Unconventional myosin-Va (MYO5A) is a 1829-residue protein from Gallus gallus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q02440.
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The mean pLDDT of this model is 77.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 28% |
| 70 to 90 | Confident: backbone generally right | 48% |
| 50 to 70 | Low: treat with caution | 14% |
| Below 50 | Very low: often disordered regions | 11% |
What pLDDT means and how to read it
Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation
May be a homodimer, which associates with multiple calmodulin or myosin light chains
Golgi apparatus membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1W7J | X-ray | 2.0 Å | A=1-792 |
| 1OE9 | X-ray | 2.05 Å | A=1-792 |
| 1W8J | X-ray | 2.7 Å | A/B/C/D=1-766 |
| 7PMD | EM | 2.9 Å | A=1-792 |
| 7PME | EM | 2.9 Å | A/D=1-792 |
| 1W7I | X-ray | 3.0 Å | A=1-792 |
| 7PM6 | EM | 3.0 Å | A/D=1-792 |
| 7PM5 | EM | 3.1 Å | A=1-792 |
| 7PLU | EM | 3.2 Å | A/D=1-792 |
| 7PLY | EM | 3.2 Å | A=1-792 |
| 7PLZ | EM | 3.2 Å | A/D=1-792 |
| 7PLT | EM | 3.3 Å | A=1-792 |
| 7PMG | EM | 3.3 Å | A=1-792 |
| 7PMI | EM | 3.3 Å | A=1-792 |
| 7PML | EM | 3.3 Å | A=1-792 |
| 7PMF | EM | 3.4 Å | A=1-792 |
| 7PMH | EM | 3.4 Å | A=1-792 |
| 7PMJ | EM | 3.4 Å | A=1-792 |
| 7PLV | EM | 3.5 Å | A=1-792 |
| 7PLW | EM | 3.5 Å | A=1-792 |
Showing 20 of 31 experimental structures (best resolution first).
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