IGK@ protein (IGK@) is a 236-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Jun 2022. UniProt accession: Q6P5S8.
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The mean pLDDT of this model is 91.8 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 87% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6UGS | X-ray | 1.95 Å | B/L=21-236 |
| 2NY1 | X-ray | 1.99 Å | C=21-234 |
| 2NXY | X-ray | 2.0 Å | C=21-234 |
| 2NY2 | X-ray | 2.0 Å | C=21-234 |
| 2NY3 | X-ray | 2.0 Å | C=21-234 |
| 2NY4 | X-ray | 2.0 Å | C=21-234 |
| 2NXZ | X-ray | 2.04 Å | C=21-234 |
| 6UGT | X-ray | 2.15 Å | B/L=21-236 |
| 2NY0 | X-ray | 2.2 Å | C=21-234 |
| 6UGU | X-ray | 2.2 Å | B/L=21-236 |
| 6UGV | X-ray | 2.4 Å | B/L=21-236 |
| 6AL4 | X-ray | 2.45 Å | A/C/E=21-49, A/C/E=52-236 |
| 2NY5 | X-ray | 2.5 Å | L=21-234 |
| 2NY6 | X-ray | 2.8 Å | C=21-234 |
| 6V8Z | EM | 2.9 Å | F/L/R=21-235 |
| 6AL5 | X-ray | 3.0 Å | L=21-49, L=52-236 |
| 5WKO | X-ray | 3.49 Å | B/D/F/H/J/L=97-107, B/D/F/H/J/L=131-234 |
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