Small glutamine-rich tetratricopeptide repeat-containing protein 2 (SGT2) is a 346-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q12118.
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The mean pLDDT of this model is 77.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 49% |
| 70 to 90 | Confident: backbone generally right | 20% |
| 50 to 70 | Low: treat with caution | 13% |
| Below 50 | Very low: often disordered regions | 19% |
What pLDDT means and how to read it
Co-chaperone that binds to the molecular chaperone Hsp70 (SSA1 and SSA2). Regulates Hsp70 ATPase activity (By similarity). Required for recovery from heat shock
Interacts with HSC82, HSP104, MDY2, SSA1 and SSA2
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5LYP | X-ray | 1.55 Å | A=93-229 |
| 3ZDM | X-ray | 1.8 Å | A/B/D/E=1-72 |
| 5LYN | X-ray | 2.0 Å | A/B=96-225 |
| 2LXB | NMR | A/B=2-72 | |
| 2LXC | NMR | B/C=2-72 | |
| 4ASV | NMR | A/B=1-78 | |
| 4ASW | NMR | A/B=1-78 | |
| 9LLV | NMR | A/B=1-346 |
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