Protein max (MAX) is a 160-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P61244.
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The mean pLDDT of this model is 81.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 53% |
| 70 to 90 | Confident: backbone generally right | 9% |
| 50 to 70 | Low: treat with caution | 36% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MYC or MAD. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the…
Nucleus, Cell projection, dendrite
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6G6K | X-ray | 1.35 Å | B/D=22-103 |
| 1NKP | X-ray | 1.8 Å | B/E=23-102 |
| 1NLW | X-ray | 2.0 Å | B/E=24-99 |
| 6G6L | X-ray | 2.2 Å | B/D/F/H=22-103 |
| 6G6J | X-ray | 2.25 Å | B/D=22-103 |
| 5EYO | X-ray | 2.39 Å | A/C=22-107 |
| 7RCU | X-ray | 2.69 Å | A/B/E/F/I/J/M/N=24-51, Q/R/S/T/U/V/W/X=59-78 |
| 1HLO | X-ray | 2.8 Å | A/B=4-92 |
| 1AN2 | X-ray | 2.9 Å | A=22-107 |
| 8OTS | EM | 3.3 Å | N=22-102 |
| 8OTT | EM | 3.3 Å | N=23-73 |
| 1R05 | NMR | A/B=22-103 |
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