Protein SEC13 homolog (SEC13) is a 322-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P55735.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 89.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 77% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Functions as a component of the nuclear pore complex (NPC) and the COPII coat (PubMed:8972206). At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (PubMed:8972206). Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum (By similarity)
At the nuclear pore: component of the Y-shaped Nup107-160 subcomplex of the nuclear pore complex (NPC) (PubMed:14517296, PubMed:18160040, PubMed:35831510, PubMed:36528027). The Nup107-160 subcomplex includes NUP160, NUP133, NUP107, NUP98, NUP85, NUP43, NUP37, SEH1 and SEC13 (PubMed:18160040). At the COPII coat complex: interacts with SEC31A and SEC31B (PubMed:16495487, PubMed:16957052,…
Cytoplasmic vesicle, COPII-coated vesicle membrane, Endoplasmic reticulum membrane, Nucleus, nuclear pore complex, Lysosome membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3BG1 | X-ray | 3.0 Å | A/D/E/H=1-316 |
| 3BG0 | X-ray | 3.15 Å | A/D/E/H=1-316 |
| 9LWF | EM | 3.41 Å | H/R=1-322 |
| 9OTI | EM | 3.5 Å | H/R=1-322 |
| 9LVK | EM | 3.59 Å | H/R=1-322 |
| 7UHY | EM | 3.66 Å | H=1-322 |
| 9LVJ | EM | 3.82 Å | H/R=1-322 |
| 7R5K | EM | 12.0 Å | N0/N1/N2/N3=1-322 |
| 5A9Q | EM | 23.0 Å | 6/F/O/X=1-322 |
| 7PEQ | EM | 35.0 Å | AF/BF/CF/DF=1-322 |
| 7R5J | EM | 50.0 Å | N0/N1/N2/N3=1-322 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.