9LKZ: Sodium channel protein PaFPC1

Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana and scorpion alpha toxin LqhaIT. Determined by electron microscopy at 2.87 Å resolution. Released 4 Feb 2026.

Method
Electron microscopy
Resolution
2.87 Å
Organisms
Periplaneta americana, Leiurus hebraeus
Chains
2
Atoms
10,583
Mol. weight
193.2 kDa
Ligands
NAG
Released
4 Feb 2026

Explore 9LKZ in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9LKZ contains 80 α-helices and 24 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 78 helices, 17 β-strands

ElementResiduesLengthSheet
β-strand110-11231
β-strand117-11931
α-helix131-1388
α-helix140-15819
α-helix167-18519
α-helix200-21718
α-helix226-23914
α-helix244-25714
α-helix259-27921
α-helix283-2853
β-strand287-29042
α-helix291-2933
α-helix296-2983
α-helix303-3119
α-helix313-3153
β-strand31612
α-helix325-3273
β-strand33113
β-strand33413
α-helix337-3382
β-strand341-34442
α-helix361-37313
α-helix377-38711
α-helix390-3923
α-helix393-40210
α-helix403-4075
α-helix408-42619
α-helix503-51614
α-helix519-53719
α-helix545-56723
α-helix575-5784
α-helix582-60019
α-helix608-62114
α-helix625-63612
α-helix639-66224
α-helix665-6695
α-helix671-6733
α-helix675-6773
α-helix687-69913
α-helix703-71210
α-helix717-7259
α-helix726-7338
α-helix734-74310
α-helix840-85314
α-helix856-87116
α-helix872-8754
α-helix880-8823
α-helix884-91835
α-helix921-94121
α-helix944-9474
α-helix948-9514
α-helix952-9587
α-helix959-9635
α-helix969-100436
β-strand1010-101234
β-strand101814
α-helix1019-10202
β-strand102615
α-helix1027-10326
β-strand1036-103834
α-helix1047-105812
α-helix1063-10708
β-strand107815
α-helix1079-10802
α-helix1086-10883
α-helix1089-109911
α-helix1106-112217
α-helix1131-114313
α-helix1153-11553
α-helix1158-116710
α-helix1170-118718
α-helix1198-12047
α-helix1206-122318
α-helix1232-124918
α-helix1263-12675
α-helix1268-12714
α-helix1272-12754
α-helix1284-129411
α-helix1296-132126
β-strand132716
β-strand133016
α-helix1339-134911
α-helix1355-13628
α-helix1384-139411
α-helix1395-14028
α-helix1404-142320
α-helix1428-144013
β-strand1447-144937
α-helix1450-14523
α-helix1453-14564
α-helix1457-14593
α-helix1471-14777
β-strand148217
β-strand1486-148837
α-helix1489-150214
Chain C: 2 helices, 7 β-strands
ElementResiduesLengthSheet
β-strand4-528
β-strand619
β-strand7-8210
β-strand12-13210
α-helix14-152
α-helix25-295
β-strand34-3638
β-strand46-4838
β-strand5719

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Sodium channel protein PaFPC1Aprotein1596Periplaneta americanaD0E0C2 (AlphaFold model)
Alpha-insect toxin LqhaITCprotein66Leiurus hebraeusP17728 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>9LKZ_1 Sodium channel protein PaFPC1 (chains A)
MASWSHPQFEKGGGARGGSGGGSWSHPQFEKGFDYKDDDDKGTMADNSPLIREERQRLFR
PYTRAMLTAPSAQPAKENGKTEENKDNSRDKGRGANKDRDGSAHPDQALEQGSRLPARMR
NIFPAELASTPLEDFDPFYKNKKTFVVVTKAGDIFRFSGEKSLWMLDPFTPIRRVAISTM
VQPIFSYFIMITILIHCIFMIMPATQTTYILELVFLSIYTIEVVVKVLARGFILHPFAYL
RDPWNWLDFLVTLIGYITLVVDLGHLYALRAFRVLRSWRTVTIVPGWRTIVDALSLSITS
LKDLVLLLLFSLFVFAVLGLQIYMGVLTQKCVKHFPADGSWGNFTDERWFNYTSNSSHWY
IPDDWIEYPLCGNSSGAGMCPPGYTCLQGYGGNPNYGYTSFDTFGWAFLSVFRLVTLDYW
EDLYQLALRSAGPWHILFFIIVVFYGTFCFLNFILAVVVMSYTHMVKRADEEKAAERELK
KEKKAASVANNTANGQEQTTIEMNGDEAVVIDNNDQAARQQSDPETPAPSVTQRLTDFLC
VWDCCVPWQKLQGAIGAVVLSPFFELFIAVIIVLNITFMALDHHDMNIEFERILRTGNYI
FTSIYIVEAVLKIIALSPKFYFKDSWNVFDFIIVVFAILELGLEGVQGLSVFRSFRLLRV
FRLAKFWPTLNNFMSVMTKSYGAFVNVMYVMFLLLFIFAIIGMQLFGMNYIDNMERFPDG
DLPRWNFTDFLHSFMIVFRALCGEWIESMWDCMLVGDWSCIPFFVAVFFVGNLVILNLLI
ALLLNNYGSFCTSPTSDEEDSKDEDALAQIVRIFKRFKPNLNAVKLSPMKPDSEDIVESQ
EIQGNNIADAEDVLAGEFPPDCCCNAFYKCFPSRPARDSSVQRMWSNIRRVCFLLAKNKY
FQKFVTAVLVITSVLLALEDIYLPQRPVLVNITLYVDYVLTAFFVIEMIIMLFAVGFKKY
FTSKWYWLDFIVVVAYLLNFVLMCAGIEALQTLRLLRVFRLFRPLSKVNGMQVVTSTLVE
AVPHIFNVILVGIFFWLVFAIMGVQLFAGKFYKCVDENSTVLSHEITMDRNDCLHENYTW
ENSPMNFDHVGNAYLSLLQVATFKGWLQIMNDAIDSREVHKQPIRETNIYMYLYFIFFIV
FGSFFILKLFVCILIDIFRQQRRKAEGLSATDSRTQLIYRRAVMRTMSAKPVKRIPKPTC
HPQSLMYDISVNRKFEYTMMILIILNVAVMAIDHYGQSMEFSEVLDYLNLIFIIIFFVEC
VIKVSGLRHHYFKDPWNIIDFLYVVLAIAGLMLSDVIEKYFISPTLLRILRILRVGRLLR
YFQSARGMRLLLLALRKALRTLFNVSFLLFVIMFVYAVFGMEFFMHIRDAGAIDDVYNFK
TFGQSIILLFQLATSAGWDGVYFAIANEEDCRAPDHELGYPGNCGSRALGIAYLVSYLII
TCLVVINMYAAVILDYVLEVYEDSKEGLTDDDYDMFFEVWQQFDPEATQYIRYDQLSELL
EALQPPLQVQKPNKYKILSMNIPICKDDHIFYKDVLEALVKDVFSRRGSPVEAGDVQAPN
VDEAEYKPVSSTLQRQREEYCVRLIQNAWRKHKQQN
Sequence of entity 2 (C), FASTA
>9LKZ_2 Alpha-insect toxin LqhaIT (chains C)
VRDAYIAKNYNCVYECFRDAYCNELCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRVP
GKCHRK

Ligands and cofactors

IDNameFormulaCopies
NAG2-acetamido-2-deoxy-beta-D-glucopyranoseC8 H15 N O64

Primary citation

Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana and scorpion alpha toxin LqhaIT. Jiang, H., Xu, H.Q. To be published.

Other PDB entries of the same protein (UniProt D0E0C2 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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