Nucleoporin SEH1 (SEH1L) is a 360-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q96EE3.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 86.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 73% |
| 70 to 90 | Confident: backbone generally right | 12% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 9% |
What pLDDT means and how to read it
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC (PubMed:15146057, PubMed:17363900). The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore (PubMed:15146057, PubMed:17363900)
Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC) (PubMed:17360435). The Nup107-160 subcomplex includes NUP160, NUP133, NUP107, NUP98, NUP85, NUP43, NUP37, SEH1 and SEC13 (PubMed:17360435). The SEH1 subunit appears to be only weakly associated with the Nup107-160 subcomplex (PubMed:17360435). Component of the GATOR2 subcomplex, composed of MIOS, SEC13, SEH1L, WDR24 and…
Chromosome, centromere, kinetochore, Nucleus, nuclear pore complex, Lysosome membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9LWF | EM | 3.41 Å | E/F/G/O/P/Q=1-357 |
| 9OTI | EM | 3.5 Å | E/F/G/O/P/Q=1-360 |
| 9LVK | EM | 3.59 Å | E/F/G/O/P/Q=1-357 |
| 7UHY | EM | 3.66 Å | E/F/G=1-357 |
| 9LVJ | EM | 3.82 Å | E/F/G/O/P/Q=1-357 |
| 7R5K | EM | 12.0 Å | O0/O1/O2/O3=1-360 |
| 5A9Q | EM | 23.0 Å | 7/G/P/Y=1-360 |
| 7PEQ | EM | 35.0 Å | AG/BG/CG/DG=1-360 |
| 7R5J | EM | 50.0 Å | O0/O1/O2/O3=1-360 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.