Transcription initiation factor IIA subunit 2 (TOA2) is a 122-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P32774.
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The mean pLDDT of this model is 87.5 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 71% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 7% |
What pLDDT means and how to read it
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity
TFIIA is a heterodimer composed of the large TOA1 and a small TOA2 subunits. Interacts with TBP. Interacts with TAF11. Interacts with KAP122
Cytoplasm, Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1NH2 | X-ray | 1.9 Å | D=2-122 |
| 1RM1 | X-ray | 2.5 Å | B=1-122 |
| 1YTF | X-ray | 2.5 Å | D=2-122 |
| 7O4J | EM | 2.9 Å | V=1-122 |
| 7OHA | EM | 2.9 Å | M=1-122 |
| 7OH9 | EM | 3.0 Å | M=1-122 |
| 8CEN | EM | 3.0 Å | V=1-122 |
| 7ML4 | EM | 3.1 Å | V=1-122 |
| 7ZS9 | EM | 3.1 Å | V=1-122 |
| 7O4I | EM | 3.2 Å | V=1-122 |
| 7O75 | EM | 3.2 Å | V=1-122 |
| 7ML2 | EM | 3.4 Å | V=1-122 |
| 7O72 | EM | 3.4 Å | V=1-122 |
| 7O73 | EM | 3.4 Å | V=1-122 |
| 8CEO | EM | 3.6 Å | V=1-122 |
| 8UMI | EM | 3.7 Å | V=1-122 |
| 8UOT | EM | 3.7 Å | V=1-122 |
| 8UOQ | EM | 3.8 Å | V=1-122 |
| 7ML1 | EM | 4.0 Å | V=1-122 |
| 7ZSA | EM | 4.0 Å | V=1-122 |
Showing 20 of 31 experimental structures (best resolution first).
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