Colicin-E7 immunity protein (imm) is a 87-residue protein from Escherichia coli. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q03708.
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The mean pLDDT of this model is 96.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 98% |
| 70 to 90 | Confident: backbone generally right | 2% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5WNW | X-ray | 1.79 Å | C=6-45 |
| 1CEI | X-ray | 1.8 Å | A=1-87 |
| 1UNK | X-ray | 1.8 Å | A/B/C/D=1-87 |
| 2JB0 | X-ray | 1.91 Å | A=1-87 |
| 1AYI | X-ray | 2.0 Å | A=1-87 |
| 1MZ8 | X-ray | 2.0 Å | A/C=1-87 |
| 1ZNV | X-ray | 2.0 Å | A/C=1-87 |
| 2ERH | X-ray | 2.0 Å | A=1-87 |
| 2JAZ | X-ray | 2.03 Å | A/C=1-87 |
| 1UJZ | X-ray | 2.1 Å | A=1-87 |
| 2JBG | X-ray | 2.2 Å | A/C=1-87 |
| 7CEI | X-ray | 2.3 Å | A=1-87 |
| 4F37 | X-ray | 2.57 Å | A/B=2-87 |
| 2K0D | NMR | X=2-87 |
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