8B6C: Ribosome-Sec61
Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147. Determined by electron microscopy at 2.79 Å resolution. Released 22 Feb 2023.
- Method
- Electron microscopy
- Resolution
- 2.79 Å
- Organism
- Oryctolagus cuniculus
- Chains
- 47
- Atoms
- 139,959
- Mol. weight
- 2505.61 kDa
- Ligands
- MG, ZN, OWI
- Released
- 22 Feb 2023
Explore 8B6C in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8B6C contains 344 α-helices and 303 β-strands across 44 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 8 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 7-10 | 4 | |
| α-helix | 42-48 | 7 | |
| α-helix | 65-68 | 4 | |
| β-strand | 72-74 | 3 | 37 |
| α-helix | 75-78 | 4 | |
| α-helix | 84-92 | 9 | |
| β-strand | 97-98 | 2 | 38 |
| β-strand | 100-102 | 3 | 39 |
| α-helix | 103-106 | 4 | |
| β-strand | 110-112 | 3 | 37 |
| β-strand | 122-126 | 5 | 39 |
| β-strand | 128-129 | 2 | 37 |
| α-helix | 131-140 | 10 | |
| β-strand | 142-146 | 5 | 39 |
Chain A: 14 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-5 | 3 | |
| α-helix | 6-9 | 4 | |
| α-helix | 10-12 | 3 | |
| α-helix | 29-32 | 4 | |
| α-helix | 34-38 | 5 | |
| β-strand | 40-49 | 10 | 60 |
| β-strand | 58-64 | 7 | 60 |
| β-strand | 71-77 | 7 | 60 |
| β-strand | 79 | 1 | 61 |
| β-strand | 83 | 1 | 62 |
| β-strand | 87-91 | 5 | 60 |
| α-helix | 95-96 | 2 | |
| β-strand | 101-103 | 3 | 60 |
| α-helix | 108 | 1 | |
| β-strand | 112-114 | 3 | 60 |
| β-strand | 116 | 1 | 63 |
| β-strand | 126 | 1 | 63 |
| β-strand | 134-140 | 7 | 60 |
| α-helix | 142-144 | 3 | |
| β-strand | 145-149 | 5 | 60 |
| β-strand | 155-159 | 5 | 60 |
| β-strand | 163-166 | 4 | 60 |
| β-strand | 169 | 1 | 61 |
| α-helix | 174-176 | 3 | |
| α-helix | 182-192 | 11 | |
| α-helix | 198-200 | 3 | |
| α-helix | 201-203 | 3 | |
| α-helix | 206-208 | 3 | |
| β-strand | 224-225 | 2 | 64 |
| α-helix | 229-230 | 2 | |
| β-strand | 237-238 | 2 | 64 |
Chain b: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-17 | 6 | |
| α-helix | 22-24 | 3 | |
| α-helix | 37-49 | 13 | |
| α-helix | 50-53 | 4 | |
| α-helix | 54-75 | 22 | |
| α-helix | 91-100 | 10 | |
| α-helix | 106-116 | 11 | |
Chain B: 17 helices, 20 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-10 | 2 | |
| α-helix | 14-16 | 3 | |
| α-helix | 32-35 | 4 | |
| α-helix | 40-41 | 2 | |
| β-strand | 42-43 | 2 | 29 |
| β-strand | 45-59 | 15 | 30 |
| β-strand | 71-80 | 10 | 30 |
| α-helix | 82-83 | 2 | |
| β-strand | 84-95 | 12 | 31 |
| β-strand | 98-106 | 9 | 31 |
| α-helix | 112-115 | 4 | |
| α-helix | 116-118 | 3 | |
| α-helix | 133-137 | 5 | |
| α-helix | 140-156 | 17 | |
| β-strand | 159-165 | 7 | 31 |
| α-helix | 168-170 | 3 | |
| β-strand | 180-184 | 5 | 31 |
| β-strand | 185-186 | 2 | 29 |
| α-helix | 190-200 | 11 | |
| β-strand | 203-205 | 3 | 31 |
| α-helix | 207-209 | 3 | |
| β-strand | 216-222 | 7 | 30 |
| α-helix | 223-225 | 3 | |
| β-strand | 227-229 | 3 | 32 |
| α-helix | 231-234 | 4 | |
| α-helix | 237-241 | 5 | |
| β-strand | 270-272 | 3 | 32 |
| β-strand | 276-287 | 12 | 30 |
| β-strand | 292-293 | 2 | 33 |
| β-strand | 298-299 | 2 | 33 |
| β-strand | 320 | 1 | 34 |
| β-strand | 324 | 1 | 34 |
| β-strand | 330-334 | 5 | 30 |
| β-strand | 344-349 | 6 | 30 |
| α-helix | 357-360 | 4 | |
| β-strand | 365-368 | 4 | 30 |
| α-helix | 382-389 | 8 | |
Chain c: 5 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-24 | 13 | |
| β-strand | 26-29 | 4 | 52 |
| α-helix | 32-40 | 9 | |
| β-strand | 45-48 | 4 | 52 |
| α-helix | 54-67 | 14 | |
| β-strand | 70-73 | 4 | 52 |
| α-helix | 78-85 | 8 | |
| β-strand | 93-98 | 6 | 52 |
| α-helix | 104-106 | 3 | |
Chain C: 21 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 7-11 | 5 | 9 |
| α-helix | 12 | 1 | |
| β-strand | 17-23 | 7 | 9 |
| α-helix | 24-25 | 2 | |
| α-helix | 26-29 | 4 | |
| α-helix | 31-32 | 2 | |
| α-helix | 34-44 | 11 | |
| β-strand | 64-66 | 3 | 10 |
| β-strand | 77-79 | 3 | 10 |
| α-helix | 100-101 | 2 | |
| α-helix | 117-130 | 14 | |
| α-helix | 134-139 | 6 | |
| β-strand | 152-154 | 3 | 9 |
| α-helix | 156-160 | 5 | |
| α-helix | 164-173 | 10 | |
| α-helix | 177-186 | 10 | |
| β-strand | 188-189 | 2 | 11 |
| α-helix | 193-197 | 5 | |
| β-strand | 201-202 | 2 | 11 |
| β-strand | 208-211 | 4 | 9 |
| α-helix | 217-222 | 6 | |
| β-strand | 228-231 | 4 | 9 |
| α-helix | 237-240 | 4 | |
| β-strand | 243 | 1 | 12 |
| β-strand | 245 | 1 | 12 |
| β-strand | 250-253 | 4 | 9 |
| α-helix | 254-264 | 11 | |
| α-helix | 279-282 | 4 | |
| α-helix | 289-293 | 5 | |
| α-helix | 296-299 | 4 | |
| α-helix | 311-314 | 4 | |
| α-helix | 322-328 | 7 | |
| α-helix | 331-362 | 32 | |
Chain d: 5 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 22-28 | 7 | 36 |
| α-helix | 29-32 | 4 | |
| α-helix | 38-40 | 3 | |
| α-helix | 42-56 | 15 | |
| β-strand | 62-64 | 3 | 36 |
| α-helix | 66-72 | 7 | |
| β-strand | 83-92 | 10 | 36 |
| α-helix | 93-94 | 2 | |
| β-strand | 102-108 | 7 | 36 |
Chain D: 19 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-15 | 6 | |
| α-helix | 21-25 | 5 | |
| α-helix | 30-37 | 8 | |
| α-helix | 38-40 | 3 | |
| α-helix | 41-43 | 3 | |
| β-strand | 50-55 | 6 | 18 |
| β-strand | 60-66 | 7 | 18 |
| β-strand | 73-79 | 7 | 18 |
| α-helix | 80-82 | 3 | |
| α-helix | 83-86 | 4 | |
| α-helix | 95-113 | 19 | |
| α-helix | 134-135 | 2 | |
| α-helix | 139-142 | 4 | |
| β-strand | 143 | 1 | 19 |
| β-strand | 145-147 | 3 | 18 |
| α-helix | 158-169 | 12 | |
| β-strand | 172 | 1 | 19 |
| β-strand | 184 | 1 | 20 |
| β-strand | 189 | 1 | 20 |
| α-helix | 192-200 | 9 | |
| α-helix | 202-214 | 13 | |
| α-helix | 217-222 | 6 | |
| α-helix | 224-229 | 6 | |
| α-helix | 235-249 | 15 | |
| α-helix | 255-261 | 7 | |
| α-helix | 268-272 | 5 | |
| α-helix | 273-294 | 22 | |
36 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 60S ribosomal protein L21 | T | protein | 159 | Oryctolagus cuniculus | G1SHQ2 (AlphaFold model) |
| 28S rRNA | 5 | RNA | 4808 | Oryctolagus cuniculus | |
| 60S ribosomal protein L7 | F | protein | 225 | Oryctolagus cuniculus | G1SV32 (AlphaFold model) |
| Ribosomal_L18_c domain-containing protein | D | protein | 293 | Oryctolagus cuniculus | P19949 (AlphaFold model) |
| 60S ribosomal protein L18a | S | protein | 176 | Oryctolagus cuniculus | G1TTY7 (AlphaFold model) |
| 60S ribosomal protein L29 | b | protein | 245 | Oryctolagus cuniculus | G1SGR6 |
| Ribosomal protein L3 | B | protein | 394 | Oryctolagus cuniculus | G1TL06 |
| 60S ribosomal protein L31 | d | protein | 107 | Oryctolagus cuniculus | G1SHG0 |
| 5.8S rRNA | 8 | RNA | 156 | Oryctolagus cuniculus | |
| 60S ribosomal protein L7a | G | protein | 319 | Oryctolagus cuniculus | G1STW0 |
| 60S ribosomal protein L11 | J | protein | 170 | Oryctolagus cuniculus | G1TUB8 |
| 60S ribosomal protein L30 | c | protein | 98 | Oryctolagus cuniculus | G1TDL2 |
35 more molecules are not listed.
Sequence of entity 1 (T), FASTA
>8B6C_1 60S ribosomal protein L21 (chains T)
TNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKT
GRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKE
KGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA
Sequence of entity 2 (5), FASTA
>8B6C_2 28S rRNA (chains 5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGCGGGGCGCGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGC
GGGGUCCGGCCGUGCCGGCGGUCUCGGCGGAUCUUUCCCGCUCCCCGUUCCUCCCGACCC
CUCCACCCGCUCCCCCUCCCCCGCCGGUCUUCUCCCUUCACGGGGGGUGGGUCGGCGGGU
GCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGGGGGCGGGGGACCGCCCCCCGGCCGGCG
ACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACGG
CUGGGAAGGCCCCGGCGGGGAAGGUGGCCCGGGGGGACGCCUCGCCGCCGUCGUCCGCGG
CGGCGGCGGGCGCGACCCCUCCCCGGGUGUUACAGCCCCGCCCCGGCAGCAGCAGCUCGC
CGAAUCCCGGGGCCGAGGGAGCGAGACCUGUGUCGCCGCGCUCUCCCCCCUCCCGGCGCU
CCCCCCCGCGGGGGUCCCCCGCGAGGGGGCUCCCCCCGCGGGGGCGCGCCGGUGUCGCCG
CCCUCGCGGGCGCGGCACGGGGGGGCCGGGCCACCCCUCCCACGGCGCGACCGCUCUCCC
GGCCCCCGCCGCCGCCUCUUCGGGCGUGCGGCGGGGGUGGGGCGGACUGUCCCCAGUGCG
CCCCGGGCGGGUCGCGCCGUCGGGCCCGGGGGAGAAGUGGGCCACGGCGCGUCGCGCGCC
UCCGCGUCCCCCCCUCGCCGUCUCCGGGCGGCGGGGGGGGGUUUCGGCGCGGUGUUCUCG
GCGCGCGCGCGCGAGCGAGCGCACGGGGUCGGCGGCGAUGUCGGCUACCCACCCGACCCG
UCUUGAAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCC
GCCGUGGCGCAAUGAAGGUGAAGGCCGGCGGCGGCUUCCCGCCGUCGCCGGCCGAGGUGG
GAUCCCGAGGCCCUUCCAGUCCGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGC
CGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGG
CAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCGAAUCGG
UCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUC
CAAAGUUUCCCUCAGGAUAGCUGGCGCUCUCGCAACCCCGCAGUUUUAUCCGGUAAAGCG
AAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUA
AGAAGCCCGGCUCGCUGGUGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUU
UUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCC
GACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGAUGGUGGCCAUG
GAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAA
AAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCUGGCAGUCGGCAGAGCGA
GAAAGAGAGUGGAGCGCGCCGCGGGACUCCCCCCGCGGGGGUCCCCGGCCACCCCCCCCC
CGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGC
GCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAAC
GAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUC
AGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGC
CCUCAGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGG
CGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCG
GGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAG
AGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGC
CCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGC
AGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCA
AGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGG
GCGCGAAGCGGGGCUGGGCGCGCGCCGCGGCUGGACGAGGCGCCGCCGCCCCCCCCACGC
CCGGGGCGCCCUCCCCCGGCCGGGUCCGCUCCCUCGCGCGCGCGUGCGCCGUGGCGCGCG
CCGCGCGCGCGGCCGAGCCCCGUCUCCCUCCCCCCCUCUCCCCUCCCGGGGCGGGGUGCG
GGGAGGGGCGGGCGGGGCCGUCGCUCGCCGCGCGUGCGCGUCGCUGCGCGUGCGCCGCGC
GGGGGGUCCGGCGGGCCUCCGGACGGGGGCUCCGGGCACCCGGGCACCCGGGGGGCCGGC
GGCGGCGGCGACUCUGGACGCGAGCCGGGCCCUUCCCGUGGAUCGCCCCAGCUGCGGCGG
GCGUCGCGGCCGCCCUCGGGGAGCCCGGCGGGCGCCGCGUGCGCGCGCGUGCGCGCCCGG
GGUCGGGGGGGUGCGAGGCAGGGGAGGCCCUCUCUCCUCCUCCCCCACCCCGGCGCCGCG
GCGCCGCGCGUGCGCGCGCGGUCUCCCCCCGCCGGGUCCGCCCCCGGGGCCGCGGUUCCG
CGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGG
AAUCCGACUGUUUAAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAU
GUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAA
CGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGAC
GCGCAUGAAUGGAUGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAG
CCAAGGGAACGGGCUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUA
GUCUGGCACGGUGAAGAGACAUGAGAAGGUGUAGAAUAAGUGGGAGGCCCCCGGCGCCCU
CCCGCCCCCGCGAGGGGGCGGGGCGGGGUCCGCCGGCCUUGCGGGCCGCCGGUGAAAUAC
CACUCUCCGAUCGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUC
UCGCUUCUGGCGCCAAGCGCCCGGCCCCGUCGGUCCGCGCGGGCCGGCGGGGGCCGGGCG
CGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCGGUACACCUGUCAAA
CGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCUCCCGUGGAGCAGAA
GGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCGUGAAAGCGGGGCCU
CACGAUCCUUCUGACCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAAAGUUACCACAGGGA
UAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUGAUCCUUCGAUGUCG
GCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGUUCACCCACUAAUAG
GGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAUGU
GUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUUCAGACAUUUGGUGU
AUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGGAUUAUGACUGAACG
CCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCGAAGGAGCCUCGGUU
GGCCUCGGAUAGCCGGUCCCCCGCCGUCCCCGCCGGCGGCCCGCGUCGUGCGUCCGCCUC
GGCGGCGUGCGGCGCGCCCCCCGCCGCGCGUCGGGACCGGGGUCCGGUGCGGAGAGCCCU
UCGUCCCGGGAAACGGGGCGCGGCCGGAAAGGGGGCCGCCCUCUCGCCCGUCACGCACCG
CACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACGACCUGCUUCUGGGUCGGGGU
UUCGUACGUAGCAGAGCAGCUCCCUCGCUGCGAUCUAUUGAAAGUCAGCCCUCGACACAA
GGGUUUGU
Sequence of entity 3 (F), FASTA
>8B6C_3 60S ribosomal protein L7 (chains F)
NFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYV
PAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWG
YPNLKSVNELIYKRGYGKINKKRIALTDNTLIARSLGKYNIICMEDLIHEIYTVGKHFKE
ANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN
Sequence of entity 4 (D), FASTA
>8B6C_4 Ribosomal_L18_c domain-containing protein (chains D)
FVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIIC
QIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQ
VEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPG
YDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKK
AHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAA
Sequence of entity 5 (S), FASTA
>8B6C_5 60S ribosomal protein L18a (chains S)
MKASGTLREYKVVGRCLPTPKCRTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGE
IVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRAR
AHSIQIMKVEEIAASKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF
Sequence of entity 6 (b), FASTA
>8B6C_6 60S ribosomal protein L29 (chains b)
MAKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQAN
NAKAMAARAEAIKALVKPKEVKPTIPKGVSRKLHRLAYIAHPKLGRRARARIARGLRLSR
PQTKAKAKTEPQIKGKVKAQIKAQAQAQIKSKGKGKAQAETKPKAQAETKPKAQAQAKPK
AQAQGKPKAQAQGKPKAQAQAKPKAQAQAKPKAQAQTKPKAQATPAAPVPAQAPPKGAQP
PAKAP
Sequence of entity 7 (B), FASTA
>8B6C_7 Ribosomal protein L3 (chains B)
SHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVD
RPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKN
WHKSKKKAFTKYCKKWQDDAGKRQLDKDFSSMKKYCQVIRVLAHTQMRLLPLRQKKAHLM
EIQVNGGTVAEKLDWARERLEQQVPVSQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLP
RKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKN
NASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALE
KIDLKFIDTTSKFGHGRFQTVEEKKAFMGPLKKD
Sequence of entity 8 (d), FASTA
>8B6C_8 60S ribosomal protein L31 (chains d)
NEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGI
RNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDE
Sequence of entity 9 (8), FASTA
>8B6C_9 5.8S rRNA (chains 8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCU
Sequence of entity 10 (G), FASTA
>8B6C_10 60S ribosomal protein L7a (chains G)
MSSYRLGYCMKEERHNLVLCLWSQSPGILNSKCLWPFTNIHLLVGALPREGAGGAWGGGR
SEQLPTCSTTHHDFTWDKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQR
AILYKRLKVPPAINQFTQVLDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGD
VPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCILKGK
ARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSV
ARIAKLEKAKAKELATKLG
Sequence of entity 11 (J), FASTA
>8B6C_11 60S ribosomal protein L11 (chains J)
KENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVRSFGIRRNEK
IAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFGIQEHIDLGIKYDPSIGIYG
LDFYVVLGRPGFSIADKKRRTGCIGAKHRISKEEAMRWFQQKYDGIILPG
Sequence of entity 12 (c), FASTA
>8B6C_12 60S ribosomal protein L30 (chains c)
SLESINSRLQLVMKSGKYVLGYKQSLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKT
GVHHYSGNNIELGTACGKYYRVCTLSIIDPGDSDIIRS
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| MG | Magnesium ion | Mg | 178 |
| ZN | Zinc ion | Zn | 5 |
| OWI | 4-[[9-(cyclohexylmethyl)-3-methylidene-5-(4-methylphenyl)sulfonyl-1,5,9-triazac… | C32 H48 N4 O4 S2 | 1 |
Primary citation
Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative. Pauwels, E., Shewakramani, N.R., De Wijngaert, B. et al. Sci Adv (2023) 9:eadf0797-eadf0797. DOI 10.1126/sciadv.adf0797 · PubMed
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- 7OYD 2.3 Å, Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b
- 11IQ 2.4 Å, Rabbit 80S with eEF2,eIF5A and SERBP1
- 7O7Z 2.4 Å, Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a…
- 8SCB 2.5 Å, Terminating ribosome with SRI-41315
- 9MR4 2.65 Å, NAC: Ribosome nascent chain complex(Oxa1L)
- 9RHU 2.65 Å, Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A…
- 8RJB 2.69 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8VVQ 2.7 Å, Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from…
- 8RJD 2.79 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 6SGC 2.8 Å, Rabbit 80S ribosome stalled on a poly(A) tail
- 7OBR 2.8 Å, RNC-SRP early complex
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