Signal recognition particle 19 kDa protein (SRP19) is a 144-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P09132.
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The mean pLDDT of this model is 85.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 73% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 14% |
What pLDDT means and how to read it
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (By similarity). Mediates binding of SRP54 to the SRP complex (By similarity)
Component of a signal recognition particle complex that consists of a 7SL RNA molecule of 300 nucleotides and 6 protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9 (PubMed:12244299, PubMed:20179341). Interacts with IPO5, IPO7, IPO8, KPNB1 and TNPO1. Interactions with IPO8 and TNPO1 may be involved in SRP19 import into the nucleus (PubMed:11682607)
Cytoplasm, Nucleus, nucleolus, Nucleus, nucleoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1JID | X-ray | 1.8 Å | A=1-120 |
| 7QWQ | EM | 2.83 Å | q=1-144 |
| 1MFQ | X-ray | 3.1 Å | B=14-120 |
| 7NFX | EM | 3.2 Å | q=1-144 |
| 5M73 | X-ray | 3.4 Å | B/F=11-118 |
| 4P3E | X-ray | 3.5 Å | B=1-120 |
| 3KTV | X-ray | 3.8 Å | B/D=1-120 |
| 2J37 | EM | 8.0 Å | B=14-120 |
| 1RY1 | EM | 12.0 Å | B=14-120 |
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