Alpha-centractin (ACTR1A) is a 349-residue protein from Sus scrofa. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: F2Z5G5.
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The mean pLDDT of this model is 84.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 73% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 12% |
What pLDDT means and how to read it
Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules
Part of the ACTR1A/ACTB filament around which the dynactin complex is built (PubMed:25814576, PubMed:28602352, PubMed:29420470, PubMed:33734450, PubMed:36071160). The filament contains 8 copies of ACTR1A and 1 ACTB. Interacts with dynein and adapters such as BICD2 (PubMed:25814576). Interacts with BCCIP (isoform 2/alpha) (By similarity)
Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cell cortex
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7Z8I | EM | 3.3 Å | A/B/C/D/E/F=1-310 |
| 7Z8M | EM | 3.37 Å | G/I=1-310 |
| 6F1U | EM | 3.4 Å | B/D/F=1-310 |
| 5AFU | EM | 3.5 Å | A/B/C/D/E/F/G/I=7-310 |
| 6F1T | EM | 3.5 Å | A/B/C/D/E/F/G/I=1-310 |
| 6ZNL | EM | 3.8 Å | A/B/C/D/E/F/G/I=1-310 |
| 5ADX | EM | 4.0 Å | A/B/C/D/E/F/G/I=7-310 |
| 6ZNM | EM | 4.1 Å | G/I=1-310 |
| 7Z8K | EM | 4.37 Å | F=1-310 |
| 6ZNN | EM | 4.5 Å | G/I=1-310 |
| 9HHL | EM | 6.53 Å | A/B/C/D/E/F/G/I=1-310 |
| 6F38 | EM | 6.7 Å | A/B/C/D/E/F/G/I=1-310 |
| 6ZNO | EM | 6.8 Å | G/I=1-310 |
| 6F3A | EM | 8.2 Å | A/B/C/D/E/F/G/I=1-310 |
| 6ZO4 | EM | 8.2 Å | G/I=1-310 |
| 5NW4 | EM | 8.7 Å | G/H/O/P/Q/T/U/W=1-310 |
| 8PTK | EM | 10.0 Å | A/B/C/D/E/F/G/I=1-310 |
| 7Z8F | EM | 20.0 Å | A/B/C/D/E/F/G/I=1-310 |
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