Trypsin-3 (PRSS3) is a 304-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P35030.
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The mean pLDDT of this model is 81.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 70% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 26% |
What pLDDT means and how to read it
Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5TP0 | X-ray | 1.25 Å | A=81-304 |
| 3P95 | X-ray | 1.3 Å | A=81-304 |
| 2R9P | X-ray | 1.4 Å | A/B/C/D=81-304 |
| 4DG4 | X-ray | 1.4 Å | A/B/D/G=81-304 |
| 5JBT | X-ray | 1.4 Å | A=81-304 |
| 3P92 | X-ray | 1.6 Å | A=81-304 |
| 9BOT | X-ray | 1.6 Å | A=81-304 |
| 4U32 | X-ray | 1.65 Å | A=81-304 |
| 1H4W | X-ray | 1.7 Å | A=81-304 |
| 9BOS | X-ray | 1.7 Å | A=81-304 |
| 5C67 | X-ray | 1.83 Å | A/B=81-304 |
| 6BX8 | X-ray | 1.98 Å | A/C/E/G=81-304 |
| 6GFI | X-ray | 2.3 Å | A/B=81-304 |
| 3L3T | X-ray | 2.38 Å | A/B/C/D=81-304 |
| 3L33 | X-ray | 2.48 Å | A/B/C/D=81-304 |
| 4U30 | X-ray | 2.5 Å | A/B/C/D=81-304 |
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