8I7R: Meiosis-specific nuclear structural protein 1
In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat. Determined by electron microscopy at 6.5 Å resolution. Released 11 Oct 2023.
- Method
- Electron microscopy
- Resolution
- 6.5 Å
- Organism
- Mus musculus
- Chains
- 450
- Atoms
- 1,283,344
- Mol. weight
- 21412.3 kDa
- Ligands
- GTP
- Released
- 11 Oct 2023
Explore 8I7R in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8I7R contains 6,931 α-helices and 5,011 β-strands across 450 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-88 | 77 | |
Chain A: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 16-117 | 102 | |
| α-helix | 120-328 | 209 | |
Chain A1: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 67-104 | 38 | |
| α-helix | 106-120 | 15 | |
| α-helix | 131-184 | 54 | |
| α-helix | 214-305 | 92 | |
| α-helix | 307-319 | 13 | |
| α-helix | 332-394 | 63 | |
Chain A2: 8 helices, 2 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-104 | 92 | |
| α-helix | 106-120 | 15 | |
| β-strand | 123 | 1 | 82 |
| β-strand | 126 | 1 | 82 |
| α-helix | 131-189 | 59 | |
| α-helix | 214-305 | 92 | |
| α-helix | 308-319 | 12 | |
| α-helix | 332-385 | 54 | |
| α-helix | 386-390 | 5 | |
| α-helix | 391-395 | 5 | |
Chain A3: 6 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-104 | 92 | |
| α-helix | 106-120 | 15 | |
| α-helix | 131-189 | 59 | |
| α-helix | 214-305 | 92 | |
| α-helix | 308-319 | 12 | |
| α-helix | 332-394 | 63 | |
Chain A4: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-98 | 86 | |
| α-helix | 152-190 | 39 | |
| α-helix | 214-245 | 32 | |
Chain AB: 18 helices, 17 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 2-8 | 7 | 198 |
| α-helix | 10-28 | 19 | |
| β-strand | 30 | 1 | 199 |
| β-strand | 35 | 1 | 200 |
| β-strand | 36 | 1 | 199 |
| α-helix | 41-45 | 5 | |
| β-strand | 51-54 | 4 | 200 |
| β-strand | 58-61 | 4 | 200 |
| β-strand | 63-67 | 5 | 198 |
| α-helix | 70-77 | 8 | |
| β-strand | 90-92 | 3 | 198 |
| α-helix | 101-102 | 2 | |
| α-helix | 103-107 | 5 | |
| α-helix | 108-126 | 19 | |
| β-strand | 129-136 | 8 | 198 |
| α-helix | 142-158 | 17 | |
| β-strand | 163-170 | 8 | 198 |
| α-helix | 171-172 | 2 | |
| α-helix | 181-195 | 15 | |
| β-strand | 199-203 | 5 | 198 |
| α-helix | 204-210 | 7 | |
| α-helix | 211-215 | 5 | |
| α-helix | 222-241 | 20 | |
| α-helix | 250-257 | 8 | |
| β-strand | 265-266 | 2 | 198 |
| β-strand | 267-270 | 4 | 201 |
| α-helix | 286-293 | 8 | |
| β-strand | 310-318 | 9 | 201 |
| α-helix | 323-336 | 14 | |
| β-strand | 341 | 1 | 201 |
| β-strand | 349-354 | 6 | 201 |
| β-strand | 364-371 | 8 | 201 |
| α-helix | 375-391 | 17 | |
| α-helix | 396-401 | 6 | |
| α-helix | 405-426 | 22 | |
Chain AC: 22 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4-9 | 6 | 228 |
| α-helix | 11-27 | 17 | |
| β-strand | 53-55 | 3 | 229 |
| β-strand | 61-63 | 3 | 229 |
| β-strand | 65-68 | 4 | 228 |
| α-helix | 72-79 | 8 | |
| α-helix | 89-91 | 3 | |
| β-strand | 92-93 | 2 | 228 |
| α-helix | 103-104 | 2 | |
| α-helix | 105-109 | 5 | |
| α-helix | 111-128 | 18 | |
| β-strand | 134-140 | 7 | 228 |
| α-helix | 146-160 | 15 | |
| β-strand | 165-171 | 7 | 228 |
| α-helix | 172-174 | 3 | |
| α-helix | 183-194 | 12 | |
| β-strand | 200-204 | 5 | 228 |
| α-helix | 206-213 | 8 | |
| α-helix | 224-243 | 20 | |
| β-strand | 248 | 1 | 230 |
| α-helix | 252-259 | 8 | |
| β-strand | 269-272 | 4 | 230 |
| α-helix | 278-282 | 5 | |
| α-helix | 288-295 | 8 | |
| α-helix | 298-300 | 3 | |
| α-helix | 307-309 | 3 | |
| β-strand | 312-321 | 10 | 230 |
| α-helix | 325-337 | 13 | |
| β-strand | 343 | 1 | 230 |
| β-strand | 351-356 | 6 | 230 |
| α-helix | 359-362 | 4 | |
| β-strand | 373-381 | 9 | 230 |
| α-helix | 382-384 | 3 | |
| α-helix | 385-400 | 16 | |
| α-helix | 405-410 | 6 | |
| α-helix | 415-436 | 22 | |
432 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Meiosis-specific nuclear structural protein 1 | A, B | protein | 491 | Mus musculus | Q61884 (AlphaFold model) |
| Tektin-1 | A1, A2, A3, A4 | protein | 418 | Mus musculus | Q9DAJ2 (AlphaFold model) |
| Tubulin beta-4B chain | AB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, EB, ED, EF, EH, EJ, EL, FB, FD, FF, FH, FJ, FL, GB, GD, GF, GH, GJ, GL, HB, HD, HF, HH, HJ, HL, IB, ID, IF, IH, IJ, IL, JB, JD, JF, JH, JJ, JL, KB, KD, KF, KH, KJ, KL, LB, LD, LF, LH, LJ, LL, MB, MD, MF, MH, MJ, ML, NB, ND, NF, NH, NJ, NL, OB, OD, OF, OH, OJ, OL, PB, PD, PF, PH, PJ, PL, QB, QD, QF, QH, QJ, QL, RB, RD, RF, RH, RJ, RL, SB, SD, SF, SH, SJ, SL, TB, TD, TF, TH, TJ, TL, TN, UB, UD, UF, UH, UJ, UL, VB, VD, VF, VH, VJ, VL, WB, WD, WF, WH, WJ, WL | protein | 427 | Mus musculus | P68372 (AlphaFold model) |
| Detyrosinated tubulin alpha-3 chain | AC, AE, AG, AI, AK, AM, BC, BE, BG, BI, BK, BM, CC, CE, CG, CI, CK, CM, DA, DC, DE, DG, DI, DK, EA, EC, EE, EG, EI, EK, FA, FC, FE, FG, FI, FK, GA, GC, GE, GG, GI, GK, HA, HC, HE, HG, HI, HK, IA, IC, IE, IG, II, IK, IM, JA, JC, JE, JG, JI, JK, KA, KC, KE, KG, KI, KK, LA, LC, LE, LG, LI, LK, MC, ME, MG, MI, MK, MM, NA, NC, NE, NG, NI, NK, OA, OC, OE, OG, OI, OK, PA, PC, PE, PG, PI, PK, PM, QC, QE, QG, QI, QK, QM, RC, RE, RG, RI, RK, RM, SC, SE, SG, SI, SK, SM, TC, TE, TG, TI, TK, TM, UA, UC, UE, UG, UI, UK, VA, VC, VE, VG, VI, VK, WA, WC, WE, WG, WI, WK | protein | 438 | Mus musculus | P05214 (AlphaFold model) |
| Tektin-2 | B1, B2, B3, B4, B5, B6, B7, B8, B9 | protein | 430 | Mus musculus | Q922G7 |
| Nucleoside diphosphate kinase 7 | C, D | protein | 395 | Mus musculus | Q9QXL8 |
| Tektin-3 | C1, C2, C3, C4, C5, C6, C7, C8, C9, Ca, Cb, Cc, Cd | protein | 490 | Mus musculus | Q6X6Z7 |
| Tektin-4 | D1, D2, D3, D4, D5, D6, D7, D8, D9, Da | protein | 447 | Mus musculus | Q149S1 |
| EF-hand domain-containing family member B | E, F | protein | 853 | Mus musculus | Q8CDU5 |
| Tektin bundle-interacting protein 1 | E1, E2, E3, E4 | protein | 206 | Mus musculus | A6H6Q4 |
| Tektin-5 | F1, F2, F3, F4, F5, F6, F7, F8, F9, Fa, Fb, Fc, Fd, Fe, Ff, Fg, Fh, Fi, Fj, Fk, Fl, Fm | protein | 557 | Mus musculus | G5E8A8 |
| Cilia- and flagella-associated protein 53 | G, H | protein | 514 | Mus musculus | Q9D439 |
26 more molecules are not listed.
Sequence of entity 1 (A, B), FASTA
>8I7R_1 Meiosis-specific nuclear structural protein 1 (chains A, B)
MATKKRALSFSEKHQKLVDEKFRKSLNIQVMNKLERQAKNQVVQNENDEKVERQRFLRVL
QNEQFELDMEEAIQKAEANKMLRDRQLEQEERLANELARLKHESLKDKKMRQQVRENSIE
LRELEQKLKAAYMNKERAAQIVEKDAMKYEQMKRDAEIERIMMEEHDRLLKEESAKQERR
NKERAQYYLDLEKQLEDQERRKQEAYEQLLKEKLMIDEIVRKIYEEDQVERQQKLEKKNA
IQKYIEEFQRAQDFWRQKKREEMEEENRKIIEFANIQEQREGERMARVHEIEEKRVQRQN
LLMKQLEETLRQRDDLEQVRQELYQEEQAEIIKLKVKEEAELRLRRQREMKQDFEDQMAL
KELILQAAKEEEETFKKAMLAKFAEDDRIELMNAQKQRMKQLEHKRAVEKLIEERRSQFL
ADKQRELEELQLQQRRQGCINEIIEEERLRLLKEHAAKLLGYLPKGVFKREDDVDMLGEE
FRKAYQKRDGV
Sequence of entity 2 (A1, A2, A3, A4), FASTA
>8I7R_2 Tektin-1 (chains A1, A2, A3, A4)
MAKLLQSPPRFLPEEWYIANKSQYHRAEAQRSQSERLVAESQRLVEEIEKTTRKSQSDVN
KKLEQRLEEVRFWKKELDDKLEQLVNQTDDLLTYKTRLERSLESYKEPLHITEKCLEYRE
KRVGIDLVHDVVEQELQKEADIIHGVMNLLIRTLEESTEQIRLNRSAKYNLEKDLRDKFT
AITIDDVCFSLNNNSPNINFSEKVVRIEPNSVSLEDWLDFSNANVEKADKQLNNSTALKT
LVDQILSQTANDLRRQCEVVDEAFINGLKETKDARNKLADHLAKVMEEIASQEKNIMALE
NAITQQEGPAKVAHTRLETRTHRPNVELCRDIAQYRLIKEIQEINHNVARLKETLAQAQT
QLKALYRRQLALQEEIQVKENTIYIDQVLCMEMRKSIPPRDGDDHGAWEGGIRAEAIC
Sequence of entity 3 (AB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, EB, ED, EF, EH, EJ, EL, FB, FD, FF, FH, FJ, FL, GB, GD, GF, GH, GJ, GL, HB, HD, HF, HH, HJ, HL, IB, ID, IF, IH, IJ, IL, JB, JD, JF, JH, JJ, JL, KB, KD, KF, KH, KJ, KL, LB, LD, LF, LH, LJ, LL, MB, MD, MF, MH, MJ, ML, NB, ND, NF, NH, NJ, NL, OB, OD, OF, OH, OJ, OL, PB, PD, PF, PH, PJ, PL, QB, QD, QF, QH, QJ, QL, RB, RD, RF, RH, RJ, RL, SB, SD, SF, SH, SJ, SL, TB, TD, TF, TH, TJ, TL, TN, UB, UD, UF, UH, UJ, UL, VB, VD, VF, VH, VJ, VL, WB, WD, WF, WH, WJ, WL), FASTA
>8I7R_3 Tubulin beta-4B chain (chains AB, AD, AF, AH, AJ, AL, BB, BD, BF, BH, BJ, BL, CB, CD, CF, CH, CJ, CL, DB, DD, DF, DH, DJ, DL, EB, ED, EF, EH, EJ, EL, FB, FD, FF, FH, FJ, FL, GB, GD, GF, GH, GJ, GL, HB, HD, HF, HH, HJ, HL, IB, ID, IF, IH, IJ, IL, JB, JD, JF, JH, JJ, JL, KB, KD, KF, KH, KJ, KL, LB, LD, LF, LH, LJ, LL, MB, MD, MF, MH, MJ, ML, NB, ND, NF, NH, NJ, NL, OB, OD, OF, OH, OJ, OL, PB, PD, PF, PH, PJ, PL, QB, QD, QF, QH, QJ, QL, RB, RD, RF, RH, RJ, RL, SB, SD, SF, SH, SJ, SL, TB, TD, TF, TH, TJ, TL, TN, UB, UD, UF, UH, UJ, UL, VB, VD, VF, VH, VJ, VL, WB, WD, WF, WH, WJ, WL)
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV
PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM
AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQD
Sequence of entity 4 (AC, AE, AG, AI, AK, AM, BC, BE, BG, BI, BK, BM, CC, CE, CG, CI, CK, CM, DA, DC, DE, DG, DI, DK, EA, EC, EE, EG, EI, EK, FA, FC, FE, FG, FI, FK, GA, GC, GE, GG, GI, GK, HA, HC, HE, HG, HI, HK, IA, IC, IE, IG, II, IK, IM, JA, JC, JE, JG, JI, JK, KA, KC, KE, KG, KI, KK, LA, LC, LE, LG, LI, LK, MC, ME, MG, MI, MK, MM, NA, NC, NE, NG, NI, NK, OA, OC, OE, OG, OI, OK, PA, PC, PE, PG, PI, PK, PM, QC, QE, QG, QI, QK, QM, RC, RE, RG, RI, RK, RM, SC, SE, SG, SI, SK, SM, TC, TE, TG, TI, TK, TM, UA, UC, UE, UG, UI, UK, VA, VC, VE, VG, VI, VK, WA, WC, WE, WG, WI, WK), FASTA
>8I7R_4 Detyrosinated tubulin alpha-3 chain (chains AC, AE, AG, AI, AK, AM, BC, BE, BG, BI, BK, BM, CC, CE, CG, CI, CK, CM, DA, DC, DE, DG, DI, DK, EA, EC, EE, EG, EI, EK, FA, FC, FE, FG, FI, FK, GA, GC, GE, GG, GI, GK, HA, HC, HE, HG, HI, HK, IA, IC, IE, IG, II, IK, IM, JA, JC, JE, JG, JI, JK, KA, KC, KE, KG, KI, KK, LA, LC, LE, LG, LI, LK, MC, ME, MG, MI, MK, MM, NA, NC, NE, NG, NI, NK, OA, OC, OE, OG, OI, OK, PA, PC, PE, PG, PI, PK, PM, QC, QE, QG, QI, QK, QM, RC, RE, RG, RI, RK, RM, SC, SE, SG, SI, SK, SM, TC, TE, TG, TI, TK, TM, UA, UC, UE, UG, UI, UK, VA, VC, VE, VG, VI, VK, WA, WC, WE, WG, WI, WK)
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDLAALEKDYEEVGVD
Sequence of entity 5 (B1, B2, B3, B4, B5, B6, B7, B8, B9), FASTA
>8I7R_5 Tektin-2 (chains B1, B2, B3, B4, B5, B6, B7, B8, B9)
MATLSFKPSERYRLSDWRTNSYLLSTNAERQRDASHQIRQEARILRNETNNQIVWDEHDN
RTRLAERIDTVNRWKETLDKCLTDLDAEIDSLAQAKESAEQNLQAKNLPLDVAIECLTLR
ESRRDIDVVRDPVEEELLKEVEVIEATKKVLQEKISQAFQHLCLLQEIRQQLNSDHRDKM
ETLEIDRGCLSLNLTSPNISLKVNPTRIPKDSTTLQQWDEFTRFNKNRAEAEMKASIELR
EAIALAIAQTNNELDAQRVATEFTFRKRLREMESFYSELKWQEKNTLEEIAELQGDIRRL
EEDLRRKMMNLKLAHTRLESRTYRSNVELCRDQTQYGLIDEVHQLEATINTMKQKLAQTQ
NALDALFKHLARIQADIACKTNTLLLDTKCMDTRRKLTVPAEKFVPQVDTFTRTTNRTLS
PLKICQLELT
Sequence of entity 6 (C, D), FASTA
>8I7R_6 Nucleoside diphosphate kinase 7 (chains C, D)
MRACQQGRSSSLVSPYMAPKNQSERFAFIAEWYDPNASLLRRYELLFYPVDGSVEMHDVK
NRRTFLKRTKYEDLRLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPD
AVSKAGEIIEMINKSGFTITKLRMMTLTRKEAADFHVDHHSRPFYNELIQFITSGPVIAM
EILRDDAICEWKRLLGPANSGLSRTDAPGSIRALFGTDGVRNAAHGPDTFASAAREMELF
FPSSGGCGPANTAKFTNCTCCIIKPHAISEGMLGKNLIAIRDACFGMSAIQMFNLDRANV
EEFYEVYKGVVSEYNDMVTELCSGPCVAIEIQQSNPTKTFREFCGPADPEIARHLRPETL
RAIFGKTKVQNAVHCTDLPEDGLLEVQYFFKILDN
Sequence of entity 7 (C1, C2, C3, C4, C5, C6, C7, C8, C9, Ca, Cb, Cc, Cd), FASTA
>8I7R_7 Tektin-3 (chains C1, C2, C3, C4, C5, C6, C7, C8, C9, Ca, Cb, Cc, Cd)
MELLGSTLTATYAHPPPASASFLPAIGTITSSYKDRFPHRNLTHSLSLPWRPNTYYKTAY
NYPTLAPYSSRSQRVCESTMLPFVSNRTTFFTRYTPDDWYRSNLVSFQESNSSRHNSERL
RVDTSRLIQDKYQQIRKTQAHSTQNLGERVNDLAFWKSEITHELDEMIGETNALTDIKRR
LERGLIETEGPLQVSRECLFHREKRMGIDLVHDEAEKELLAEVDTILCCQERMRQHLDKA
NAQLASDRSAQHELEKDLSDKQAALRIDDKCQHLRNTSEGVSYFRGVERVDATVSVPETW
AKFTDDNVLRSQSERAASAKLREETENLLIVTANEMWNQFNKVNLAFTNRIAETVDAKNK
IHTHLTKTLQEIFQIEMTIESIKKAIKEKSAFLKVAQTRLDERTRRPNVELCRDMAQLRL
VNEVYEVDETIQTLQQRLRDSEDTLQSLAHTKATLEHDLAVKANTLYIDQEKCMSMRNSY
PSTLRLVGYC
Sequence of entity 8 (D1, D2, D3, D4, D5, D6, D7, D8, D9, Da), FASTA
>8I7R_8 Tektin-4 (chains D1, D2, D3, D4, D5, D6, D7, D8, D9, Da)
MAQTGVLLTKEPAPQSIDVCELPRKEYEVACNTGAYTSSGLATAGFRTAKYLRDEWFQNS
YARYHQAFADRDYSERQRHESGQLVAETGALAQRTQLDSTRKVGERLEDMHCWKSELQRE
IDELSSETDLMMAQKLRLQRALDATSVPYSIATDNLQCRERRQHPDLVRDYVEVELLKET
ELIRNIQELLKRTIGQAVDQIRLNREHKESCEMNWSDKVEVYNIDDTCSRYTNESTQVQF
YPHSSKFEESASTPETWAKFNHDNLLRAERERLASVNLRKLIDCILRDTAEDLRLQCDAV
NSAFSSRCQELDDSLQKLQYHLRKTLTEITDQEHQIAALKQAIKDKEAPLRVAQTRLYQR
SHRPNVELCRDNAQFRLLSEVEELNMSLRALKEKLQDAEQALRNLEDSRMSLEKDIAVKT
NSLFIDRQKCMTHRNRYPSVLQLAGYQ
Sequence of entity 9 (E, F), FASTA
>8I7R_9 EF-hand domain-containing family member B (chains E, F)
MCSFVRVGSPKPLQTSASPLEMSSLRRTRAPEISELGLTPEQKDDIRDRVLRGSKSPTEL
GFDLRLEQDRKWRERMGSSEAKSPPCHALGVGLERHTISGTPTEMGNLGLHKGSAFQGSK
PLGVLPGRVGPENKGLPPRLRYGGTLHPPFSTVHASPLAAESRRRPLAWGSAWTDAVVEK
QPVVGLELRKEPEKEPTCVVMNPYPEMPPKEVDIGLPQTQESDEAKNTEPLIGLVREPSE
CPFAQQPEEKKEPGSTEPGVEPPGNIRPIYSGKFFDRVPCWPSAGKVKPVGYRVATCLTE
KLPRLMTPPEAKKYFNFRYPPAGAERVFYGRANDPQIAPYLTHGLRSKISIPMGSLINPQ
PITTFQQKIKDKKESIYFSHQRAPLGKSHDQTPGLPKGMDVINTTLGTPTIRELSVRDTV
NPSKSFEDVLKEGQEGHDLYTVSHNDYFAGEAKNRKYNPASFHRFNLYGIPTPHFNDGRT
MAKALHWLHELQMERGAKIVSKRVDDFKEKFQHKLGKVLDPIAETMNVPPGHTFGSCLHP
EEYGAGDLIHYRSPDEYLRGKDHQRAVVAAARHHLKKFNHQNFDTLQVAFRHYDKKGDGV
IDRAELHEACVQANLHLDKMLLDHLFDYCDVDQDGLINYLEFANFLNWKDRIPLKEHEKR
VVVKGKKPDCENVTDTSMGEAEPSLLINPEDIVPKEPGSSEETLRTIQRPGDKVSHQYKT
TSSEINAVVGAVPSMCHPIFGVPTIRSDISAPRIRRVSDMNNYGDEGNAYSLLHPSIFSQ
KGVFERDFFKTRSKEEISDILTNIGVKLSKEEFENVWNLASKKHQRGEVCVETIRNVLDE
LLHADLVKCKTAM
Sequence of entity 10 (E1, E2, E3, E4), FASTA
>8I7R_10 Tektin bundle-interacting protein 1 (chains E1, E2, E3, E4)
MENVRREATRPSVPSGTLELYFPDHLYRNDYVSLEGPRWAPAIKQAVRWKFTPMGRDAAG
QVWFTGLTNSEPGDAWYKLPRALDTPYREAHTRWHGCFQSRQRGLPPAYTQHLREMAFWD
PAITAQYLNSGPRWGCMQWRDRQIRGKEFVVTRNQFGAKLPWRSDYVPLLSLPQRPRFTA
QDFRQRGLQRPCPAIGQPPPAFTPAL
Sequence of entity 11 (F1, F2, F3, F4, F5, F6, F7, F8, F9, Fa, Fb, Fc, Fd, Fe, Ff, Fg, Fh, Fi, Fj, Fk, Fl, Fm), FASTA
>8I7R_11 Tektin-5 (chains F1, F2, F3, F4, F5, F6, F7, F8, F9, Fa, Fb, Fc, Fd, Fe, Ff, Fg, Fh, Fi, Fj, Fk, Fl, Fm)
MEFLGTTQTASFCGPKKGCGLQALPPAGQEPVVQECYQPFHLPGYRYLNAWRPSVFHKIA
TSQTIPEECSGIRRPPTILPSLRSALFCRYTPRDWDRSNDLQIRNAEASRLWASRLTGDS
LRIMQDKDQLIHQMQEGTSRNLGQRLSDLGFWKSELCYELDRLLTENSSMDTLKRRLECA
AEEVNCPLQVALECLYNREKRIGIDLVHDNVEKNLIREVDLLKCCQDQMRKLAKRIDFQI
RDNRDAQHSLERDIEDKSSAQYIDENCFNLRSTSDSISFFHGVEKFDGTVSIPETWAKFS
NDNIRHAQNMRANSIRLREEAEHLFETLSDQMWKQFTNTNLAFNARISEETDVKNKLQTQ
LAKILQEIFQAENTIMLLERAIVAKEYPLKMAQTMLACRTRRPNVELCRDVPQFRLVNEV
FTIDDTLQTLKLRLRETQDTLQLLVMTKSRLEHELAIKANTLCIDKDKCMSMRKSFPSTP
RLTGYTCSAIGSGPYANHAPRISSGPCSGSALCKGPASCGGGASCGGGASCGGHAPCGSA
LCSHSVSRSGPGFAPVC
Sequence of entity 12 (G, H), FASTA
>8I7R_12 Cilia- and flagella-associated protein 53 (chains G, H)
MYSQQFGTVPREFKGPTPKAVIIRAKPPKAQRAEQHLKRIQRSYHKYHTTLASIKSNEEN
RLKCDWIQRNNHKTFDSLVQARVQDAMQGFVINTEERRNKLRELLASEENEYFSEMQLKG
ETIEEKKDKMRERTKLLREKKEKERQEFVAEKLDQQFRERCEELRTKLASIHEKKVVEER
NAQIEFNKELKRQKLVEEHLFARLWEEDRLAKERREAQEEKRQRELVQNTRLGLDAQVTS
IQAQRQGARRMKEEEARILEQNKAQIKREDEQEKLQKQKRRQETRSSLKKAVQDKIESMQ
REYREDLDLNMKLVGRALQDLQDEADKKKQKREEMGREQKIYNDYLMQRREEEKAQEKEL
NRLLEDIKAKKLAEKDRELALQRAARKQLMNEVMNTRKLQVQERLQRKLREQEELALHEQ
RISESLKVLHQEDMEDFARRCALAEEYRNQLQMQIAHQQQAREAEKEEERQEFEAGLAAN
KACLDKIQRILSENQALSQNVHPMRRGYPDKPPL
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 279 |
Primary citation
In-cell structural insight into the stability of sperm microtubule doublet. Tai, L., Yin, G., Huang, X. et al. Cell Discov (2023) 9:116-116. DOI 10.1038/s41421-023-00606-3 · PubMed
Other PDB entries of the same protein (UniProt Q61884 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8IYJ 3.5 Å, Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
- 9V10 3.7 Å, Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
- 8TO0 7.7 Å, 48-nm repeating structure of doublets from mouse sperm flagella
Browse structure collections
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