Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is a 184-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q02223.
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The mean pLDDT of this model is 64.9 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 17% |
| 70 to 90 | Confident: backbone generally right | 23% |
| 50 to 70 | Low: treat with caution | 27% |
| Below 50 | Very low: often disordered regions | 33% |
What pLDDT means and how to read it
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK
Associates with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6
Cell membrane, Endomembrane system
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4ZFO | X-ray | 1.9 Å | F/K=1-54 |
| 1XU2 | X-ray | 2.35 Å | R/S/T=5-51 |
| 8HXQ | X-ray | 2.4 Å | C/D=1-54 |
| 1OQD | X-ray | 2.6 Å | K/L/M/N/O/P/Q/R=8-46 |
| 6J7W | X-ray | 2.6 Å | C/D=6-44 |
| 8HXR | X-ray | 2.7 Å | C/D=1-54 |
| 8QYA | X-ray | 2.72 Å | A=6-41 |
| 8QYB | X-ray | 3.09 Å | A=7-41 |
| 8QY9 | X-ray | 3.1 Å | A=7-41 |
| 9MQO | X-ray | 3.18 Å | A/D/G/J/M/P=1-54 |
| 2KN1 | NMR | A=2-50 |
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