8T82: PDB entry 8T82
Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes pentafluoropropionic acid. Determined by X-ray diffraction at 1.1 Å resolution. Released 29 Nov 2023.
- Method
- X-ray diffraction
- Resolution
- 1.1 Å
- Organism
- Homo sapiens
- Chains
- 1
- Atoms
- 49
- Mol. weight
- 0.72 kDa
- Ligands
- YWK
- Released
- 29 Nov 2023
Explore 8T82 in 3D
Show helices and sheets
RCSB PDB
PDBe
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| amyloid beta segment 35-MVGGVV-40, racemic mixture | A | protein | 6 | Homo sapiens | P05067 (AlphaFold model) |
Sequence of entity 1 (A), FASTA
>8T82_1 amyloid beta segment 35-MVGGVV-40, racemic mixture (chains A)
MVGGVV
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| YWK | pentafluoropropanoic acid | C3 H F5 O2 | 1 |
Primary citation
Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets. Hazari, A., Sawaya, M.R., Sajimon, M. et al. J Am Chem Soc (2023) 145:25917-25926. DOI 10.1021/jacs.3c11712 · PubMed
Other PDB entries of the same protein (UniProt P05067 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 2FMA 0.85 Å, Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in…
- 6NB9 1.05 Å, Amyloid-Beta (20-34) with L-isoaspartate 23
- 6OIZ 1.1 Å, Amyloid-Beta (20-34) wild type
- 5ONQ 1.17 Å, Alzheimer's Amyloid-Beta Peptide Fragment 29-40 in Complex with Cd-substituted Thermolysin
- 3JQL 1.2 Å, Crystal Structure of the Complex Formed Between Phospholipase A2 and a Hexapeptide…
- 3PZZ 1.29 Å, Structure of an amyloid forming peptide GAIIGL (29-34) from amyloid beta
- 4PQD 1.33 Å, The longer crystal structure of the grow factor like domain from Beta amypoid precusor…
- 5ONP 1.34 Å, Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Cd-substituted Thermolysin
- 5ONR 1.39 Å, Alzheimer's Amyloid-Beta Peptide Fragment 1-40 in Complex with Thermolysin
- 4PWQ 1.4 Å, High-resolution crystal structure of the E1-domain of the amyloid precursor protein
- 7OW1 1.4 Å, Crystal Structure of TAP01 in complex with amyloid beta peptide
- 6O4J 1.4 Å, Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation
Browse structure collections
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