKPLRALPFTMQIGNVDAITFCLSLPNTFLTFNEELFRLLQE
SIVLADAEDESLSTNIQKTTEYSTSEQLVQLRIACIKLLAIALKNEEFATAQQGNIRIRI
LAVFFKTMLKTSPEIINTTYEALKGSLAENSKLPKELLQNGLKPLLMNLSDHQKLTVPGL
DALSKLLELLIAYFKVEIGRKLLDHLTAWCRVEVLDTLFGQDLAEQMPTKIIVSIINIFH
LLPPQADMFLNDLLLKVMLLERKLRLQLDSPFRTPLARYLNRFHNPVTEYFKKNMTLRQL
VLFMCNIVQRPEAKELAEDFEKELDNFYDFYISNIPKNQVRVVSFFTNMVDLFNTMVITN
GDEWLKKKGNMILKLKDMLNLTLKTIKENSFYIDHLQLNQSIAKFQALYLRFTELSERDQ
NPLLLDFIDFSFSNGIKASYSLKKFIFHNIIASSNKEKQNNFINDATLFVLSDKCLDARI
FVLKNVINSTLIYEVATSGSLKSYLVEDKKPKWLELLHNKIWKNSNAILAYDVLDHHDLF
RFELLQLSAIFIKADPEIIAEIKKDIIKFCWNFIKLEDTLIKQSAYLVTSYFISKFDFPI
KVVTQVFVALLRSSHVEARYLVKQSLDVLTPVLHERMNAAGTPDTWINWVKRVMVENSSS
QNNILYQFLISHPDLFFNSRDLFISNIIHHMNKITFMSNSNSDSHTLAIDLASLILYWEN
KTLEITNVNNTKTDSDGDVVMSDSKSDINPVEADTTAIIVDANNNSPISLHLREACTAFL
IRYVCASNHRAIETELGLRAINILSELISDKHWTNVNVKLVYFEKFLIFQDLDSENILYY
CMNALDVLYVFFKNKTKEWIMENLPTIQNLLEKCIKSDHHDVQEALQKVLQVIMKAIKAQ
GVSVIIEEESPGKTFIQMLTSVITQDLQETSSVTAGVTLAWVLFMNFPDNIVPLLTPLMK
TFSKLCKDHLSISQPKDAMALEEARITTKLLEKVLYILSLKVSLLGDSRRPFLSTVALLI
DHSMDQNFLRKIVNMSRSWIFNTEIFPTVKEKAAILTKMLAFEIRGEPSLSKLFYEIVLK
LFDQEHFNNTEITVRMEQPFLVGTRVEDIGIRKRFMTILDNSLERDIKERLYYVIRDQNW
EFIADYPWLNQALQLLYGSFNREKELSLKNIYCLSPPSILQEYLPENAEMVTEVNDLELS
NFVKGHIASMQGLCRIISSDFIDSLIEIFYQDPKAIHRAWVTLFPQVYKSIPKNEKYGFV
RSIITLLSKPYHTRQISSRTNVINMLLDSISKIESLELPPHLVKYLAISYNAWYQSINIL
ESIQSNTSIDNTKIIEANEDALLELYVNLQEEDMFYGLWRRRAKYTETNIGLSYEQIGLW
DKAQQLYEVAQVKARSGALPYSQSEYALWEDNWIQCAEKLQHWDVLTELAKHEGFTDLLL
ECGWRVADWNSDRDALEQSVKSVMDVPTPRRQMFKTFLALQNFAESRKGDQEVRKLCDEG
IQLSLIKWVSLPIRYTPAHKWLLHGFQQYMEFLEATQIYANLHTTTVQNLDSKAQEIKRI
LQAWRDRLPNTWDDVNMWNDLVTWRQHAFQVINNAYLPLIPALQQSNSNSNINTHAYRGY
HEIAWVINRFAHVARKHNMPDVCISQLARIYTLPNIEIQEAFLKLREQAKCHYQNMNELT
TGLDVISNTNLVYFGTVQKAEFFTLKGMFLSKLRAYEEANQAFATAVQIDLNLAKAWAQW
GFFNDRRLSEEPNNISFASNAISCYLQAAGLYKNSKIRELLCRILWLISIDDASGMLTNA
FDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILIRIAKSYPQALHFQLRTTKEDFAV
IQRQTMAVMGDKPDTNDRNGRRQPWEYLQELNNILKTAYPLLALSLESLVAQINDRFKST
TDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNADF
IDNKPDYETYIKRLRYWRRRLENKLDRASKKENLEVLCPHLSNFHHQKFEDIEIPGQYLL
NKDNNVHFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMF
QLYRLFNKSLSKNVETRRRSIQFNLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGF
DPDDIQDFMADKLNAAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFED
FWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYERVKPLL
KNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELN
TYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVDLIIRKVAQLGHLNSTPTVTTQFI
LDCIGSAVSPRNLARTDVNFMPWF
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ATP | Adenosine-5'-triphosphate | C10 H16 N5 O13 P3 | 2 |
| MG | Magnesium ion | Mg | 2 |
Primary citation
Structure of the NuA4 acetyltransferase complex bound to the nucleosome. Qu, K., Chen, K., Wang, H. et al. Nature (2022) 610:569-574. DOI 10.1038/s41586-022-05303-x · PubMed
Other PDB entries of the same protein (UniProt Q06337 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8ESC 3.1 Å, Structure of the Yeast NuA4 Histone Acetyltransferase Complex
- 7YFN 3.8 Å, Core module of the NuA4 complex in S. cerevisiae
- 7YFP 4.0 Å, The NuA4 histone acetyltransferase complex from S. cerevisiae
- 5Y81 4.7 Å, NuA4 TEEAA sub-complex
- 7VVZ 8.8 Å, NuA4 bound to the nucleosome
Browse structure collections
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