Histone acetyltransferase type B subunit 2 (mis16) is a 430-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O94244.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 90.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 81% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 7% |
What pLDDT means and how to read it
Regulatory subunit of the histone acetylase B (HAT-B) complex (By similarity). The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing (By similarity). Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A (PubMed:15369671, PubMed:24774534, PubMed:24789708, PubMed:25375240). Maintains the deacetylated state of histones specifically in the central core of the centromeres (PubMed:15369671)
Component of the HAT-B complex composed of at least hat1 and hat2. The HAT-B complex binds to histone H4 tail (By similarity). Component of the CENP-A recruiting complex composed of at least mis16, mis19, mis19 and mis20 (PubMed:24774534, PubMed:24789708, PubMed:25375240)
Cytoplasm, Nucleus, Chromosome, centromere, Chromosome, centromere, kinetochore
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6S1R | X-ray | 1.8 Å | A=2-430 |
| 6S1L | X-ray | 1.94 Å | A=2-430 |
| 6S29 | X-ray | 1.99 Å | A/C=2-430 |
| 5WJC | X-ray | 2.3 Å | A=1-430 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.