Actin-like protein 6A (ACTL6A) is a 429-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O96019.
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The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 87% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch…
Component of numerous complexes with chromatin remodeling and histone acetyltransferase activity. Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8QR1 | EM | 2.4 Å | K=1-429 |
| 9C57 | EM | 2.75 Å | L/M=1-429 |
| 9WBZ | EM | 2.9 Å | N=1-429 |
| 9CAE | EM | 3.07 Å | M=1-429 |
| 8X15 | EM | 3.2 Å | T=1-429 |
| 8X19 | EM | 3.2 Å | T=1-429 |
| 8X1C | EM | 3.2 Å | T=1-429 |
| 8XVT | EM | 3.2 Å | I/J=1-429 |
| 9C6N | EM | 3.29 Å | L=1-429 |
| 7VDV | EM | 3.4 Å | N=1-429 |
| 9C4B | EM | 3.4 Å | A=1-429 |
| 9WC1 | EM | 3.4 Å | B=1-429 |
| 9CAC | EM | 3.43 Å | M=1-429 |
| 9RL4 | EM | 3.5 Å | J=1-429 |
| 6LTJ | EM | 3.7 Å | J=12-417 |
| 9RN2 | EM | 4.1 Å | J=1-429 |
| 9RMC | EM | 4.2 Å | J=1-429 |
| 7Y8R | EM | 4.4 Å | K=1-429 |
| 9C62 | EM | 5.28 Å | L/M=1-429 |
| 9RN1 | EM | 5.9 Å | J=1-429 |
Showing 20 of 21 experimental structures (best resolution first).
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