8PV8: Large ribosomal subunit protein uL10

Name: PDB 8PV8: Chaetomium thermophilum pre-60S State 4 - post-5S rotation with Rix1 complex without Foot - composite structure
Published: 2024-01-10
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: ribosome

Chaetomium thermophilum pre-60S State 4 - post-5S rotation with Rix1 complex without Foot - composite structure. Determined by electron microscopy at 2.91 Å resolution. Released 10 Jan 2024.

Method: Electron microscopy
Resolution: 2.91 Å
Organism: Thermochaetoides thermophila DSM 1495
Chains: 60
Atoms: 163,368
Mol. weight: 3121.38 kDa
Ligands: GTP, MG, ZN
Released: 10 Jan 2024

Explore 8PV8 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8PV8 contains 589 α-helices and 500 β-strands across 57 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain Cb: 9 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	6-8	3
α-helix	12-14	3
α-helix	19-27	9
α-helix	29-38	10
α-helix	41-43	3
α-helix	45-48	4
β-strand	51-52	2	59
β-strand	57-58	2	59
α-helix	62-69	8
α-helix	72-83	12
α-helix	88-95	8
β-strand	98-100	3	56

Chain Cd: 25 helices, 20 β-strands

Element	Residues	Length	Sheet
α-helix	7-14	8
α-helix	16-17	2
β-strand	18	1	60
β-strand	20	1	60
α-helix	32-38	7
α-helix	40-42	3
β-strand	47-48	2	61
β-strand	54-56	3	61
β-strand	58	1	62
β-strand	61	1	62
β-strand	69	1	32
α-helix	74-77	4
β-strand	79-83	5	35
α-helix	85-100	16
β-strand	104-106	3	63
α-helix	109-111	3
α-helix	131-138	8
α-helix	141-144	4
α-helix	161-184	24
α-helix	206	1
β-strand	207	1	64
α-helix	208-211	4
α-helix	220-232	13
β-strand	235-241	7	65
α-helix	251-259	9
β-strand	265-271	7	65
α-helix	273-275	3
α-helix	278-291	14
β-strand	294-296	3	65
β-strand	298	1	66
β-strand	305	1	66
α-helix	307-320	14
β-strand	327-332	6	65
α-helix	339-347	9
β-strand	365-368	4	65
β-strand	373-377	5	65
α-helix	390-396	7
α-helix	407-409	3
α-helix	411-417	7
α-helix	420-427	8
α-helix	435-446	12
β-strand	449	1	67
β-strand	455	1	67
α-helix	457-470	14
α-helix	477-481	5

Chain CF: 17 helices, 16 β-strands

Element	Residues	Length	Sheet
α-helix	9-11	3
α-helix	20-33	14
α-helix	34-36	3
β-strand	39-44	6	11
α-helix	53-59	7
β-strand	64-66	3	11
α-helix	70-77	8
α-helix	89-92	4
α-helix	93-95	3
β-strand	100-105	6	11
α-helix	109-118	10
β-strand	121-123	3	12
α-helix	129	1
β-strand	130	1	13
α-helix	131	1
β-strand	135-137	3	14
α-helix	138	1
β-strand	140-141	2	15
β-strand	143	1	16
α-helix	151-153	3
α-helix	155	1
β-strand	156	1	16
α-helix	157-158	2
α-helix	162-167	6
β-strand	172-175	4	15
β-strand	178-181	4	15
β-strand	192-195	4	14
β-strand	200	1	13
α-helix	203-211	9
β-strand	217-219	3	12
β-strand	222-228	7	11
β-strand	233-236	4	11
α-helix	238-242	5

Chain Ch: 7 helices, 37 β-strands

Element	Residues	Length	Sheet
α-helix	131-135	5
β-strand	137-142	6	149
β-strand	149-154	6	150
β-strand	161-166	6	150
β-strand	170-175	6	150
β-strand	180-186	7	150
β-strand	192-197	6	151
β-strand	204-208	5	151
β-strand	213-216	4	151
α-helix	222	1
β-strand	223	1	151
α-helix	224	1
β-strand	228	1	151
β-strand	235-240	6	152
α-helix	241-242	2
α-helix	243-245	3
β-strand	247	1	153
β-strand	250	1	153
β-strand	252-257	6	152
β-strand	261-266	6	152
β-strand	272-277	6	152
β-strand	283-288	6	154
β-strand	293-298	6	154
β-strand	303-307	5	154
β-strand	312-317	6	154
β-strand	324-329	6	155
α-helix	332-337	6
α-helix	350-365	16
β-strand	366-367	2	156
β-strand	370-371	2	156
β-strand	375-379	5	155
β-strand	384-387	4	155
β-strand	398-400	3	155
β-strand	407-412	6	157
β-strand	418-423	6	157
β-strand	428-432	5	157
β-strand	438-442	5	157
β-strand	449-454	6	158
β-strand	460-465	6	158
β-strand	470-474	5	158
β-strand	479-484	6	158
β-strand	491-496	6	149
β-strand	503-507	5	149
β-strand	512-516	5	149

Chain CH: 37 helices, 13 β-strands

Element	Residues	Length	Sheet
α-helix	7-9	3
α-helix	13-26	14
α-helix	38-66	29
α-helix	68-69	2
α-helix	70-72	3
α-helix	75-84	10
α-helix	87-115	29
α-helix	121-140	20
α-helix	143-157	15
β-strand	168-173	6	19
α-helix	179-186	8
β-strand	204-210	7	19
β-strand	213-219	7	19
α-helix	228-230	3
α-helix	233-244	12
β-strand	248-254	7	19
α-helix	263-273	11
α-helix	274-277	4
β-strand	281-287	7	19
α-helix	299-308	10
β-strand	314-318	5	19
β-strand	320	1	20
β-strand	325	1	20
α-helix	327-348	22
α-helix	356-358	3
α-helix	359-368	10
β-strand	370-371	2	21
α-helix	379-381	3
α-helix	386-389	4
α-helix	390-393	4
α-helix	400-402	3
α-helix	404-410	7
α-helix	430-432	3
β-strand	440-441	2	22
β-strand	444-445	2	22
α-helix	446-449	4
α-helix	454-471	18
α-helix	483-509	27
α-helix	516-519	4
α-helix	520-522	3
α-helix	524	1
β-strand	525-526	2	23
α-helix	527-537	11
α-helix	541-544	4
α-helix	546-549	4
β-strand	551	1	23
α-helix	583-596	14
α-helix	610-622	13
α-helix	625-629	5
α-helix	646-649	4

Chain CK: 10 helices, 13 β-strands

Element	Residues	Length	Sheet
α-helix	6-14	9
α-helix	20-41	22
α-helix	45-69	25
α-helix	88-90	3
β-strand	123	1	32
α-helix	129-132	4
β-strand	133-138	6	33
β-strand	145-151	7	33
β-strand	155	1	34
α-helix	163-165	3
β-strand	171-172	2	33
α-helix	175-177	3
β-strand	178	1	34
β-strand	181-185	5	35
β-strand	192-202	11	35
α-helix	207-212	6
β-strand	214	1	34
β-strand	220-223	4	35
α-helix	226-228	3
β-strand	231	1	35
β-strand	237-245	9	35
α-helix	249-252	4
β-strand	256-259	4	35

Chain CL: 2 helices, 0 β-strands

Element	Residues	Length	Sheet
α-helix	18-40	23
α-helix	62-79	18

Chain CN: 11 helices, 21 β-strands

Element	Residues	Length	Sheet
β-strand	2-5	4	45
α-helix	13-16	4
β-strand	17-19	3	46
β-strand	24-27	4	46
α-helix	33-42	10
β-strand	48-51	4	46
β-strand	53	1	47
β-strand	56	1	47
α-helix	59-61	3
β-strand	64-65	2	48
β-strand	69-72	4	48
α-helix	78-87	10
β-strand	93-96	4	48
α-helix	104-107	4
β-strand	108-110	3	49
β-strand	114-117	4	49
α-helix	123-132	10
β-strand	136-139	4	49
β-strand	142	1	50
β-strand	145	1	50
α-helix	148-151	4
β-strand	153-154	2	21
β-strand	159-161	3	21
α-helix	167-177	11
β-strand	181-183	3	21
β-strand	186	1	51
β-strand	190	1	51
β-strand	197-199	3	45
β-strand	204-207	4	45
α-helix	212-222	11
α-helix	230-232	3
α-helix	238-244	7

49 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
26S rRNA	C1	RNA	3342	Thermochaetoides thermophila DSM 1495
5.8S rRNA	C2	RNA	156	Thermochaetoides thermophila DSM 1495
Large ribosomal subunit protein uL10	CF	protein	270	Thermochaetoides thermophila DSM 1495	G0S616 (AlphaFold model)
Nucleolar GTP-binding protein 1	CH	protein	661	Thermochaetoides thermophila DSM 1495	G0S8F1 (AlphaFold model)
Ribosome biogenesis protein NSA2 homolog	CK	protein	261	Thermochaetoides thermophila DSM 1495	G0S081 (AlphaFold model)
Putative GTP binding protein	CL	protein	558	Thermochaetoides thermophila DSM 1495	G0SEW3 (AlphaFold model)
Eukaryotic translation initiation factor 6	CN	protein	246	Thermochaetoides thermophila DSM 1495	G0S683
DUF2423 domain-containing protein	CO	protein	120	Thermochaetoides thermophila DSM 1495	G0SHK0
Ribosome biogenesis protein RLP24	CQ	protein	225	Thermochaetoides thermophila DSM 1495	G0S497
Zinc finger domain-containing protein	Cb	protein	117	Thermochaetoides thermophila DSM 1495	G0SB32
Nucleolar GTP-binding protein 2	Cd	protein	627	Thermochaetoides thermophila DSM 1495	G0SBX1
rRNA-processing protein	Cz	protein	123	Thermochaetoides thermophila DSM 1495	G0SCP3

46 more molecules are not listed.

Sequence of entity 1 (C1), FASTA

>8PV8_1 26S rRNA (chains C1)
AGGUUGACCUCGGAUCAGGUAGGAGGACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGG
AAAAGAAACCAACAGGGAUUGCCCUAGUAACGGCGAGUGAAGCGGCAACAGCUCAAAUUU
GAAAGCUGGCUUCGGCCCGCGUUGUAAUUUGGAGAGGAUGCUUUGGGCGAGGCUCCUUCU
GAGUUCCCUGGAACGGGACGCCACAGAGGGUGAGAGCCCCGUAUAGUUGGAAGCCAAGCC
UGUGUAAAGCUCCUUCGACGAGUCGAGUAGUUUGGGAAUGCUGCUCAAAAUGGGAGGUAA
AUUUCUUCUAAAGCUAAAUACCGGCCAGAGACCGAUAGCGCACAAGUAGAGUGAUCGAAA
GAUGAAAAGCACUUUGAAAAGAGGGUUAAAUAGCACGUGAAAUUGUUGAAAGGGAAGCGC
UUGUGACCAGACUUGCGCCCGGCGGAUCAUCCGGUGUUCUCACCGGUGCACUCCGCCGGG
CUCAGGCCAGCAUCGGUUCUGGCGGGGGGAUAAAGGCCCAGGGAAUGUGGCUCCUCCGGG
AGUGUUAUAGCCCUGGGUGUAAUACCCUCGCCGGGACCGAGGACCGCGCUCUGCAAGGAU
GCUGGCGUAAUGGUCACCAGCGACCCGUCUUGAAACACGGACCAAGGAGUCAAGGUUUUG
CGCGAGUGUUUGGGUGUAAAACCCGCACGCGUAAUGAAAGUGAACGUAGGUGAGAGCUUC
GGCGCAUCAUCGACCGAUCCUGAUGUAUUCGGAUGGAUUUGAGUAGGAGCGUUAAGCCUU
GGACCCGAAAGAUGGUGAACUAUGCUUGGAUAGGGUGAAGCCAGAGGAAACUCUGGUGGA
GGCUCGCAGCGGUUCUGACGUGCAAAUCGAUCGUCAAAUCUGAGCAUGGGGGCGAAAGAC
UAAUCGAACCAUCUAGUAGCUGGUUACCGCCGAAGUUUCCCUCAGGAUAGCAGUGUCGAC
CUUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGGGACUCGGGGGCGAUUUUUAGCCUUCAU
CCAUUCUCAAACUUUAAAUAUGUAAGAAGCCCUUGUUACUUAACUGAACGUGGGCAUUCG
AAUGUAUCGACACUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCG
AACGCGGGGUUAAGGUGCCGGAGUGGACGCUCAUCAGACACCACAAAAGGCGUUAGUACA
UCUUGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGACUGUGUAACAACUC
ACCUGCCGAAUGUACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGUCCCACCCAUACCCCG
CCCUCAGGGUAGAAACGAUGCCCUGAGGAGUAGGCGGCCGUGGAGGUCAGUGACGAAGCC
UAGGGCGUGAGCCCGGGUCGAACGGCCUCUAGUGCAGAUCUUGGUGGUAGUAGCAAAUAC
UUCAAUGAGAACUUGAAGGACCGAAGUGGGGAAAGGUUCCAUGUGAACAGCGGUUGGACA
UGGGUUAGUCGAUCCUAAGCCAUAGGGAAGUUCCGUUUCAAAGGGGCACUCGUGCCCCGU
GUGGCGAAAGGGAAGCCGGUUAAUAUUCCGGCACCUGGAUGUGGGUUUUGCGCGGCAACG
CAACUGAACGCGGAGACGACGGCGGGGGCCCCGGGCAGAGUUCUCUUUUCUUCUUAACGG
UCUAUCACCCUGGAAACAGUUUGUCUGGAGAUAGGGUUUAAUGGCCGGAAGAGCCCGACA
CUUCUGUCGGGUCCGGUGCGCUCUCGACGUCCCUUGAAAAUCCGCGGGAGGGAAUAAUUC
UCACGCCAGGUCGUACUCAUAACCGCAGCAGGUCCCCAAGGUGAACAGCCUCUGGUUGAU
AGAACAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGUAACUUCGGGAAAAGGAUUGG
CUCUAAGGGUUGGGCACGUUGGGCUUUGGGCGGACGCCCUGGGAGCAGAGGGCCUCUAGC
CGGGCAACCGGCCGGCGGCCCUCAGCACCCGGGGUUGAAGCCCUUAGCAGGCUUCGGCCG
UCCGGCGUGCGGUUAACAACCAACUUAGAACUGGUACGGACAGGGGGAAUCUGACUGUCU
AAUUAAAACAUAGCAUUGCGAUGGCCAGAAAGUGGUGUUGACGCAAUGUGAUUUCUGCCC
AGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAAC
UAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGA
UUAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGG
CUUGGCAAAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUG
AAAAGACAUAGGAGGUGUAGAAUAGGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACUC
CUAUUGUUUUUUUACUUAUUCAAUGAAGCGGGGCUGGACUUGCGUCCAACUUCUGGAGUU
AAGGUCCUUCGCGGGCCGACCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGG
CGGCACAUCUGUUAAACCAUAACGCAGGUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAU
CUCCAGUAGAACAAAAGGGUAAAAGUCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAAC
CAUGAAAGUGUGGCCUAUCGAUCCUUUAGUCCCUCGAAAUUUGAGGCUAGAGGUGCCAGA
AAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUU
UGAUCCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUU
GUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUU
ACCCUACUGAUGAACUCGUCGCAAUGGUAAUUCAGCUUAGUACGAGAGGAACCGCUGAUU
CAGAUAAUUGGUUUUUGCGGUUGUCCGACCGGGCAGUGCCGCGAAGCUACCAUCUGCUGG
AUAAUGGCUGAACGCCUCUAAGUCAGAAUCCAUGCCAGAACGCGACGAUACUACCCGCAC
GUUGUAGACGUAUAAGAAUAGGCUCCGGCCUCGUAUCCUAGCAGGCGAUUCCUCCGCCGG
CCUCGAAGUGGCCGUCGGUAAUUCGCGUAUUGCAAUUUAGACACGCGCGGGAUCAAAUCC
UUUGCAGACGACUUAGAUGUGCGAAAGGGUCCUGUAAGCAGUAGAGUAGCCUUGUUGUUA
CGAUCUGCUGAGGGUAAGCCCUCCUUCGCCUAGAUUUCCCAG

Sequence of entity 2 (C2), FASTA

>8PV8_2 5.8S rRNA (chains C2)
AAACUUUCAACAACGGAUCUCUUGGUUCUGGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
AAGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCG
CCGGUAUUCCGGCGGGCAUGCCUGUUCGAGCGUCAU

Sequence of entity 3 (CF), FASTA

>8PV8_3 Large ribosomal subunit protein uL10 (chains CF)
MPKSKRARVYHLTQVNKKGREAKERLFSNIRETIPKYQHCFVFSVDNMRNNYLKDVRHEL
NDCRIFFGKTKLMARALGTTPEEEQADGLHRLTRYLTGTVGLLFTNRDPADIESYFSNLS
QVDFARAGTVAPRTVTVPPGIVYSTGGEVPPEHDVPVSHTLEPELRRLGMPVRMIKGKVC
LGDEKGEASEGYTICKEGEVLDSRQTRLLKLFSICLSEFKVSLLGYWSSASGEVTELEAG
KTRPKREGNRRQAMNGDEMDEDQSSDEDSD

Sequence of entity 4 (CH), FASTA

>8PV8_4 Nucleolar GTP-binding protein 1 (chains CH)
MTGWKDIPPVPTAQEFIDIVLSRTQRRLPTQIRPGFKISRIRAFYTRKVKFTQETCSEKF
GAIISSFPVLSDQHPFHRDLMNILYDADHFKVALGQISTAKNLIETISRDYVRLLKYAQS
LYQCKQLKRAALGRMATLIKRLKDPLIYLDQVRQHLARLPDINPTTRTLLVAGFPNVGKS
SFVRSVTRADTPVEPYAFTTKSLFVGHLDYKYLRYQVIDTPGILDHPLEEMNTIEMQSVT
ALAHLRAAVLYFMDISEQCGFSLKAQINLFKSIKPLFANKMVFIVLNKMDIKKFEELDPE
MQQEINDLTKSGEVEILRASCATQEGVQEVKNHVCERLLVERVSQKLKAGTHSNGNIGTR
LQEVMARIHVATPMDGTTRETFIPEAVKNLKKYDKNDPNRRVLARDIEEANGGAGVFNVD
LRKDWILENPEWKYDKIPEIFDGKNVYDYIDPDIDAKLQALEEEEERLEKEGFYDEDDDL
PDEEEEEILQKAEYIREQHALIRNEAKMRKSLKNRAIIPRKAVKKPLSQLEDHLDQLGVD
TEAIGLRARAQTAQSSRGRSLVRSRGTTADPDAMDIDDGAASAKERLARSRSRARSVAAT
NRLQDGVQGTTLRSKAERQAKLAQRKMNRMARQGEADRHIHASMPKHLFSGKRTIGKTDR
R

Sequence of entity 5 (CK), FASTA

>8PV8_5 Ribosome biogenesis protein NSA2 homolog (chains CK)
MPQNEYIERHRKLHGRRLDAEERARKKAAREGHKNSENAQNLRGLRAKLYAKQRHAQKIQ
MRKAIKQHEERNVKGRPAEKEPSDPIPSYLLDRANPTTAKALSSQIKNKRAEKAARFSVP
IPKVRGISEEEMFKVVKTGKKTHKKGWKRIVTKPTFVGPDFTRRPVKYERFIRPMGLRYK
KANVTHPTLNVTVQLPILSVKKNPSNPLYTQLGVLTKGTIIEVNVSDLGIVTASGKIAWG
RYAQITNNPENDGCVNAVLLV

Sequence of entity 6 (CL), FASTA

>8PV8_6 Putative GTP binding protein (chains CL)
MAGTINKPKKPTSKRKTTRLRAKISKRAAEKKRKERKLARKNPEWRSKLKKDPGIPNLFP
YKERLLQQIEEERIRRKEELLRKKELAKAAKTGADGDNKDDEQMQEDDEHMIREEELDLD
DAMDEDGSDVDESNPLAALVRSARKAAEEYEKELQSGSEMDEDDEDDSDDASDAGSDAGV
ITEVHGGATSRKAYDKVFKQVVEQADVILYVLDARDPEGTRSHDVEQAVMAAAGGGKRLM
LILNKVDLVPPPVLKGWLTYLRRFFPTLPLRASNPAPNARTFSHRDITVQSTSAALFRAL
KAYAAARNLKRAIAVGVIGYPNVGKSSVINALLSRLPGSARGGRTPCPAGAEAGVTTAIR
AVKIDSKLTLLDSPGIVFPSTASSQTFIPKNPVEAHAHLVLLNAIPPKQIEDPVPAVTLL
LKRLSATPELMDRLMQVYDIPPLLKDPSQGGDATMDFLVQVARKRGRLGRGGVPNIQAAA
MTVVTDWRDGRIQGWTEPPKIAVEGVKEGNEGKVVRKIADQEVAPDQKIIVTEWAKEFKL
AGLWGDEEQTEEGDKMEA

Sequence of entity 7 (CN), FASTA

>8PV8_7 Eukaryotic translation initiation factor 6 (chains CN)
MAVRAQFENSNEVGVFATLTNSYCLVALGASENFYSVFEAELQDVIPICRTTIAGTRIIG
RLTAGNRKGLLVPTTTTDQELQHLRNSLPDDIRIQRIEERLSALGNVIVCNDHTALIHPD
LERETEEIIADVLGVEVFRQTIADHVLVGSYMALSNQGGLVHPKTSIQDQDELSSLLGVP
LVAGSVNRGSNVIGGGMVVNDWLAVTGLDTTAPELSVIESVFRLGEGAGPGAINTSMKNT
IVESFY

Sequence of entity 8 (CO), FASTA

>8PV8_8 DUF2423 domain-containing protein (chains CO)
MAKSARASRIKENHQRFKKNIAGPVEAARLERLSAKLMAIAQAPKPDIEMKEESEATAEQ
PKESTQTKDDTAMDVDGAKPTLSGVKSGKSIGRKDSRKRRGKKSSIVFPMKGPKRNNLKK

Sequence of entity 9 (CQ), FASTA

>8PV8_9 Ribosome biogenesis protein RLP24 (chains CQ)
MRIENCFFCGRPAWPSKGITFMRNDGKAFRFCRSKCHKNFKMKRNPRKLKWTKAYRKNAG
KEMVVDSTLQFAARRNVPVRYNRELWQKTLKAMERISEIRARRERVFYKKRMAGKRAREV
AAARKLVAENEHLLPRLRGSEKRRLAELAAERGVDVEELEREELAKLASKKKSKAFGGEV
RRVRVRTDGGVEEITESFGGKNVDEEMDDDDHDDSDRDDDDMDTD

Sequence of entity 10 (Cb), FASTA

>8PV8_10 Zinc finger domain-containing protein (chains Cb)
MGVFAKRTMTKTRRRLRDLDQIERDLRSPRHLQQYKETKAAEDLPGLGLYYCIECAKWFE
SETSLVGHRKGKPHKRRLKQLKEGAYTHEEAMAAIGYRIDNGKKTTEQPKTQDVEMS

Sequence of entity 11 (Cd), FASTA

>8PV8_11 Nucleolar GTP-binding protein 2 (chains Cd)
MGTGKKEKNRLLREGRTPGDPHVKGENFYRSAKKIKTLNILKEGKPIRDSKGKIVKAASF
QSKEVPKAVIEPNRKWFTNTRVISQDTLQSFREAMAEKQKDPYTVLLKSNKLPMSLIRDG
PKLEDGLKKHQAKMTIEREPFSETFGPKAQRKRPKLSFNTVDELAGYSEQSLDSYHARLE
EKKLLSGAAGAAALESEAPVEEDFSVATAKEAIFNKGTSKRIWNELYKVIDSSDVILHVL
DARDPLGTRCRHVEKYLAAEAPHKHLVFVLNKIDLVPSSQAAAWIRILQKDHPTCAMRAS
ITNPFGRGSLIDLLRQFSVLHKDRKQISVGLIGYPNVGKSSIINALRGKAVAKVAPIPGE
TKVWQYVTLMKRIYLIDCPGIVPPNQHDTPEDLLLRGVVRVENVEHPEQYIPAVLRKVKQ
HHMERTYELRGWKDHIEFLEMLARKSGRLLKGGEPDVDGVAKQVLNDFMRGKIPWFTPAP
EPEKGDEPVIEGRAGRLGEMPKKRKREETESVADTSMADSTAAAEPEDESEDEGSDSESE
FSGFSSDSDSEVEVEVGKEAQDDSAPDMIPLDETSDEDEYNEEDDDGEEDGSEDGDEMSD
NDIEDASDIESESESEPSPPKRRKKAR

Sequence of entity 12 (Cz), FASTA

>8PV8_12 rRNA-processing protein (chains Cz)
MNMSETQVNITAAPAPATTKKNLGMRKNGQVWLPAKKAFRPTKGLTSWELRVKKRQEQAA
MKAKEREMKEEKEAERQKRIQAIKERRKKKEEKERYEQLAAKMHKKRLERLKRKEKRNKL
LNS

Ligands and cofactors

ID	Name	Formula	Copies
GTP	Guanosine-5'-triphosphate	C10 H16 N5 O14 P3	2
MG	Magnesium ion	Mg	3
ZN	Zinc ion	Zn	5

Primary citation

Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Thoms, M., Lau, B., Cheng, J. et al. EMBO Rep (2023) 24:e57984-e57984. DOI 10.15252/embr.202357984 · PubMed

Other PDB entries of the same protein (UniProt G0S616 (AlphaFold model), which also has an AlphaFold model), best resolution first:

4NWB 1.8 Å, Crystal structure of Mrt4
8PV7 2.12 Å, Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite…
8PVL 2.19 Å, Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite…
9XB4 2.5 Å, Crystal structure of Mrt4 (L96C) mutant
8PVK 2.55 Å, Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite…
8PV1 2.56 Å, Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite…
8PV2 2.63 Å, Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1
8I9Z 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4
8IA0 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6
8I9X 2.8 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1
8PV3 2.8 Å, Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite…
8PV5 2.86 Å, Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite…

Browse structure collections

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