Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2) is a 348-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P43627.
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The mean pLDDT of this model is 74.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 49% |
| 70 to 90 | Confident: backbone generally right | 14% |
| 50 to 70 | Low: treat with caution | 10% |
| Below 50 | Very low: often disordered regions | 28% |
What pLDDT means and how to read it
Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9L4I | X-ray | 2.5 Å | D=26-221 |
| 9LRF | X-ray | 2.5 Å | K=22-225 |
| 9LRA | X-ray | 2.6 Å | K=22-225 |
| 2DLI | X-ray | 2.9 Å | A=25-221 |
| 8TMU | X-ray | 2.9 Å | C=22-246 |
| 1EFX | X-ray | 3.0 Å | D/E=22-221 |
| 2DL2 | X-ray | 3.0 Å | A=25-221 |
| 6PA1 | X-ray | 3.01 Å | D/H=22-225 |
| 9L4H | X-ray | 3.1 Å | D=26-221 |
| 9LRH | X-ray | 3.4 Å | K=22-225 |
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