8HT7: PDB entry 8HT7

The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex. Determined by solution NMR. Released 27 Dec 2023.

Method
Solution NMR
Organism
Homo sapiens
Chains
2
Atoms
568
Mol. weight
8.43 kDa
Released
27 Dec 2023

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Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
DNA (5'-d(*gp*gp*gp*tp*tp*ap*gp*gp*gp*tp*tp*ap*gp*gp*gp*tp*tp*tp*gp*gp*g)-3')ADNA21Homo sapiens
Gln-ala-gln-ala-thr-ile-ser-phe-pro-lys-arg-lys-leu-ser-trpBprotein15Homo sapiensQ99741 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>8HT7_1 DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*TP*GP*GP*G)-3') (chains A)
GGGTTAGGGTTAGGGTTTGGG
Sequence of entity 2 (B), FASTA
>8HT7_2 GLN-ALA-GLN-ALA-THR-ILE-SER-PHE-PRO-LYS-ARG-LYS-LEU-SER-TRP (chains B)
QAQATISFPKRKLSW

Primary citation

The N-terminal region of Cdc6 specifically recognizes human DNA G-quadruplex. Geng, Y., Liu, C., Xu, N. et al. Int J Biol Macromol (2024) 260:129487-129487. DOI 10.1016/j.ijbiomac.2024.129487 · PubMed

Other PDB entries of the same protein (UniProt Q99741 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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