8PTK: Composite structure of Dynein-Dynactin-JIP3-LIS1

Composite structure of Dynein-Dynactin-JIP3-LIS1. Determined by electron microscopy at 10.0 Å resolution. Released 27 Mar 2024.

Method: Electron microscopy
Resolution: 10.0 Å
Organisms: Homo sapiens, Sus scrofa
Chains: 53
Atoms: 161,538
Mol. weight: 4180.97 kDa
Ligands: ANP, MG, ZN, ATP
Released: 27 Mar 2024

Explore 8PTK in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8PTK contains 1,365 α-helices and 1,056 β-strands across 53 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 1: 7 helices, 32 β-strands

Element	Residues	Length	Sheet
α-helix	5-21	17
α-helix	25-34	10
α-helix	50-56	7
α-helix	58-79	22
α-helix	91-93	3
β-strand	96	1	1
β-strand	102-105	4	2
β-strand	111-116	6	3
β-strand	123-127	5	3
β-strand	132-135	4	3
β-strand	142-146	5	3
β-strand	153-158	6	4
β-strand	164-169	6	4
β-strand	173-178	6	4
β-strand	183-189	7	4
β-strand	195	1	5
β-strand	199-200	2	6
β-strand	206-210	5	6
β-strand	211	1	5
β-strand	215-220	6	6
β-strand	226-231	6	6
β-strand	237-242	6	7
β-strand	248-253	6	7
β-strand	258-262	5	7
β-strand	268-272	5	7
β-strand	281-284	4	8
α-helix	285-286	2
α-helix	287-296	10
β-strand	310-314	5	8
β-strand	319-324	6	8
β-strand	329-335	7	8
β-strand	341-346	6	9
β-strand	352-357	6	9
β-strand	362-366	5	9
β-strand	371-376	6	9
β-strand	383-388	6	2
β-strand	394-399	6	2
β-strand	403-408	6	2
β-strand	409	1	1

Chain 2: 8 helices, 30 β-strands

Element	Residues	Length	Sheet
α-helix	5-20	16
α-helix	25-35	11
α-helix	41-44	4
α-helix	50-79	30
α-helix	91-93	3
β-strand	96	1	12
β-strand	102-105	4	13
β-strand	111-116	6	14
β-strand	123-127	5	14
β-strand	132-136	5	14
β-strand	141-146	6	14
β-strand	155-158	4	15
β-strand	164-168	5	15
β-strand	174-178	5	15
β-strand	184-188	5	15
β-strand	195-200	6	16
β-strand	206-211	6	16
β-strand	215-220	6	16
β-strand	226-231	6	16
β-strand	237-242	6	17
β-strand	248-253	6	17
β-strand	258-262	5	17
β-strand	268-272	5	17
β-strand	279-284	6	18
α-helix	285-286	2
α-helix	287-289	3
α-helix	290-297	8
β-strand	310-315	6	18
β-strand	319-324	6	18
β-strand	329-335	7	18
β-strand	341-346	6	19
β-strand	352-357	6	19
β-strand	361-366	6	19
β-strand	371-377	7	19
β-strand	383-388	6	13
β-strand	394-399	6	13
β-strand	403-408	6	13
β-strand	409	1	12

Chain 3: 3 helices, 32 β-strands

Element	Residues	Length	Sheet
α-helix	91-93	3
β-strand	96	1	28
β-strand	102-105	4	29
β-strand	111-116	6	30
β-strand	123-127	5	30
β-strand	132-135	4	30
β-strand	142-146	5	30
β-strand	153-158	6	31
β-strand	164-169	6	31
β-strand	173-178	6	31
β-strand	183-189	7	31
β-strand	195	1	32
β-strand	199-200	2	33
β-strand	206-210	5	33
β-strand	211	1	32
β-strand	215-220	6	33
β-strand	226-231	6	33
β-strand	237-242	6	34
β-strand	248-253	6	34
β-strand	258-262	5	34
β-strand	268-272	5	34
β-strand	279-284	6	35
α-helix	285-286	2
α-helix	288-296	9
β-strand	310-315	6	35
β-strand	319-324	6	35
β-strand	329-335	7	35
β-strand	341-346	6	36
β-strand	352-357	6	36
β-strand	362-366	5	36
β-strand	371-376	6	36
β-strand	383-388	6	29
β-strand	394-399	6	29
β-strand	403-408	6	29
β-strand	409	1	28

Chain 4: 3 helices, 30 β-strands

Element	Residues	Length	Sheet
α-helix	91-93	3
β-strand	96	1	38
β-strand	102-105	4	39
β-strand	111-116	6	40
β-strand	123-127	5	40
β-strand	132-135	4	40
β-strand	142-146	5	40
β-strand	155-158	4	41
β-strand	164-168	5	41
β-strand	173-178	6	41
β-strand	184-189	6	41
β-strand	195-200	6	42
β-strand	206-211	6	42
β-strand	215-220	6	42
β-strand	226-231	6	42
β-strand	237-242	6	43
β-strand	248-253	6	43
β-strand	258-262	5	43
β-strand	268-272	5	43
β-strand	279-284	6	44
α-helix	285-286	2
α-helix	290-297	8
β-strand	310-315	6	44
β-strand	319-324	6	44
β-strand	329-335	7	44
β-strand	341-346	6	45
β-strand	352-357	6	45
β-strand	361-366	6	45
β-strand	371-377	7	45
β-strand	383-388	6	39
β-strand	394-399	6	39
β-strand	403-408	6	39
β-strand	409	1	38

Chain a: 2 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	7-12	6	37
α-helix	15-31	17
α-helix	35-49	15
β-strand	54-68	15	37
β-strand	73-78	6	37
β-strand	81-87	7	37

Chain A: 21 helices, 23 β-strands

Element	Residues	Length	Sheet
α-helix	10-11	2
β-strand	12-15	4	46
β-strand	20-21	2	47
β-strand	22-25	4	46
β-strand	35-36	2	47
β-strand	39-42	4	48
β-strand	45-46	2	49
β-strand	57	1	48
α-helix	60-64	5
β-strand	69-72	4	48
β-strand	75-76	2	50
β-strand	79-80	2	50
α-helix	83-93	11
β-strand	108-112	5	46
α-helix	118-126	9
α-helix	127-131	5
β-strand	137-141	5	46
α-helix	142-149	8
β-strand	155-160	6	51
β-strand	165-171	7	51
β-strand	174-175	2	51
α-helix	176	1
β-strand	181-183	3	51
α-helix	187-200	14
α-helix	211-220	10
β-strand	223	1	52
α-helix	228-232	5
α-helix	235-237	3
β-strand	240-242	3	53
β-strand	248-250	3	53
α-helix	254-257	4
α-helix	258-261	4
α-helix	275-284	10
α-helix	291-296	6
β-strand	298-301	4	51
β-strand	308	1	52
α-helix	310-321	12
α-helix	323	1
β-strand	330-331	2	51
α-helix	339-348	10
α-helix	352-354	3
β-strand	358	1	46
α-helix	360-365	6
α-helix	368-374	7

Chain b: 2 helices, 4 β-strands

Element	Residues	Length	Sheet
β-strand	6-12	7	37
α-helix	15-31	17
α-helix	35-49	15
β-strand	54-68	15	37
β-strand	73-78	6	37
β-strand	81-87	7	37

Chain B: 20 helices, 22 β-strands

Element	Residues	Length	Sheet
α-helix	10-11	2
β-strand	12-16	5	56
β-strand	20-25	6	56
β-strand	33-36	4	56
β-strand	39-42	4	57
β-strand	45-46	2	58
β-strand	57	1	57
α-helix	60-64	5
β-strand	69-72	4	57
β-strand	75-76	2	59
β-strand	79-80	2	59
α-helix	83-93	11
β-strand	108-112	5	56
α-helix	118-126	9
α-helix	127-131	5
β-strand	136-141	6	56
α-helix	142-150	9
β-strand	155-160	6	60
β-strand	165-171	7	60
β-strand	174-175	2	60
β-strand	181-183	3	60
α-helix	187-199	13
α-helix	208-220	13
β-strand	223	1	61
α-helix	228-233	6
α-helix	235-236	2
β-strand	240-242	3	62
β-strand	248-250	3	62
α-helix	254-257	4
α-helix	258-261	4
α-helix	265-268	4
α-helix	275-284	10
α-helix	288-295	8
β-strand	298-301	4	60
β-strand	308	1	61
α-helix	310-321	12
β-strand	329-331	3	60
α-helix	339-348	10
α-helix	353-355	3
β-strand	358-359	2	56
α-helix	360-365	6
α-helix	368-374	7

45 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Platelet-activating factor acetylhydrolase IB subunit beta	1, 2, 3, 4	protein	410	Homo sapiens	P43034 (AlphaFold model)
ARP1 actin related protein 1 homolog A	A, B, C, D, E, F, G, I	protein	376	Sus scrofa	F2Z5G5 (AlphaFold model)
Actin, cytoplasmic 1	H	protein	375	Sus scrofa	Q6QAQ1 (AlphaFold model)
Arp11	J	protein	417	Sus scrofa	I3LHK5 (AlphaFold model)
Capping protein (Actin filament) muscle Z-line, alpha 1	K	protein	286	Sus scrofa	A0PFK5
F-actin-capping protein subunit beta	L	protein	272	Sus scrofa	A0PFK7
Dynactin subunit 2	M, N, P, Q	protein	405	Sus scrofa	A0A5G2QD80
Dynactin subunit 3	O, R	protein	186	Sus scrofa	F1SEC0
Dynactin subunit 1	S, T	protein	1281	Sus scrofa	A0A287B8J2
Dynactin 6	U	protein	190	Sus scrofa	D0G6S1
Dynactin subunit 5	W	protein	182	Sus scrofa	A0A286ZK88
C-Jun-amino-terminal kinase-interacting protein 3	X, x	protein	581	Homo sapiens	Q9UPT6

7 more molecules are not listed.

Sequence of entity 1 (1, 2, 3, 4), FASTA

>8PTK_1 Platelet-activating factor acetylhydrolase IB subunit beta (chains 1, 2, 3, 4)
MVLSQRQRDELNRAIADYLRSNGYEEAYSVFKKEAELDVNEELDKKYAGLLEKKWTSVIR
LQKKVMELESKLNEAKEEFTSGGPLGQKRDPKEWIPRPPEKYALSGHRSPVTRVIFHPVF
SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ
GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMV
RPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSE
TKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDK
TLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVWECR

Sequence of entity 2 (A, B, C, D, E, F, G, I), FASTA

>8PTK_2 ARP1 actin related protein 1 homolog A (chains A, B, C, D, E, F, G, I)
MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP
KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN
RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI
MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ
YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVL
SGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSK
KEYEEDGARSIHRKTF

Sequence of entity 3 (H), FASTA

>8PTK_3 Actin, cytoplasmic 1 (chains H)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF

Sequence of entity 4 (J), FASTA

>8PTK_4 Arp11 (chains J)
MPLYEGLGSGGEKTAVVIDLGEAFTKCGFAGETGPRCIIPSVIKKAGMPKPIKVVQYNIN
TEELYSYLKEFIHILYFRHLLVNPRDRRVVVIESVLCPSHFRETLTRVLFKYFEVPSVLL
APSHLMALLTLGINSAMVLDCGYRESLVLPIYEGIPVLNCWGALPLGGKALHKELETQLL
EQCTVDTGAAKEQSLPSVMGSIPEGVLEDIKVRTCFVSDLTRGLKIQAAKFNIDGNTERP
SPPPNVDYPLDGEKILHVLGSIRDSVVEILFEQDNEEKSVATLILDSLMQCPIDTRKQLA
ENLVIIGGTSMLPGFLHRLLAEIRYLVEKPKYKKTLGTKTFRIHTPPAKANCVAWLGGAI
FGALQDILGSRSVSKEYYNQTGRIPDWCSLNNPPLEMVFDVGKSQPPLMKRAFSTEK

Sequence of entity 5 (K), FASTA

>8PTK_5 Capping protein (Actin filament) muscle Z-line, alpha 1 (chains K)
MADFEDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMD
QFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSW
RESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFT
ITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQ
TAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA

Sequence of entity 6 (L), FASTA

>8PTK_6 F-actin-capping protein subunit beta (chains L)
MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYL
LCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVY
LWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTN
KSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIV
NGLRSVQTFADKSKQEALKNDLVEALKRKQQC

Sequence of entity 7 (M, N, P, Q), FASTA

>8PTK_7 Dynactin subunit 2 (chains M, N, P, Q)
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAELEELTSTSVEHIIVNPNAAYDKFK
DKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVE
KIKMTVKESATEEKLTPVVLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLL
LQLEATKNTKGAGSGGKTTSGSPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELEA
TVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKH
KASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTT
QQMIACSLKDNATLLTQVQTTMRENLSTVEGNFANIDERMKKLGK

Sequence of entity 8 (O, R), FASTA

>8PTK_8 Dynactin subunit 3 (chains O, R)
MAGVTDVQRLQARLEELERWVYGPGGSRGSRKVADGLVKVQVALGNIASKRERVKILYKK
IEDLIKYLDPEYMDRIAIPDASKLQFILAEEQFILSQVALLEQVEALVPMLDSAHIKAVP
EHAARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAKQ
VKPAEE

Sequence of entity 9 (S, T), FASTA

>8PTK_9 Dynactin subunit 1 (chains S, T)
MAQSKRHVYSRTPSGSRMSAEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGV
ILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKVLRRE
GTDSNAKTSKLRGPKPKKAPTARKTTTRRPKPTRPASTGVAGASSSLGPSGSASAGELSS
SEPSTPAQTPLAAPIIPTPALTSPGAAPPLPSPSKEEEGLRAQVRDLEEKLETLRLKRAE
DKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADT
ADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQL
KQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAE
STIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARE
TELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEA
SVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPG
GDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSL
SLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPL
TKAIKYYQHLYSIHLAEQPEDSTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEASDI
ALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGAQVSDTLLDCRKHLTWVVAV
LQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGTPSSSPYECLRQSCNILISTM
NKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLEDRETVIKELKKSLK
IKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLRKKEKEFEETMDALQ
ADIDQLEAEKAELKQRLNSQSKRTIEGIRGPPPSGIATLVSGIAGEEQQRGGAPGQAPGI
VPGPGLVKDSPLLLQQISAMRLHISQLQHENSVLKGAQMKASLAALPPLHVAKLSLPPHE
GPGSELAAGALYRKTNQLLETLNQLSTHTHVVDITRSSPAAKSPSAQLLEQVTQLKSLSD
TIEKLKDEVLKETVSQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLG
QRHRLVLTQEQLHQLHDRLIS

Sequence of entity 10 (U), FASTA

>8PTK_10 Dynactin 6 (chains U)
MAEKTQKSVKIAPGAVVCVESEIRGDVTIGPRTVIHPKARIIAEAGPIVIGEGNLIEEQA
LIINAHPDNITPDAEDSEPKPMIIGTNNVFEVGCYSQAMKMGDNNVIESKAYVGRNVILT
SGCIIGACCNLNTFEVIPENTVIYGADCLRRVQTERPQPQTLQLDFLMKILPNYHHLKKT
MKGSSTPVKN

Sequence of entity 11 (W), FASTA

>8PTK_11 Dynactin subunit 5 (chains W)
MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRH
CVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRC
VLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPECTQELMIDVTKSYYQKFLPLT
QV

Sequence of entity 12 (X, x), FASTA

>8PTK_12 C-Jun-amino-terminal kinase-interacting protein 3 (chains X, x)
SNIEFLKMMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVK
ELMPLVVNVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRRQAEEKFIEFED
ALEQEKKELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQ
TYVEHIERSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKLVPAGDHW
HLSDLGQLQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQ
PLGDYGVGSKNSKRAREKRDSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDM
CPETRLDRTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDF
FGMGKEVGNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLE
NRIKELEEELKRVKSEAIIARREPKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLM
ERNQYKERLMELQEAVRWTEMIRASREGSGSGRWSHPQFEK

Ligands and cofactors

ID	Name	Formula	Copies
ANP	Phosphoaminophosphonic acid-adenylate ester	C10 H17 N6 O12 P3	4
MG	Magnesium ion	Mg	6
ZN	Zinc ion	Zn	3
ATP	Adenosine-5'-triphosphate	C10 H16 N5 O13 P3	6
ADP	Adenosine-5'-diphosphate	C10 H15 N5 O10 P2	16

Primary citation

Molecular mechanism of dynein-dynactin complex assembly by LIS1. Singh, K., Lau, C.K., Manigrasso, G. et al. Science (2024) 383:eadk8544-eadk8544. DOI 10.1126/science.adk8544 · PubMed

Other PDB entries of the same protein (UniProt P43034 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7MT1 1.3 Å, Crystal structure of Human Platelet-activating factor acetylhydrolase IB subunit beta…
9E0Z 2.86 Å, Dimeric motor domains from phi-like dynein-1 bound to a Lis1 dimer under Nde1-Lis1…
9E11 2.86 Å, Dimeric motor domains from phi-like dynein-1 bound to a Lis1 dimer under Lis1 condition
9DZY 3.1 Å, Cryo-EM structure of Pre-Chi dynein bound to Lis1
9E0T 3.1 Å, Cryo-EM structure of human cytoplasmic dynein-1 bound to LIS1 in the presence of ATP
8FDT 3.2 Å, Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex…
9E0W 3.2 Å, Cryo-EM structure of human cytoplasmic dynein-1 bound to LIS1 in the presence of ATP
8FDU 3.3 Å, Engineered human dynein motor domain in the microtubule-unbound state with LIS1 complex…
9E22 3.3 Å, Cryo-EM structure of human cytoplasmic dynein-1 bound to LIS1 in the presence of ATP
8PQY 3.8 Å, Cytoplasmic dynein-1 motor domain bound to LIS1
9YNC 3.93 Å, Motor domains of phi-like human dynein-1 bound to dynactin-p150glued and LIS1
8DYV 3.97 Å, Structure of human cytoplasmic dynein-1 bound to one Lis1

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