MAP domain-containing protein (SAV0981) is a 144-residue protein from Staphylococcus aureus (strain Mu50 / ATCC 700699). This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: A0A0H3JUK5.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 78.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 57% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 10% |
| Below 50 | Very low: often disordered regions | 22% |
What pLDDT means and how to read it
Serine protease inhibitor that acts as an innate immune evasion factor (PubMed:25161283, PubMed:29114958, PubMed:31622584, PubMed:37269950). Specifically inhibits CTSG and ELANE, the most abundant neutrophil serine proteases (PubMed:25161283, PubMed:29114958, PubMed:31622584, PubMed:37269950). Required both to inhibit the activity of neutrophils and protect S.aureus immune evasion proteins from degradation by neutrophil serine proteases (PubMed:26418545)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8G25 | X-ray | 1.8 Å | C/D/G=31-144 |
| 8G24 | X-ray | 1.82 Å | C=31-144 |
| 8G26 | X-ray | 1.85 Å | C=31-144 |
| 1YN5 | X-ray | 2.2 Å | A/B=42-144 |
| 8GDG | NMR | A=31-144 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.