Retinoic acid receptor RXR-beta (RXRB) is a 533-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P28702.
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The mean pLDDT of this model is 70.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 46% |
| 70 to 90 | Confident: backbone generally right | 8% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 36% |
What pLDDT means and how to read it
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE)
Homodimer (in vitro) (PubMed:11782480). Heterodimer with other retinoic acid receptor family members. Binds DNA preferentially as a RAR/RXR heterodimer (PubMed:1310259). Interacts with NR1H3 (PubMed:12970175). Interacts with AKAP13 (By similarity)
Nucleus, Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7A78 | X-ray | 1.72 Å | A=298-533 |
| 5HJP | X-ray | 2.6 Å | A/C=299-533 |
| 5KYA | X-ray | 2.6 Å | B/F=293-528 |
| 5I4V | X-ray | 2.61 Å | B/F=293-528 |
| 1H9U | X-ray | 2.7 Å | A/B/C/D=299-522 |
| 5KYJ | X-ray | 2.8 Å | B/F=293-528 |
| 1UHL | X-ray | 2.9 Å | A=298-533 |
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