9LOU: LGP2:dsRNA complex

LGP2:dsRNA complex. Determined by electron microscopy at 3.36 Å resolution. Released 28 Jan 2026.

Method
Electron microscopy
Resolution
3.36 Å
Organisms
Homo sapiens, uncultured archaeon
Chains
3
Atoms
5,280
Mol. weight
85.03 kDa
Ligands
MG, ZN, ADP
Released
28 Jan 2026

Explore 9LOU in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9LOU contains 28 α-helices and 26 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 28 helices, 26 β-strands

ElementResiduesLengthSheet
α-helix5-1511
β-strand20-2341
α-helix31-4414
β-strand50-5451
α-helix57-7014
β-strand77-7931
α-helix90-967
β-strand99-10351
α-helix104-1107
α-helix122-1243
β-strand127-13151
α-helix133-1353
α-helix141-15515
α-helix159-1613
β-strand162-16761
α-helix178-19215
β-strand196-19831
α-helix228-24417
α-helix256-27217
α-helix275-29622
α-helix299-31315
α-helix322-34423
α-helix346-3483
α-helix349-36113
β-strand370-37342
α-helix378-38912
α-helix391-3955
β-strand40012
β-strand40312
β-strand40613
β-strand40914
β-strand41513
α-helix417-42913
β-strand434-43742
β-strand452-45542
α-helix502-51211
α-helix515-54329
α-helix549-5513
β-strand553-55535
β-strand562-56545
α-helix566-5683
β-strand569-57246
β-strand576-57946
α-helix582-5876
β-strand588-59477
α-helix5951
β-strand59714
β-strand604-61297
β-strand618-62587
β-strand629-63357
β-strand639-64245
β-strand645-64735
α-helix652-6543
α-helix664-6718

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
ATP-dependent RNA helicase DHX58Aprotein678Homo sapiensQ96C10 (AlphaFold model)
RNAXRNA12uncultured archaeon
RNAYRNA12uncultured archaeon
Sequence of entity 1 (A), FASTA
>9LOU_1 ATP-dependent RNA helicase DHX58 (chains A)
MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLV
TQHGEEFRRMLDGRWTVTTLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHV
ELTVFSLIVVDECHHTHKDTVYNVIMSQYLELKLQRAQPLPQVLGLTASPGTGGASKLDG
AINHVLQLCANLDTWCIMSPQNCCPQLQEHSQQPCKQYNLSHRRSQDPFGDLLKKLMDQI
HDHLEMPELSRKFGTQMYEQQVVKLSEAAALAGLQEQRVYALHLRRYNDALLIHDTVRAV
DALAALQDFYHREHVTKTQILCAERRLLALFDDRKNELAHLATHGPENPKLEMLEKILQR
QFSSSNSPRGIIFTRTRQSAHSLLLWLQQQQGLQTVDIRAQLLIGAGNSSQSTHMTQRDQ
QEVIRKFQDGTLNLLVATSVAEEGLDIPHCNVVVRYGLLTNEISMVQARGRARADQSVYA
FVATEGSRELKRELINEALETLMEQAVAAVQKMDQAEYQAKIRDLQQAALTKRAAQAAQR
ENQRQQFPVEHVQLLCINCMVAVGHGSDLRKVEGTHHVNVNPNFSNYYNVSRDPVVINKV
FKDWKPGGVISCRNCGEVWGLQMIYKSVKLPVLKVRSMLLETPQGRIQAKKWSRVPFSVP
DFDFLQHCAENLSDLSLD
Sequence of entity 2 (X), FASTA
>9LOU_2 RNA (chains X)
GACUGACUGAGA
Sequence of entity 3 (Y), FASTA
>9LOU_3 RNA (chains Y)
UCUCAGUCAGUC

Ligands and cofactors

IDNameFormulaCopies
MGMagnesium ionMg1
ZNZinc ionZn1
ADPAdenosine-5'-diphosphateC10 H15 N5 O10 P21

Primary citation

LGP2:dsRNA complex. Kurihara, N., Isayama, Y., Nureki, O. et al. To be published.

Other PDB entries of the same protein (UniProt Q96C10 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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