P83876: Thioredoxin-like protein 4A (TXNL4A)

Thioredoxin-like protein 4A (TXNL4A) is a 142-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P83876.

Gene
TXNL4A
Organism
Homo sapiens
Length
142 residues
Mean pLDDT
88.6
Model
AF-P83876-F1 v6
Model created
1 Aug 2025
PDB structures
32

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Model confidence (pLDDT)

The mean pLDDT of this model is 88.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate72%
70 to 90Confident: backbone generally right22%
50 to 70Low: treat with caution3%
Below 50Very low: often disordered regions4%

What pLDDT means and how to read it

Function

Plays a role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex)

Subunit structure

Component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). Component of the U5 snRNP complex (PubMed:10610776). Component of the U4/U6-U5 tri-snRNP complex (PubMed:26912367). The U4/U6-U5 tri-snRNP complex is a building block of the precatalytic spliceosome (spliceosome B complex) (PubMed:26912367, PubMed:28781166). The U4/U6-U5 tri-snRNP complex is composed of the U4,…

Subcellular location

Nucleus

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
1QGVX-ray1.4 ÅA=1-142
4BWQX-ray2.1 ÅA/C/E/G=4-137
1SYXX-ray2.35 ÅA/C/E=1-142
4BWSX-ray2.5 ÅA/D=4-137
4CDOX-ray2.5 ÅA/C=4-138
8H6LEM2.6 Å4F=1-142
8H6KEM2.7 Å4F=1-142
6QW6EM2.92 Å5D=1-142
8Q7NEM3.1 ÅD=1-142
8QOZEM3.1 ÅD=1-142
8QPEEM3.1 ÅD=1-142
8H6EEM3.2 Å4F=1-142
8H6JEM3.25 Å4F=1-142
6QX9EM3.28 Å5D=1-142
8QP8EM3.5 ÅD=1-142
8QPAEM3.7 ÅD=1-142
8QPBEM3.7 ÅD=1-142
6AHDEM3.8 ÅO=1-142
8QP9EM4.1 ÅD=1-142
8QZSEM4.1 ÅD=1-142

Showing 20 of 32 experimental structures (best resolution first).

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About this viewer

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