Mitochondrial import receptor subunit TOM40 (TOM40) is a 387-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P23644.
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The mean pLDDT of this model is 77.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 24% |
| 70 to 90 | Confident: backbone generally right | 48% |
| 50 to 70 | Low: treat with caution | 20% |
| Below 50 | Very low: often disordered regions | 8% |
What pLDDT means and how to read it
Channel-forming protein essential for import of protein precursors into mitochondria
Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOM5, TOM6, TOM7, TOM20, TOM22, TOM40 and TOM70). Interacts with mitochondrial targeting sequences. Interacts with FCJ1
Mitochondrion outer membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9J99 | EM | 2.94 Å | A/I=1-387 |
| 7E4H | EM | 3.01 Å | D=1-387 |
| 7E4I | EM | 3.05 Å | D=2-387 |
| 6UCU | EM | 3.06 Å | A/I=1-387 |
| 7VKU | EM | 3.2 Å | X=1-387 |
| 8XKY | EM | 3.42 Å | A/F=1-387 |
| 8W5K | EM | 3.6 Å | F/I=1-387 |
| 8XKW | EM | 3.64 Å | A/F=1-387 |
| 8XKX | EM | 3.7 Å | A/F=1-387 |
| 6JNF | EM | 3.81 Å | A/F=1-387 |
| 6UCV | EM | 4.1 Å | A/I/a/i=1-387 |
| 8HCO | EM | 4.1 Å | A/I=1-387 |
| 8W5J | EM | 4.4 Å | A/I=1-387 |
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