8PR3: Cytoplasmic dynein-1 heavy chain
Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1. Determined by electron microscopy at 3.9 Å resolution. Released 27 Mar 2024.
- Method
- Electron microscopy
- Resolution
- 3.9 Å
- Organism
- Homo sapiens
- Chains
- 9
- Atoms
- 17,888
- Mol. weight
- 1497.46 kDa
- Released
- 27 Mar 2024
Explore 8PR3 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8PR3 contains 78 α-helices and 82 β-strands across 9 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain B: 2 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 27-46 | 20 | |
| α-helix | 56-127 | 72 | |
Chain C: 3 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 24-26 | 3 | |
| α-helix | 27-46 | 20 | |
| α-helix | 56-127 | 72 | |
Chains E and F: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 430-438 | 9 | |
Chain f: 23 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 561-571 | 11 | |
| α-helix | 578-585 | 8 | |
| α-helix | 589-591 | 3 | |
| α-helix | 597-603 | 7 | |
| α-helix | 605-624 | 20 | |
| α-helix | 631-636 | 6 | |
| α-helix | 643-669 | 27 | |
| α-helix | 677-690 | 14 | |
| α-helix | 691-693 | 3 | |
| α-helix | 696-709 | 14 | |
| β-strand | 716 | 1 | 1 |
| β-strand | 718-723 | 6 | 2 |
| β-strand | 732-737 | 6 | 2 |
| α-helix | 741-753 | 13 | |
| α-helix | 762-772 | 11 | |
| α-helix | 775-797 | 23 | |
| α-helix | 799-805 | 7 | |
| α-helix | 806-819 | 14 | |
| β-strand | 823 | 1 | 1 |
| α-helix | 829-862 | 34 | |
| α-helix | 871-890 | 20 | |
| α-helix | 896-922 | 27 | |
| α-helix | 986-994 | 9 | |
| α-helix | 996 | 1 | |
| β-strand | 997 | 1 | 3 |
| α-helix | 998-1000 | 3 | |
| α-helix | 1014-1017 | 4 | |
| β-strand | 1018 | 1 | 3 |
| α-helix | 1031-1038 | 8 | |
Chain h: 5 helices, 30 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 239-245 | 7 | 4 |
| β-strand | 256-261 | 6 | 5 |
| β-strand | 268-273 | 6 | 5 |
| β-strand | 285-291 | 7 | 5 |
| β-strand | 301-305 | 5 | 5 |
| β-strand | 309-314 | 6 | 6 |
| β-strand | 321-326 | 6 | 6 |
| β-strand | 331-335 | 5 | 6 |
| β-strand | 345 | 1 | 6 |
| α-helix | 357 | 1 | |
| β-strand | 358-365 | 8 | 7 |
| β-strand | 370-376 | 7 | 7 |
| β-strand | 380-384 | 5 | 7 |
| β-strand | 394-397 | 4 | 7 |
| β-strand | 399 | 1 | 8 |
| β-strand | 405 | 1 | 8 |
| β-strand | 408-412 | 5 | 9 |
| β-strand | 420-425 | 6 | 9 |
| β-strand | 430-434 | 5 | 9 |
| β-strand | 441-446 | 6 | 9 |
| β-strand | 453-458 | 6 | 10 |
| β-strand | 470-475 | 6 | 10 |
| β-strand | 480-484 | 5 | 10 |
| β-strand | 492-494 | 3 | 10 |
| β-strand | 501-506 | 6 | 11 |
| β-strand | 513-518 | 6 | 11 |
| β-strand | 522-527 | 6 | 11 |
| β-strand | 537-540 | 4 | 11 |
| β-strand | 550-552 | 3 | 4 |
| β-strand | 558-561 | 4 | 4 |
| β-strand | 568-573 | 6 | 4 |
| α-helix | 574 | 1 | |
| α-helix | 575-578 | 4 | |
| α-helix | 580-581 | 2 | |
| α-helix | 584-607 | 24 | |
Chain j: 15 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 50-52 | 3 | |
| β-strand | 56-60 | 5 | 12 |
| α-helix | 67-75 | 9 | |
| β-strand | 86-94 | 9 | 12 |
| β-strand | 101-109 | 9 | 12 |
| α-helix | 113-118 | 6 | |
| α-helix | 119-122 | 4 | |
| β-strand | 131-138 | 8 | 12 |
| α-helix | 142-144 | 3 | |
| α-helix | 145-160 | 16 | |
| α-helix | 169-182 | 14 | |
| β-strand | 227-232 | 6 | 12 |
| α-helix | 234-237 | 4 | |
| α-helix | 238-242 | 5 | |
| α-helix | 248-265 | 18 | |
| β-strand | 269-271 | 3 | 12 |
| β-strand | 273 | 1 | 13 |
| β-strand | 278 | 1 | 13 |
| α-helix | 280-292 | 13 | |
| β-strand | 301 | 1 | 12 |
| β-strand | 309-310 | 2 | 12 |
| α-helix | 321-324 | 4 | |
| α-helix | 342-344 | 3 | |
| α-helix | 356-358 | 3 | |
| α-helix | 359-372 | 14 | |
Chain m: 25 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 271-286 | 16 | |
| α-helix | 323-336 | 14 | |
| α-helix | 341-346 | 6 | |
| α-helix | 350-363 | 14 | |
| α-helix | 374-399 | 26 | |
| α-helix | 401-403 | 3 | |
| α-helix | 406-438 | 33 | |
| α-helix | 457-483 | 27 | |
| α-helix | 514-531 | 18 | |
| α-helix | 540-568 | 29 | |
| α-helix | 571-574 | 4 | |
| α-helix | 578-587 | 10 | |
| α-helix | 589-593 | 5 | |
| α-helix | 595-600 | 6 | |
| α-helix | 603-622 | 20 | |
| α-helix | 631-637 | 7 | |
| α-helix | 643-669 | 27 | |
| α-helix | 673-675 | 3 | |
| α-helix | 679-692 | 14 | |
| α-helix | 696-709 | 14 | |
| β-strand | 716 | 1 | 14 |
| β-strand | 719 | 1 | 15 |
| β-strand | 736 | 1 | 15 |
| α-helix | 743-753 | 11 | |
| α-helix | 762-797 | 36 | |
| α-helix | 799-801 | 3 | |
| α-helix | 806-820 | 15 | |
| β-strand | 823 | 1 | 14 |
| α-helix | 829-853 | 25 | |
Chain o: 3 helices, 32 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 239-245 | 7 | 16 |
| β-strand | 256-261 | 6 | 17 |
| β-strand | 268-273 | 6 | 17 |
| β-strand | 285-291 | 7 | 17 |
| β-strand | 301-305 | 5 | 17 |
| β-strand | 309-314 | 6 | 18 |
| β-strand | 321-326 | 6 | 18 |
| β-strand | 331-335 | 5 | 18 |
| β-strand | 345 | 1 | 18 |
| β-strand | 358-365 | 8 | 19 |
| β-strand | 370-376 | 7 | 19 |
| β-strand | 380-384 | 5 | 19 |
| β-strand | 385 | 1 | 20 |
| β-strand | 388 | 1 | 20 |
| β-strand | 395-397 | 3 | 19 |
| β-strand | 399-400 | 2 | 21 |
| β-strand | 404-405 | 2 | 21 |
| α-helix | 406 | 1 | |
| β-strand | 411-412 | 2 | 22 |
| β-strand | 420-423 | 4 | 22 |
| β-strand | 430-434 | 5 | 22 |
| β-strand | 441-446 | 6 | 22 |
| β-strand | 453-458 | 6 | 23 |
| β-strand | 470-475 | 6 | 23 |
| β-strand | 480-484 | 5 | 23 |
| β-strand | 492-494 | 3 | 23 |
| β-strand | 501-506 | 6 | 24 |
| β-strand | 513-518 | 6 | 24 |
| β-strand | 522-527 | 6 | 24 |
| β-strand | 537-540 | 4 | 24 |
| β-strand | 547-552 | 6 | 16 |
| β-strand | 558-563 | 6 | 16 |
| β-strand | 568-573 | 6 | 16 |
| α-helix | 575-578 | 4 | |
| α-helix | 584-607 | 24 | |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| C-Jun-amino-terminal kinase-interacting protein 3 | B, C | protein | 581 | Homo sapiens | Q9UPT6 (AlphaFold model) |
| Cytoplasmic dynein 1 heavy chain 1 | f, m | protein | 4646 | Homo sapiens | Q14204 |
| Cytoplasmic dynein 1 intermediate chain 2 | h, o | protein | 612 | Homo sapiens | Q13409 (AlphaFold model) |
| Cytoplasmic dynein 1 light intermediate chain 2 | E, F, j | protein | 492 | Homo sapiens | O43237 (AlphaFold model) |
Sequence of entity 1 (B, C), FASTA
>8PR3_1 C-Jun-amino-terminal kinase-interacting protein 3 (chains B, C)
SNIEFLKMMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVK
ELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRRQAEEKFIEFED
ALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQ
TYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKLVPAGDHW
HLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQ
PLGDYGVGSKNSKRAREKRDSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDM
CPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDF
FGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLE
NRIKELEEELKRVKSEAIIARREPKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLM
ERNQYKERLMELQEAVRWTEMIRASREGSGSGRWSHPQFEK
Sequence of entity 2 (f, m), FASTA
>8PR3_2 Cytoplasmic dynein 1 heavy chain 1 (chains f, m)
MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS
ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK
RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP
SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT
FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT
LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI
FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF
QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI
VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK
EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA
IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA
YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI
ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS
LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV
FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV
NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH
ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR
NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ
ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT
EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ
RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD
WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ
VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY
ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ
KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH
INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL
LPVETQEFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGEIQKALGEYLE
RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE
GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT
WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ
PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ
MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG
HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE
ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA
MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA
GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL
LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL
MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF
THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR
IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG
KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS
MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR
ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL
LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE
YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW
VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP
SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG
LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD
YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG
AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL
DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR
NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY
IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI
NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL
KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK
KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS
DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE
DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK
SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN
IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI
MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV
LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE
RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV
TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL
YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT
YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW
LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI
MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA
DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR
AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG
WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF
DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW
LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL
HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG
KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG
AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV
TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF
TVDFEIATKEDPRSFYERGVAVLCTE
Sequence of entity 3 (h, o), FASTA
>8PR3_3 Cytoplasmic dynein 1 intermediate chain 2 (chains h, o)
MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA
EALLQSMGLTPESPIVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRRGPIKLGMAKITQV
DFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEKTLKKDEENDSKAPPH
ELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRDLEDKEGEIQAGAKLS
LNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDGVALVWNMKYKKTTPE
YVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAAAHTHPVYC
VNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKAVAVTSMSFPVGDVNN
FVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAVDFSHLFVTSSFDWTV
KLWSTKNNKPLYSFEDNAGYVYDVMWSPTHPALFACVDGMGRLDLWNLNNDTEVPTASIS
VEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEWARFGRTLAEINANRA
DAEEEAATRIPA
Sequence of entity 4 (E, F, j), FASTA
>8PR3_4 Cytoplasmic dynein 1 light intermediate chain 2 (chains E, F, j)
MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVF
GEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLK
FAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVL
EKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPA
LVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIK
NNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPD
SMVTNSSTENEA
Primary citation
Molecular mechanism of dynein-dynactin complex assembly by LIS1. Singh, K., Lau, C.K., Manigrasso, G. et al. Science (2024) 383:eadk8544-eadk8544. DOI 10.1126/science.adk8544 · PubMed
Other PDB entries of the same protein (UniProt Q9UPT6 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 4PXJ 2.06 Å, Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3
- 8PR4 3.5 Å, Dynactin pointed end bound to JIP3
- 8PR2 3.8 Å, Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI
- 8PTK 10.0 Å, Composite structure of Dynein-Dynactin-JIP3-LIS1
Browse structure collections
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