Heat-labile enterotoxin A chain (eltA) is a 258-residue protein from Escherichia coli. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P06717.
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The mean pLDDT of this model is 89.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 75% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 10% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase
Heterohexamer of one A chain and of five B chains
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1LTS | X-ray | 1.95 Å | A=22-206, C=214-254 |
| 1LT3 | X-ray | 2.0 Å | A=19-258 |
| 1LT4 | X-ray | 2.0 Å | A=19-258 |
| 1LTI | X-ray | 2.13 Å | A=19-210, C=211-258 |
| 1LTA | X-ray | 2.2 Å | A=19-206, C=210-258 |
| 1LTT | X-ray | 2.3 Å | A=22-206, C=214-254 |
| 1LTG | X-ray | 2.4 Å | A=19-209, C=210-258 |
| 1HTL | X-ray | 2.5 Å | A=19-209, C=210-258 |
| 1LTB | X-ray | 2.6 Å | A=22-206, C=210-254 |
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