Q08723: 26S proteasome regulatory subunit RPN8 (RPN8)

26S proteasome regulatory subunit RPN8 (RPN8) is a 338-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q08723.

Gene: RPN8
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length: 338 residues
Mean pLDDT: 84.0
Model: AF-Q08723-F1 v6
Model created: 1 Aug 2025
PDB structures: 38

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Model confidence (pLDDT)

The mean pLDDT of this model is 84.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT band	Meaning	Share of residues
Above 90	Very high: backbone and side chains are usually accurate	46%
70 to 90	Confident: backbone generally right	41%
50 to 70	Low: treat with caution	6%
Below 50	Very low: often disordered regions	7%

What pLDDT means and how to read it

Function

Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB ID	Method	Resolution	Chains and residues
5W83	X-ray	1.55 Å	A=1-338
4O8Y	X-ray	1.95 Å	A=2-178
4O8X	X-ray	1.99 Å	A=2-178
4OCM	X-ray	1.99 Å	A/D=1-185
4OCN	X-ray	2.25 Å	A/D=1-185
4OWP	X-ray	2.35 Å	A=1-186
4OCL	X-ray	2.4 Å	A/D=1-185
5U4P	X-ray	2.5 Å	A=1-177
3JCK	EM	3.5 Å	E=1-338
9CGC	EM	3.61 Å	U=1-338
6J2Q	EM	3.8 Å	U=1-338
6J2X	EM	3.8 Å	U=1-338
5MPD	EM	4.1 Å	U=1-338
6FVT	EM	4.1 Å	U=1-304
5WVK	EM	4.2 Å	U=1-338
5MPE	EM	4.5 Å	U=1-338
6FVU	EM	4.5 Å	U=1-304
6FVW	EM	4.5 Å	U=1-304
6J30	EM	4.5 Å	U=1-338
3JCP	EM	4.6 Å	U=1-338

Showing 20 of 38 experimental structures (best resolution first).

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