Agglutinin-like protein 9 (ALS9) is a 1890-residue protein from Candida albicans (strain SC5314 / ATCC MYA-2876). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: A0A1D8PQ86.
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The mean pLDDT of this model is 49.8 (very low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 13% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 25% |
| Below 50 | Very low: often disordered regions | 52% |
What pLDDT means and how to read it
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections (PubMed:17510860, PubMed:22321066, PubMed:22429754). Allele ALS9-2 contributes to endothelial cell adhesion, whereas ALS9-1 does not (PubMed:17600078)
Cell membrane, Secreted, cell wall
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2Y7L | X-ray | 1.49 Å | A=18-328 |
| 2YLH | X-ray | 1.7 Å | A=18-328 |
| 2Y7O | X-ray | 1.75 Å | A=18-328 |
| 2Y7M | X-ray | 1.98 Å | A=18-328 |
| 2Y7N | X-ray | 2.0 Å | A=18-328 |
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