Forkhead box protein C2 (FOXC2) is a 501-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q99958.
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The mean pLDDT of this model is 55.2 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 15% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 22% |
| Below 50 | Very low: often disordered regions | 59% |
What pLDDT means and how to read it
Transcriptional activator
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6AKP | X-ray | 2.32 Å | C=72-172 |
| 6AKO | X-ray | 2.4 Å | C=72-172 |
| 6LBM | X-ray | 2.84 Å | C=72-172 |
| 6O3T | X-ray | 3.06 Å | A/B=70-164 |
| 1D5V | NMR | A=69-162 |
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