Far upstream element-binding protein 1 (FUBP1) is a 644-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96AE4.
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The mean pLDDT of this model is 63.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 16% |
| 70 to 90 | Confident: backbone generally right | 28% |
| 50 to 70 | Low: treat with caution | 16% |
| Below 50 | Very low: often disordered regions | 41% |
What pLDDT means and how to read it
Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription
Found in a complex with PUF60 and far upstream element (FUSE) DNA segment. Interacts with PUF60 and JTV1
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4LIJ | X-ray | 1.8 Å | A/B/C=86-175 |
| 6Y24 | X-ray | 1.86 Å | A=365-455 |
| 6Y2D | X-ray | 1.9 Å | A/B/C/D=185-259 |
| 6Y2C | X-ray | 2.0 Å | A/B=261-351 |
| 1J4W | NMR | A=278-447 | |
| 2KXH | NMR | B=27-52 | |
| 8P25 | NMR | A=21-56 |
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