GTP-binding protein GTR1 (GTR1) is a 310-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q00582.
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The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 82% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 2% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions (PubMed:26510498, PubMed:28993463, PubMed:32801125). Also required for TORC1 inactivation during nitrogen starvation (PubMed:28993463). Required for intracellular sorting of GAP1 out of the endosome (PubMed:16732272). Functionally associated with the inorganic phosphate transporter PHO84, and may be involved in regulating its function or localization (PubMed:1620108)
Heterodimer; with GTR2 (PubMed:21816923). Component of the GSE complex composed of GTR1, GTR2, SLM4, MEH1 and LTV1 (PubMed:16732272). Interacts with GTR2; the interaction is direct (PubMed:21816923). Interacts with TOR1 (PubMed:29698392)
Vacuole membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 3R7W | X-ray | 2.77 Å | A/C=8-310 |
| 4ARZ | X-ray | 3.1 Å | A=1-310 |
| 9H4Q | EM | 3.1 Å | a=1-310 |
| 6JWP | X-ray | 3.2 Å | A/F=1-310 |
| 9H5K | EM | 3.2 Å | a/b=1-310 |
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