Regulatory protein rop (rop) is a 63-residue protein from Escherichia coli. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P03051.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 93.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 87% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events
Antiparallel homodimer
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1NKD | X-ray | 1.09 Å | A=1-63 |
| 1RPO | X-ray | 1.4 Å | A=1-63 |
| 4DO2 | X-ray | 1.4 Å | A/B=1-63 |
| 2IJK | X-ray | 1.55 Å | A/B=1-63 |
| 7KAE | X-ray | 1.6 Å | A/B=2-57 |
| 1ROP | X-ray | 1.7 Å | A=1-63 |
| 1B6Q | X-ray | 1.8 Å | A=1-63 |
| 2IJH | X-ray | 1.8 Å | A/B/C=1-63 |
| 1GTO | X-ray | 1.82 Å | A/B/C=2-62 |
| 1F4N | X-ray | 1.9 Å | A/B=1-63 |
| 1GMG | X-ray | 1.9 Å | A/B=1-63 |
| 2IJJ | X-ray | 1.9 Å | A/B/C=1-63 |
| 3K79 | X-ray | 1.96 Å | A=2-63 |
| 1QX8 | X-ray | 2.02 Å | A/B=1-63 |
| 1F4M | X-ray | 2.25 Å | A/B/C/D/E/F=1-63 |
| 2IJI | X-ray | 2.3 Å | A=1-63 |
| 2GHY | X-ray | 2.5 Å | A/B=1-63 |
| 1YO7 | X-ray | 2.8 Å | A/B=1-61 |
| 1RPR | NMR | A/B=1-63 |
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