CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2) is a 341-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O95400.
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The mean pLDDT of this model is 69.0 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 9% |
| 70 to 90 | Confident: backbone generally right | 48% |
| 50 to 70 | Low: treat with caution | 19% |
| Below 50 | Very low: often disordered regions | 25% |
What pLDDT means and how to read it
Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly
Component of the U5 snRNP complex composed of the U5 snRNA and at least PRPF6, PRPF8, SNRNP200, EFTUD2, SNRNP40, DDX23, TXNL4A and CD2BP2. Interacts directly with TXNL4A and PRPF6. Interacts (via GYF domain) with CD2 (via Pro-rich sequence in the cytoplasmic domain). Interacts with PQBP1
Cytoplasm, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1SYX | X-ray | 2.34 Å | B/D/F=262-341 |
| 4BWS | X-ray | 2.5 Å | C/F=280-341 |
| 8Q91 | EM | 3.1 Å | F=1-341 |
| 8Q7Q | EM | 3.2 Å | G=1-341 |
| 8RC0 | EM | 3.2 Å | F=1-341 |
| 8Q7V | EM | 3.8 Å | G=1-341 |
| 8Q7W | EM | 3.9 Å | G=1-341 |
| 8Q7X | EM | 4.6 Å | G=1-341 |
| 1GYF | NMR | A=280-341 | |
| 1L2Z | NMR | A=280-341 |
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