8W17: Lactam bridge synthetic analogue of RgIA

Lactam bridge synthetic analogue of RgIA. Determined by solution NMR. Released 5 Mar 2025.

Method
Solution NMR
Organism
Conus regius
Chains
1
Atoms
123
Mol. weight
1.95 kDa
Released
5 Mar 2025

Explore 8W17 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8W17 contains 1 α-helix and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 0 β-strands

ElementResiduesLengthSheet
α-helix7-115

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Alpha-conotoxin RgIA analogueAprotein15Conus regiusP0C1D0 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>8W17_1 Alpha-conotoxin RgIA analogue (chains A)
EGCCTDPRCRYQCYK

Primary citation

On-resin bicyclization improves synthesis of alpha-conotoxin RgIA4-6. Giribaldi, J., Agwa, A.J., Duorado, M. et al. To be published.

Other PDB entries of the same protein (UniProt P0C1D0 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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