Retinol-binding protein 4 (RBP4) is a 201-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P02753.
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The mean pLDDT of this model is 90.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 79% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (PubMed:22665496)
Interacts with TTR (PubMed:10052934, PubMed:19021760, PubMed:5541771, PubMed:7754382). Interaction with TTR prevents its loss by filtration through the kidney glomeruli (Probable). Interacts with STRA6 (PubMed:22665496, PubMed:25910211)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5NU2 | X-ray | 1.5 Å | A=19-200 |
| 5NU7 | X-ray | 1.5 Å | A=19-200 |
| 5NU9 | X-ray | 1.5 Å | A=19-200 |
| 5NU8 | X-ray | 1.59 Å | A=19-200 |
| 5NUA | X-ray | 1.6 Å | A=19-200 |
| 5NUB | X-ray | 1.6 Å | A=19-200 |
| 2WQ9 | X-ray | 1.65 Å | A=19-192 |
| 5NU6 | X-ray | 1.68 Å | A=19-200 |
| 1JYD | X-ray | 1.7 Å | A=19-200 |
| 2WR6 | X-ray | 1.8 Å | A=18-192 |
| 6QBA | X-ray | 1.8 Å | A=19-201 |
| 1JYJ | X-ray | 2.0 Å | A=19-200 |
| 1RBP | X-ray | 2.0 Å | A=19-200 |
| 5NTY | X-ray | 2.0 Å | A=19-200 |
| 4O9S | X-ray | 2.3 Å | A/B=19-201 |
| 4PSQ | X-ray | 2.4 Å | A/B=19-201 |
| 1BRP | X-ray | 2.5 Å | A=19-200 |
| 1BRQ | X-ray | 2.5 Å | A=19-200 |
| 2WQA | X-ray | 2.85 Å | E/F=19-194 |
| 3FMZ | X-ray | 2.9 Å | A/B=19-201 |
Showing 20 of 23 experimental structures (best resolution first).
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