Q7Z3B4: Nucleoporin p54 (NUP54)

Nucleoporin p54 (NUP54) is a 507-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q7Z3B4.

Gene
NUP54
Organism
Homo sapiens
Length
507 residues
Mean pLDDT
76.4
Model
AF-Q7Z3B4-F1 v6
Model created
1 Aug 2025
PDB structures
10

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 76.4 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate44%
70 to 90Confident: backbone generally right29%
50 to 70Low: treat with caution5%
Below 50Very low: often disordered regions22%

What pLDDT means and how to read it

Function

Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane

Subunit structure

Component of the p62 complex, a complex composed of NUP62, NUP54, and the isoform p58 and isoform p45 of NUP58. Interacts with NUTF2

Subcellular location

Nucleus, nuclear pore complex, Nucleus membrane

Disease associations

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
7N8RX-ray1.2 ÅA/B=63-68
4JNUX-ray1.44 ÅA/B/C/D=453-491
4JO7X-ray1.75 ÅB/D/F/H=453-491
4JNVX-ray1.85 ÅA/B/C/D=453-491
4JO9X-ray2.5 ÅA/C=453-491
7R5KEM12.0 ÅH0/H1/H2/H3=1-507
5IJNEM21.4 ÅF/L/R/X=1-507
5IJOEM21.4 ÅF/L/R/X=1-507
7PEREM35.0 ÅF/L/R/X=1-507
7R5JEM50.0 ÅH0/H1/H2/H3=1-507

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.