8PV6: Large ribosomal subunit protein uL10
Chaetomium thermophilum pre-60S State 3 - post-5S rotation with Rix1 complex with Foot - composite structure. Determined by electron microscopy at 2.94 Å resolution. Released 15 Nov 2023.
- Method
- Electron microscopy
- Resolution
- 2.94 Å
- Organism
- Thermochaetoides thermophila DSM 1495
- Chains
- 64
- Atoms
- 172,014
- Mol. weight
- 3378.63 kDa
- Ligands
- GTP, MG, ZN
- Released
- 15 Nov 2023
Explore 8PV6 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8PV6 contains 666 α-helices and 529 β-strands across 60 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain Cb: 9 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-8 | 3 | |
| α-helix | 12-14 | 3 | |
| α-helix | 19-27 | 9 | |
| α-helix | 29-37 | 9 | |
| α-helix | 41-43 | 3 | |
| α-helix | 45-48 | 4 | |
| β-strand | 51-52 | 2 | 140 |
| β-strand | 57-58 | 2 | 140 |
| α-helix | 62-70 | 9 | |
| α-helix | 72-83 | 12 | |
| α-helix | 88-95 | 8 | |
| β-strand | 98-100 | 3 | 97 |
Chain Cd: 26 helices, 18 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-14 | 8 | |
| α-helix | 16-17 | 2 | |
| β-strand | 18 | 1 | 142 |
| β-strand | 20 | 1 | 142 |
| α-helix | 32-38 | 7 | |
| β-strand | 47-48 | 2 | 143 |
| β-strand | 54-56 | 3 | 143 |
| α-helix | 64-66 | 3 | |
| β-strand | 68-69 | 2 | 59 |
| α-helix | 74-77 | 4 | |
| β-strand | 79-83 | 5 | 62 |
| α-helix | 85-100 | 16 | |
| β-strand | 104-107 | 4 | 103 |
| α-helix | 109-111 | 3 | |
| α-helix | 114-117 | 4 | |
| α-helix | 131-138 | 8 | |
| α-helix | 141-144 | 4 | |
| α-helix | 161-184 | 24 | |
| α-helix | 206 | 1 | |
| β-strand | 207 | 1 | 144 |
| α-helix | 208-211 | 4 | |
| α-helix | 220-232 | 13 | |
| β-strand | 235-241 | 7 | 145 |
| α-helix | 251-259 | 9 | |
| β-strand | 265-271 | 7 | 145 |
| α-helix | 273-275 | 3 | |
| α-helix | 278-289 | 12 | |
| β-strand | 294-296 | 3 | 145 |
| β-strand | 298 | 1 | 146 |
| β-strand | 305 | 1 | 146 |
| α-helix | 307-320 | 14 | |
| β-strand | 327-333 | 7 | 145 |
| α-helix | 339-347 | 9 | |
| β-strand | 365-368 | 4 | 145 |
| β-strand | 373-377 | 5 | 145 |
| α-helix | 390-396 | 7 | |
| α-helix | 407-409 | 3 | |
| α-helix | 411-417 | 7 | |
| α-helix | 420-427 | 8 | |
| α-helix | 435-446 | 12 | |
| β-strand | 449 | 1 | 147 |
| β-strand | 455 | 1 | 147 |
| α-helix | 457-470 | 14 | |
| α-helix | 477-481 | 5 | |
Chain Ce: 19 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4 | 1 | 151 |
| α-helix | 26-31 | 6 | |
| α-helix | 36-50 | 15 | |
| α-helix | 89-93 | 5 | |
| α-helix | 99-100 | 2 | |
| α-helix | 185-186 | 2 | |
| α-helix | 187-190 | 4 | |
| α-helix | 192-194 | 3 | |
| β-strand | 197 | 1 | 152 |
| α-helix | 201-204 | 4 | |
| α-helix | 207-210 | 4 | |
| α-helix | 211-213 | 3 | |
| β-strand | 214 | 1 | 51 |
| α-helix | 219-263 | 45 | |
| α-helix | 297-300 | 4 | |
| α-helix | 301-331 | 31 | |
| α-helix | 333-352 | 20 | |
| β-strand | 366 | 1 | 152 |
| β-strand | 372 | 1 | 153 |
| α-helix | 375-381 | 7 | |
| α-helix | 386-388 | 3 | |
| α-helix | 402-413 | 12 | |
| β-strand | 418 | 1 | 153 |
| α-helix | 425-428 | 4 | |
| β-strand | 430-434 | 5 | 154 |
| α-helix | 436-440 | 5 | |
Chain CF: 20 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 9-11 | 3 | |
| α-helix | 20-33 | 14 | |
| α-helix | 34-36 | 3 | |
| β-strand | 39-44 | 6 | 23 |
| α-helix | 53-59 | 7 | |
| β-strand | 64-66 | 3 | 23 |
| α-helix | 70-77 | 8 | |
| α-helix | 89-92 | 4 | |
| α-helix | 93-95 | 3 | |
| β-strand | 100-105 | 6 | 23 |
| α-helix | 109-118 | 10 | |
| β-strand | 121-123 | 3 | 24 |
| α-helix | 124-126 | 3 | |
| α-helix | 129 | 1 | |
| β-strand | 130 | 1 | 25 |
| α-helix | 131 | 1 | |
| β-strand | 135-137 | 3 | 26 |
| α-helix | 138 | 1 | |
| β-strand | 140-141 | 2 | 27 |
| β-strand | 143 | 1 | 28 |
| α-helix | 151-153 | 3 | |
| α-helix | 155 | 1 | |
| β-strand | 156 | 1 | 28 |
| α-helix | 157-158 | 2 | |
| α-helix | 159-161 | 3 | |
| α-helix | 162-167 | 6 | |
| β-strand | 172-175 | 4 | 27 |
| β-strand | 178-181 | 4 | 27 |
| α-helix | 190-191 | 2 | |
| β-strand | 192-195 | 4 | 26 |
| β-strand | 200 | 1 | 25 |
| α-helix | 203-211 | 9 | |
| β-strand | 217-219 | 3 | 24 |
| β-strand | 222-228 | 7 | 23 |
| β-strand | 233-236 | 4 | 23 |
| α-helix | 238-242 | 5 | |
Chain Ch: 5 helices, 34 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 133-135 | 3 | |
| β-strand | 137-142 | 6 | 156 |
| β-strand | 149-154 | 6 | 157 |
| β-strand | 161-166 | 6 | 157 |
| β-strand | 170-175 | 6 | 157 |
| β-strand | 180-186 | 7 | 157 |
| β-strand | 192-197 | 6 | 158 |
| β-strand | 204-208 | 5 | 158 |
| β-strand | 213-217 | 5 | 158 |
| β-strand | 222-228 | 7 | 158 |
| β-strand | 235-240 | 6 | 159 |
| α-helix | 241-242 | 2 | |
| α-helix | 243-245 | 3 | |
| β-strand | 252-257 | 6 | 159 |
| β-strand | 261-266 | 6 | 159 |
| β-strand | 271-277 | 7 | 159 |
| β-strand | 283-288 | 6 | 160 |
| β-strand | 293-298 | 6 | 160 |
| β-strand | 303-307 | 5 | 160 |
| β-strand | 312-317 | 6 | 160 |
| β-strand | 324-329 | 6 | 161 |
| α-helix | 332-337 | 6 | |
| α-helix | 350-365 | 16 | |
| β-strand | 366-367 | 2 | 162 |
| β-strand | 370-371 | 2 | 162 |
| β-strand | 375-379 | 5 | 161 |
| β-strand | 384-387 | 4 | 161 |
| β-strand | 398-400 | 3 | 161 |
| β-strand | 407-412 | 6 | 163 |
| β-strand | 418-423 | 6 | 163 |
| β-strand | 428-432 | 5 | 163 |
| β-strand | 438-442 | 5 | 163 |
| β-strand | 449-454 | 6 | 164 |
| β-strand | 460-465 | 6 | 164 |
| β-strand | 470-474 | 5 | 164 |
| β-strand | 479-484 | 6 | 164 |
| β-strand | 491-496 | 6 | 156 |
| β-strand | 503-507 | 5 | 156 |
| β-strand | 512-516 | 5 | 156 |
Chain CH: 37 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 8-9 | 2 | |
| α-helix | 13-26 | 14 | |
| α-helix | 38-66 | 29 | |
| α-helix | 68-69 | 2 | |
| α-helix | 70-72 | 3 | |
| α-helix | 75-84 | 10 | |
| α-helix | 87-115 | 29 | |
| α-helix | 121-140 | 20 | |
| α-helix | 143-158 | 16 | |
| β-strand | 168-173 | 6 | 34 |
| α-helix | 179-186 | 8 | |
| β-strand | 204-210 | 7 | 34 |
| β-strand | 213-219 | 7 | 34 |
| α-helix | 228-230 | 3 | |
| α-helix | 233-244 | 12 | |
| β-strand | 248-254 | 7 | 34 |
| α-helix | 263-273 | 11 | |
| α-helix | 274-277 | 4 | |
| β-strand | 281-287 | 7 | 34 |
| α-helix | 299-309 | 11 | |
| β-strand | 314-318 | 5 | 34 |
| β-strand | 320 | 1 | 35 |
| β-strand | 325 | 1 | 35 |
| α-helix | 327-348 | 22 | |
| α-helix | 356-358 | 3 | |
| α-helix | 359-368 | 10 | |
| β-strand | 370-371 | 2 | 36 |
| α-helix | 379-381 | 3 | |
| α-helix | 390-393 | 4 | |
| α-helix | 401-403 | 3 | |
| α-helix | 404-410 | 7 | |
| α-helix | 417-419 | 3 | |
| α-helix | 430-434 | 5 | |
| β-strand | 440-441 | 2 | 37 |
| β-strand | 444-445 | 2 | 37 |
| α-helix | 446-449 | 4 | |
| α-helix | 454-471 | 18 | |
| α-helix | 483-509 | 27 | |
| α-helix | 516-519 | 4 | |
| α-helix | 520-522 | 3 | |
| α-helix | 524 | 1 | |
| β-strand | 525-526 | 2 | 38 |
| α-helix | 527-537 | 11 | |
| α-helix | 541-544 | 4 | |
| α-helix | 546-549 | 4 | |
| β-strand | 551 | 1 | 38 |
| α-helix | 583-596 | 14 | |
| α-helix | 610-622 | 13 | |
| α-helix | 625-629 | 5 | |
| α-helix | 646-649 | 4 | |
Chain CI: 3 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 187-192 | 6 | 42 |
| α-helix | 200-210 | 11 | |
| β-strand | 213-220 | 8 | 42 |
| β-strand | 227-235 | 9 | 42 |
| α-helix | 238-248 | 11 | |
| β-strand | 251-253 | 3 | 43 |
| β-strand | 256-258 | 3 | 43 |
| β-strand | 259-262 | 4 | 42 |
| α-helix | 270-272 | 3 | |
Chain CJ: 24 helices, 15 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-6 | 4 | |
| α-helix | 12-15 | 4 | |
| β-strand | 16-18 | 3 | 49 |
| α-helix | 19-26 | 8 | |
| α-helix | 30-40 | 11 | |
| β-strand | 45 | 1 | 49 |
| α-helix | 50-53 | 4 | |
| β-strand | 63-65 | 3 | 49 |
| α-helix | 66-72 | 7 | |
| α-helix | 77-97 | 21 | |
| α-helix | 100-108 | 9 | |
| α-helix | 113-116 | 4 | |
| α-helix | 124-130 | 7 | |
| α-helix | 134-151 | 18 | |
| α-helix | 155-156 | 2 | |
| α-helix | 162-182 | 21 | |
| β-strand | 185-190 | 6 | 50 |
| β-strand | 191 | 1 | 51 |
| β-strand | 195-201 | 7 | 50 |
| β-strand | 204-210 | 7 | 50 |
| α-helix | 224-248 | 25 | |
| β-strand | 251 | 1 | 52 |
| α-helix | 255 | 1 | |
| β-strand | 256-257 | 2 | 53 |
| α-helix | 259-264 | 6 | |
| α-helix | 267-270 | 4 | |
| β-strand | 271-272 | 2 | 53 |
| β-strand | 275 | 1 | 52 |
| α-helix | 363-365 | 3 | |
| β-strand | 371-374 | 4 | 54 |
| α-helix | 380-390 | 11 | |
| β-strand | 394-397 | 4 | 54 |
| α-helix | 399-401 | 3 | |
| β-strand | 417-419 | 3 | 54 |
| β-strand | 454-456 | 3 | 54 |
| α-helix | 459-467 | 9 | |
| α-helix | 470-472 | 3 | |
| α-helix | 473-476 | 4 | |
| α-helix | 481-484 | 4 | |
52 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 26S rRNA | C1 | RNA | 3342 | Thermochaetoides thermophila DSM 1495 | |
| 5.8S rRNA | C2 | RNA | 156 | Thermochaetoides thermophila DSM 1495 | |
| ITS2 | C3 | RNA | 162 | Thermochaetoides thermophila DSM 1495 | |
| 5S rRNA | C4 | RNA | 119 | Thermochaetoides thermophila DSM 1495 | |
| Large ribosomal subunit protein uL10 | CF | protein | 270 | Thermochaetoides thermophila DSM 1495 | G0S616 (AlphaFold model) |
| Nucleolar GTP-binding protein 1 | CH | protein | 661 | Thermochaetoides thermophila DSM 1495 | G0S8F1 (AlphaFold model) |
| Putative RNA-binding protein | CI | protein | 414 | Thermochaetoides thermophila DSM 1495 | G0S1H0 (AlphaFold model) |
| Pescadillo homolog | CJ | protein | 679 | Thermochaetoides thermophila DSM 1495 | G0SHX6 (AlphaFold model) |
| Ribosome biogenesis protein NSA2 homolog | CK | protein | 261 | Thermochaetoides thermophila DSM 1495 | G0S081 |
| Putative GTP binding protein | CL | protein | 558 | Thermochaetoides thermophila DSM 1495 | G0SEW3 |
| 60S ribosomal protein l7-like protein | CM, LF | protein | 249 | Thermochaetoides thermophila DSM 1495 | G0SFL0 |
| Eukaryotic translation initiation factor 6 | CN | protein | 246 | Thermochaetoides thermophila DSM 1495 | G0S683 |
49 more molecules are not listed.
Sequence of entity 1 (C1), FASTA
>8PV6_1 26S rRNA (chains C1)
AGGUUGACCUCGGAUCAGGUAGGAGGACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGG
AAAAGAAACCAACAGGGAUUGCCCUAGUAACGGCGAGUGAAGCGGCAACAGCUCAAAUUU
GAAAGCUGGCUUCGGCCCGCGUUGUAAUUUGGAGAGGAUGCUUUGGGCGAGGCUCCUUCU
GAGUUCCCUGGAACGGGACGCCACAGAGGGUGAGAGCCCCGUAUAGUUGGAAGCCAAGCC
UGUGUAAAGCUCCUUCGACGAGUCGAGUAGUUUGGGAAUGCUGCUCAAAAUGGGAGGUAA
AUUUCUUCUAAAGCUAAAUACCGGCCAGAGACCGAUAGCGCACAAGUAGAGUGAUCGAAA
GAUGAAAAGCACUUUGAAAAGAGGGUUAAAUAGCACGUGAAAUUGUUGAAAGGGAAGCGC
UUGUGACCAGACUUGCGCCCGGCGGAUCAUCCGGUGUUCUCACCGGUGCACUCCGCCGGG
CUCAGGCCAGCAUCGGUUCUGGCGGGGGGAUAAAGGCCCAGGGAAUGUGGCUCCUCCGGG
AGUGUUAUAGCCCUGGGUGUAAUACCCUCGCCGGGACCGAGGACCGCGCUCUGCAAGGAU
GCUGGCGUAAUGGUCACCAGCGACCCGUCUUGAAACACGGACCAAGGAGUCAAGGUUUUG
CGCGAGUGUUUGGGUGUAAAACCCGCACGCGUAAUGAAAGUGAACGUAGGUGAGAGCUUC
GGCGCAUCAUCGACCGAUCCUGAUGUAUUCGGAUGGAUUUGAGUAGGAGCGUUAAGCCUU
GGACCCGAAAGAUGGUGAACUAUGCUUGGAUAGGGUGAAGCCAGAGGAAACUCUGGUGGA
GGCUCGCAGCGGUUCUGACGUGCAAAUCGAUCGUCAAAUCUGAGCAUGGGGGCGAAAGAC
UAAUCGAACCAUCUAGUAGCUGGUUACCGCCGAAGUUUCCCUCAGGAUAGCAGUGUCGAC
CUUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGGGACUCGGGGGCGAUUUUUAGCCUUCAU
CCAUUCUCAAACUUUAAAUAUGUAAGAAGCCCUUGUUACUUAACUGAACGUGGGCAUUCG
AAUGUAUCGACACUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCG
AACGCGGGGUUAAGGUGCCGGAGUGGACGCUCAUCAGACACCACAAAAGGCGUUAGUACA
UCUUGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGACUGUGUAACAACUC
ACCUGCCGAAUGUACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGUCCCACCCAUACCCCG
CCCUCAGGGUAGAAACGAUGCCCUGAGGAGUAGGCGGCCGUGGAGGUCAGUGACGAAGCC
UAGGGCGUGAGCCCGGGUCGAACGGCCUCUAGUGCAGAUCUUGGUGGUAGUAGCAAAUAC
UUCAAUGAGAACUUGAAGGACCGAAGUGGGGAAAGGUUCCAUGUGAACAGCGGUUGGACA
UGGGUUAGUCGAUCCUAAGCCAUAGGGAAGUUCCGUUUCAAAGGGGCACUCGUGCCCCGU
GUGGCGAAAGGGAAGCCGGUUAAUAUUCCGGCACCUGGAUGUGGGUUUUGCGCGGCAACG
CAACUGAACGCGGAGACGACGGCGGGGGCCCCGGGCAGAGUUCUCUUUUCUUCUUAACGG
UCUAUCACCCUGGAAACAGUUUGUCUGGAGAUAGGGUUUAAUGGCCGGAAGAGCCCGACA
CUUCUGUCGGGUCCGGUGCGCUCUCGACGUCCCUUGAAAAUCCGCGGGAGGGAAUAAUUC
UCACGCCAGGUCGUACUCAUAACCGCAGCAGGUCCCCAAGGUGAACAGCCUCUGGUUGAU
AGAACAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGUAACUUCGGGAAAAGGAUUGG
CUCUAAGGGUUGGGCACGUUGGGCUUUGGGCGGACGCCCUGGGAGCAGAGGGCCUCUAGC
CGGGCAACCGGCCGGCGGCCCUCAGCACCCGGGGUUGAAGCCCUUAGCAGGCUUCGGCCG
UCCGGCGUGCGGUUAACAACCAACUUAGAACUGGUACGGACAGGGGGAAUCUGACUGUCU
AAUUAAAACAUAGCAUUGCGAUGGCCAGAAAGUGGUGUUGACGCAAUGUGAUUUCUGCCC
AGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAAC
UAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGA
UUAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGG
CUUGGCAAAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUG
AAAAGACAUAGGAGGUGUAGAAUAGGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACUC
CUAUUGUUUUUUUACUUAUUCAAUGAAGCGGGGCUGGACUUGCGUCCAACUUCUGGAGUU
AAGGUCCUUCGCGGGCCGACCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGG
CGGCACAUCUGUUAAACCAUAACGCAGGUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAU
CUCCAGUAGAACAAAAGGGUAAAAGUCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAAC
CAUGAAAGUGUGGCCUAUCGAUCCUUUAGUCCCUCGAAAUUUGAGGCUAGAGGUGCCAGA
AAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUU
UGAUCCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUU
GUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUU
ACCCUACUGAUGAACUCGUCGCAAUGGUAAUUCAGCUUAGUACGAGAGGAACCGCUGAUU
CAGAUAAUUGGUUUUUGCGGUUGUCCGACCGGGCAGUGCCGCGAAGCUACCAUCUGCUGG
AUAAUGGCUGAACGCCUCUAAGUCAGAAUCCAUGCCAGAACGCGACGAUACUACCCGCAC
GUUGUAGACGUAUAAGAAUAGGCUCCGGCCUCGUAUCCUAGCAGGCGAUUCCUCCGCCGG
CCUCGAAGUGGCCGUCGGUAAUUCGCGUAUUGCAAUUUAGACACGCGCGGGAUCAAAUCC
UUUGCAGACGACUUAGAUGUGCGAAAGGGUCCUGUAAGCAGUAGAGUAGCCUUGUUGUUA
CGAUCUGCUGAGGGUAAGCCCUCCUUCGCCUAGAUUUCCCAG
Sequence of entity 2 (C2), FASTA
>8PV6_2 5.8S rRNA (chains C2)
AAACUUUCAACAACGGAUCUCUUGGUUCUGGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
AAGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCG
CCGGUAUUCCGGCGGGCAUGCCUGUUCGAGCGUCAU
Sequence of entity 3 (C3), FASTA
>8PV6_3 ITS2 (chains C3)
UUCAACCAUCAAGCCCUGGGCUUGUGUUGGGGACCCGCGGCUGCUCGCGGGCCCUGAAAA
GCAGUGGCGGGCUCGCUAGUCACACCGAGCGUAGUAGAACUUCUAUUCGAUCUCGCUCAG
GGCGUGCGGCGGGUGCCAGCCGUAAAACCCCAGCUUCUUCUA
Sequence of entity 4 (C4), FASTA
>8PV6_4 5S rRNA (chains C4)
ACGUACGACCAUACCCAGUGGAAAGCACGGCAUCCCGUCCGCUCUGCCCUAGUUAAGCCA
CUGAGGGCCCGGUUAGUAGUUGGGUCGGUGACGACCAGCGAAUCCCGGGUGUUGUACGU
Sequence of entity 5 (CF), FASTA
>8PV6_5 Large ribosomal subunit protein uL10 (chains CF)
MPKSKRARVYHLTQVNKKGREAKERLFSNIRETIPKYQHCFVFSVDNMRNNYLKDVRHEL
NDCRIFFGKTKLMARALGTTPEEEQADGLHRLTRYLTGTVGLLFTNRDPADIESYFSNLS
QVDFARAGTVAPRTVTVPPGIVYSTGGEVPPEHDVPVSHTLEPELRRLGMPVRMIKGKVC
LGDEKGEASEGYTICKEGEVLDSRQTRLLKLFSICLSEFKVSLLGYWSSASGEVTELEAG
KTRPKREGNRRQAMNGDEMDEDQSSDEDSD
Sequence of entity 6 (CH), FASTA
>8PV6_6 Nucleolar GTP-binding protein 1 (chains CH)
MTGWKDIPPVPTAQEFIDIVLSRTQRRLPTQIRPGFKISRIRAFYTRKVKFTQETCSEKF
GAIISSFPVLSDQHPFHRDLMNILYDADHFKVALGQISTAKNLIETISRDYVRLLKYAQS
LYQCKQLKRAALGRMATLIKRLKDPLIYLDQVRQHLARLPDINPTTRTLLVAGFPNVGKS
SFVRSVTRADTPVEPYAFTTKSLFVGHLDYKYLRYQVIDTPGILDHPLEEMNTIEMQSVT
ALAHLRAAVLYFMDISEQCGFSLKAQINLFKSIKPLFANKMVFIVLNKMDIKKFEELDPE
MQQEINDLTKSGEVEILRASCATQEGVQEVKNHVCERLLVERVSQKLKAGTHSNGNIGTR
LQEVMARIHVATPMDGTTRETFIPEAVKNLKKYDKNDPNRRVLARDIEEANGGAGVFNVD
LRKDWILENPEWKYDKIPEIFDGKNVYDYIDPDIDAKLQALEEEEERLEKEGFYDEDDDL
PDEEEEEILQKAEYIREQHALIRNEAKMRKSLKNRAIIPRKAVKKPLSQLEDHLDQLGVD
TEAIGLRARAQTAQSSRGRSLVRSRGTTADPDAMDIDDGAASAKERLARSRSRARSVAAT
NRLQDGVQGTTLRSKAERQAKLAQRKMNRMARQGEADRHIHASMPKHLFSGKRTIGKTDR
R
Sequence of entity 7 (CI), FASTA
>8PV6_7 Putative RNA-binding protein (chains CI)
MAAELRKKKSKSAVADADAAISKKEKATKVTKATPKAEKRKAPEEASPVAIKKQKADKDA
VVKKAAVAAEDKIAEKPVKSVLKKETSAKAKEAAKPKKKQEKVEEEEEEALENADAAFGS
DEESELDEQTKALMDTLDDGEESDEDESKQVSTFKKGQDVGKIPTPKKAPQKQTNGDSKP
AGDSQPGVMYIARLPHGFYEHELRGYFSQFGEITRLRVVRNKKTGASRHRAFIEFADAEV
ADIAARTMDKYLLFGHILTCKIVPPAQVHPDLFKGANRRFKVVPWNKMAGRQLERPLSES
QWQVKVAKEEQRRAARAEKLKEMGYEFEAPALKVPKAKPVLENGEEEKKAIETAPAPAVE
EKESKEVAKRQAEEEVEEKAPAPKTKKVKEDKPAKEAATISAPKKGKKSKKTKS
Sequence of entity 8 (CJ), FASTA
>8PV6_8 Pescadillo homolog (chains CJ)
MGKAKKKGKSGAARNYMTRTQAVKKLQLSLPDFRKLCIWKGIYPREPRDRRKVNKSATAS
TTFYYTKDIQYLLHEPLLQKFREQKALEKKISRALGRGDVSNAARLERNANLPEKTGKPR
YTLNHIIRERYPTFQDALRDLDDCLSMLFLFANLPSTTAVPAKMIARCERLCHEFQHYLI
VTHSLRKSFLSIKGIYYQANIQGEDILWLVPYKFNQRIVGDVDFRIMGTFVEFYMTLLGF
VNYRLYTSIGLKYPPKFDQVKDDQGAELAAFSLEGLNLASQNGEQKAITNGEEHGPDPKV
QAEVDKLVAKLREEEQQANGDKTDEKGEENEGDDKPSDAIDKFEPVAPGGDVLPQPSYSS
SDPSQLFANFTFFLSRETPRQPLEFILRAFGCKRIGWDAVLGEGAFTTDESDPRITHQII
DRPVIRAAVSEDGDGEDNQTSQKLAPNGRYPGRIYVQPQWVWDSINDEELKPPELYAPGA
QLPPHLSPFVKPTQGQYDPTKPLEEQQTEAEALEAELEDAQAQQEGSDEESGSEVENDMS
VASDEEDEQEDDFGGFSDEDEEQSDEGSEEGDEEEDDDEEEEATLERQRELEAELAGKAV
SKGKPLDPKVKAKLEAKKALERKKKQEAEELERAKGMLSKKKRKLFEQMQYSNAKKNAED
AKLRAKRRRIEKEMAAKKA
Sequence of entity 9 (CK), FASTA
>8PV6_9 Ribosome biogenesis protein NSA2 homolog (chains CK)
MPQNEYIERHRKLHGRRLDAEERARKKAAREGHKNSENAQNLRGLRAKLYAKQRHAQKIQ
MRKAIKQHEERNVKGRPAEKEPSDPIPSYLLDRANPTTAKALSSQIKNKRAEKAARFSVP
IPKVRGISEEEMFKVVKTGKKTHKKGWKRIVTKPTFVGPDFTRRPVKYERFIRPMGLRYK
KANVTHPTLNVTVQLPILSVKKNPSNPLYTQLGVLTKGTIIEVNVSDLGIVTASGKIAWG
RYAQITNNPENDGCVNAVLLV
Sequence of entity 10 (CL), FASTA
>8PV6_10 Putative GTP binding protein (chains CL)
MAGTINKPKKPTSKRKTTRLRAKISKRAAEKKRKERKLARKNPEWRSKLKKDPGIPNLFP
YKERLLQQIEEERIRRKEELLRKKELAKAAKTGADGDNKDDEQMQEDDEHMIREEELDLD
DAMDEDGSDVDESNPLAALVRSARKAAEEYEKELQSGSEMDEDDEDDSDDASDAGSDAGV
ITEVHGGATSRKAYDKVFKQVVEQADVILYVLDARDPEGTRSHDVEQAVMAAAGGGKRLM
LILNKVDLVPPPVLKGWLTYLRRFFPTLPLRASNPAPNARTFSHRDITVQSTSAALFRAL
KAYAAARNLKRAIAVGVIGYPNVGKSSVINALLSRLPGSARGGRTPCPAGAEAGVTTAIR
AVKIDSKLTLLDSPGIVFPSTASSQTFIPKNPVEAHAHLVLLNAIPPKQIEDPVPAVTLL
LKRLSATPELMDRLMQVYDIPPLLKDPSQGGDATMDFLVQVARKRGRLGRGGVPNIQAAA
MTVVTDWRDGRIQGWTEPPKIAVEGVKEGNEGKVVRKIADQEVAPDQKIIVTEWAKEFKL
AGLWGDEEQTEEGDKMEA
Sequence of entity 11 (CM, LF), FASTA
>8PV6_11 60S ribosomal protein l7-like protein (chains CM, LF)
MSSTTVPTQNDILVPETLLKKRKSQEKARAERAAALEKRKQANKEKRQVIFKRAEKYVKE
YREQEREKIRLARIAKQQGSFHIPAEAKLVFVIRIKGINKIPPKPRKILQLLRLRQINNG
VFVKVTKATAEMIKIVEPWVAYGYPNLKSVRELIYKRGYGKVNGQRIPLTDNAIIEENLG
KYGIICIEDLIHEIFTVGPNFKQAANFLWPFKLSNPNGGFRPRKFKHFIEGGDLGNREEH
INALIRAMN
Sequence of entity 12 (CN), FASTA
>8PV6_12 Eukaryotic translation initiation factor 6 (chains CN)
MAVRAQFENSNEVGVFATLTNSYCLVALGASENFYSVFEAELQDVIPICRTTIAGTRIIG
RLTAGNRKGLLVPTTTTDQELQHLRNSLPDDIRIQRIEERLSALGNVIVCNDHTALIHPD
LERETEEIIADVLGVEVFRQTIADHVLVGSYMALSNQGGLVHPKTSIQDQDELSSLLGVP
LVAGSVNRGSNVIGGGMVVNDWLAVTGLDTTAPELSVIESVFRLGEGAGPGAINTSMKNT
IVESFY
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 2 |
| MG | Magnesium ion | Mg | 3 |
| ZN | Zinc ion | Zn | 5 |
Primary citation
Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Thoms, M., Lau, B., Cheng, J. et al. EMBO Rep (2023) 24:e57984-e57984. DOI 10.15252/embr.202357984 · PubMed
Other PDB entries of the same protein (UniProt G0S616 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 4NWB 1.8 Å, Crystal structure of Mrt4
- 8PV7 2.12 Å, Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite…
- 8PVL 2.19 Å, Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite…
- 9XB4 2.5 Å, Crystal structure of Mrt4 (L96C) mutant
- 8PVK 2.55 Å, Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite…
- 8PV1 2.56 Å, Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite…
- 8PV2 2.63 Å, Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1
- 8I9Z 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4
- 8IA0 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6
- 8I9X 2.8 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1
- 8PV3 2.8 Å, Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite…
- 8PV5 2.86 Å, Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite…
Browse structure collections
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